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Chemical Structure| 73544-82-8 Chemical Structure| 73544-82-8

Structure of 73544-82-8

Chemical Structure| 73544-82-8

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Product Details of [ 73544-82-8 ]

CAS No. :73544-82-8
Formula : C13H10ClNO2
M.W : 247.68
SMILES Code : OC1=CC=CC(C(NC2=CC=C(C=C2)Cl)=O)=C1
MDL No. :MFCD00744403

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Application In Synthesis of [ 73544-82-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 73544-82-8 ]

[ 73544-82-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 73544-82-8 ]
  • [ 13790-39-1 ]
  • N-(4-chlorophenyl)-3-((6,7-dimethoxyquinazolin-4-yl)oxy)benzamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
89% With potassium carbonate; In N,N-dimethyl-formamide; at 80℃; for 24h; General procedure: 138.6 mg (1 mmol) hydroxybenzoic acid in 5 mL THF was added three drops of DMF and reactedwith oxalyl chloride 0.5 mL in 0 C. After 1.5 h reaction, the reaction liquid was dissolved in THFand HCl, which was dissolved in THF solution of aniline derivatives. After 3 h, the reaction mixturewas evaporated; the crude product was purified by column chromatography to obtain compounds 10.Compounds 10 were further reacted with compounds 5, 6, 7 in the presence of K2CO3 to obtain thefinal products 11a-i.
 

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