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Chemical Structure| 73663-61-3 Chemical Structure| 73663-61-3

Structure of 73663-61-3

Chemical Structure| 73663-61-3

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Product Details of [ 73663-61-3 ]

CAS No. :73663-61-3
Formula : C11H11NO3
M.W : 205.21
SMILES Code : COC1=CC=C(C2=CN=CO2)C=C1OC

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Application In Synthesis of [ 73663-61-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 73663-61-3 ]

[ 73663-61-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5460-32-2 ]
  • [ 73663-61-3 ]
  • [ 1394840-87-9 ]
YieldReaction ConditionsOperation in experiment
51% With copper(l) iodide; sodium carbonate; triphenylphosphine; In N,N-dimethyl-formamide; at 160℃; for 3h; A suspension of 0.212 g of Na2C03 (2 mmol), 0.262 g of PPh3 (1 mmol), 0.206 g (1 mmol) of 31 and 0.316 g of 4-iodoveratrole (1.2 mmol) was formed in 1 mL of DMF. Then, 0.190 g (1 mmol) of Cul was added. The mixture was stirred at 160 C for 3 h and quenched by pouring into 50 mL of water containing 5% NH4+OH~. The product was extracted with 50 mL DCM, the organic layer dried and concentrated, and the crude product purified by PTLC to give 0.174 g (51% yield) of 32 as a yellow solid. 1H NMR (200 MHz, CDC13) δ 7.60 (d, / = 8.4 Hz, 1H), 7.54, (bs, 1H), 7.24 (s, 1H), 7.19 (bs, 1H), 7.10 (s, 1H), 6.90-6.83 (m, 2H), 3.91-3.86 (4 overlapping multiplets, 12H). 13C NMR (50 MHz, CDC13) δ 160.7, 150.9, 149.3, 149.2, 132.1, 132.0, 122.0, 121.2, 120.4, 119.3, 117.1, 111.5, 111.1, 109.1, 107.5, 56.01, 55.92
 

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