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Chemical Structure| 7383-63-3 Chemical Structure| 7383-63-3

Structure of 7383-63-3

Chemical Structure| 7383-63-3

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Product Details of [ 7383-63-3 ]

CAS No. :7383-63-3
Formula : C9H10O2S
M.W : 182.24
SMILES Code : SCC(OCC1=CC=CC=C1)=O
MDL No. :MFCD04070643
InChI Key :XTCXSNIRIUQZLY-UHFFFAOYSA-N
Pubchem ID :431757

Safety of [ 7383-63-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301+H311+H331-H315-H319
Precautionary Statements:P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P405
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 7383-63-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7383-63-3 ]

[ 7383-63-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7383-63-3 ]
  • [ 146137-78-2 ]
  • benzyl 5-trifluoromethylbenzo[b]thiophene-2-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
6.54 g With potassium carbonate; In N,N-dimethyl-formamide; at 60℃; for 2h; A mixture of 5.02 g of 2-fluoro-5-(trifluoromethyl) benzaldehyde, 5.00 g of benzyl mercaptoacetate, 4.69 g of potassium carbonate, and 20 ml of N,N-dimethylformamide was stirred for 2 hours at 60 C. The reaction mixture was cooled to room temperature, water was added thereto, and extraction was performed three times by using tert-butyl methyl ether. The collected organic layer was washed with water and saturated saline, dried over magnesium sulfate, and then concentrated under reduced pressure. The residues were subjected to silica gel colunm chromatography, thereby obtaining 6.54 g of benzyl 5-trifluoromethylbenzo[b] thiophene-2-carboxylate (hereinafier, described as a “compound 150 of the present invention”). Compound 150 of the Present Invention 12403] ‘H-NMR (CDC13) ö: 8.16-8.15 (m, 2H), 7.99-7.96(m, 1H), 7.68-7.66 (m, 1H), 7.48-7.46 (m, 2H), 7.44-7.35 (m,3H), 5.41 (s, 2H).
 

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