Alternatived Products of [ 74592-71-5 ]
Product Details of [ 74592-71-5 ]
CAS No. : | 74592-71-5 |
MDL No. : | MFCD02666050 |
Formula : |
C11H14O3
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
194.23
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 74592-71-5 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 74592-71-5 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 74592-71-5 ]
- 1
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[ 74592-71-5 ]
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[ 33509-43-2 ]
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[ 1621091-13-1 ]
Yield | Reaction Conditions | Operation in experiment |
72% |
With trichlorophosphate at 90℃; for 8h; |
1.1 5.2 General procedure for the syntheses of 3-tert-butyl-7-(aryloxymethyl)-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-ones (5a-5n)
General procedure: An equimolar mixtures of 4-amino-6-tert-butyl-3-mercapto-1,2,4-triazine-5(H)-one (0.01mol) (3) and substituted aryloxyacetic acids (0.01mol) (4) were condensed in presence of POCl3 at 90°C, for 8h. The reactions were carried out in dry condition. The reaction mixtures were cooled and poured into crushed ice drop wise with vigorous shaking, yielded solid product, filtered and recrystallized from ethanol to afford analytical samples (5a-5n) (Scheme 2). |
Reference:
[1]Castelino, Prakash Anil; Naik, Prashantha; Dasappa, Jagadeesh Prasad; Sujayraj; Sharath Chandra; Chaluvaiah, Kumara; Nair, Ramya; Sandya Kumari; Kalthur, Guruprasad; Adiga, Satish Kumar
[European Journal of Medicinal Chemistry, 2014, vol. 84, p. 194 - 199]