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Chemical Structure| 7511-68-4 Chemical Structure| 7511-68-4

Structure of 7511-68-4

Chemical Structure| 7511-68-4

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Product Details of [ 7511-68-4 ]

CAS No. :7511-68-4
Formula : C22H22O3
M.W : 334.41
SMILES Code : COC1=CC=C(C(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)C=C1

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Application In Synthesis of [ 7511-68-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7511-68-4 ]

[ 7511-68-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 3010-81-9 ]
  • [ 7511-68-4 ]
YieldReaction ConditionsOperation in experiment
94% General procedure: Sodium borohydride (8.0 mg, 95%, 0.20 mmol) was added to a solution of aryl alcohol (1a-i, 0.20 mmol) in MeCN (2.0 mL) under an argon atmosphere at 0 C. The mixture was stirred at 0 C for 15 min. Trimethylsilyl chloride (52 μL, 98%, 0.40 mmol) and potassium iodide (33.2 mg, 99%, 0.20 mmol) were added to the mixture at 0 C. The reaction mixture was stirred at room temperature (rt) under an argon atmosphere until no further TLC changes were observed. After the mixture was diluted with EtOAc (5 mL), the reaction was quenched by the addition of a saturated aqueous NaHCO3 solution (2 mL) and Na2S2O3 solution (2 mL). The layers were separated. The aqueous layer was extracted with EtOAc (5 mL). The combined organic layer was washed with water, brine, dried over anhydrous Na2SO4, and concentrated. The residue was purified by silica gel chromatography to give the corresponding product.
 

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