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Chemical Structure| 7512-20-1 Chemical Structure| 7512-20-1

Structure of 7512-20-1

Chemical Structure| 7512-20-1

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Product Details of [ 7512-20-1 ]

CAS No. :7512-20-1
Formula : C16H14O
M.W : 222.28
SMILES Code : CC(O)C1=C2C=CC=CC2=CC3=CC=CC=C13
MDL No. :MFCD00039422

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Application In Synthesis of [ 7512-20-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 7512-20-1 ]

[ 7512-20-1 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 784-04-3 ]
  • [ 7512-20-1 ]
  • [ 7512-20-1 ]
YieldReaction ConditionsOperation in experiment
2 g With Trimethyl borate; dimethylsulfide borane complex; (1R,2S)-1-Amino-2-indanol; In tetrahydrofuran; at 0℃; for 12h; At first, B(OMe)3 (3.1 cm3, 2.9 g, 28 mmol) was added to a solution of (1R,2S)-1-aminoindan-2-ol (0.4 g, 3 mmol, freshly crystallised with toluene) in dry THF (2 cm3) and stirred at rt for 0.5 h. Next, BH3.DMS complex (2.7 cm3, 2.2 g, 28 mmol) in dry THF (2 cm3) was added and the resulting solution cooled to 0 C before the addition of <strong>[784-04-3]1-anthracen-9-yl ethanone</strong> 4 (5.0 g, 23 mmol) in dry THF (5 cm3). The reaction mixture was stirred for 12 h at 0 C, quenched by the slow addition of MeOH (20 cm3) and allowed to warm to rt. Water was added (20 cm3) and the product extracted with CH2Cl2 (3 × 20 cm3), washed with 1 M HCl (10 cm3) and water (10 cm3) and the organic extracts dried over MgSO4. Filtration and removal of the solvent gave the title compound (S)-1 (5.1 g, 100%, 75% ee) as an orange solid. Repeated recrystallisation from CH2Cl2/petroleum ether 40-60 afforded a yellow-orange powder (2.0 g, >99.8% ee); inlMMLBox (c 1, CHCl3) [lit.4 -18.8, (c 1.1, CHCl3) ee >99% (S)-enantiomer].
  • 4
  • [ 74928-67-9 ]
  • [ 784-04-3 ]
  • [ 7512-20-1 ]
  • 5
  • [ 784-04-3 ]
  • (S)-1-(1,2,3,4-tetrahydroanthracene-9-yl)ethanol [ No CAS ]
  • (S)-1-(9,10-dihydroanthracene-9-yl)ethanol [ No CAS ]
  • (R)-1-(1,2,3,4-tetrahydroanthracene-9-yl)ethanol [ No CAS ]
  • (R)-1-(9,10-dihydroanthracene-9-yl)ethanol [ No CAS ]
  • [ 7512-20-1 ]
  • [ 7512-20-1 ]
 

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