Name: Regorafenib | BAY 73-4506; Fluoro-Sorafenib
Brand: Ambeed
SKU: A177150
Rating: 4.6 (156 reviews)

NCT02288078	Rectal Cancer	Phase 2	Unknown	September 2016	Japan ... More >> Saiseikai Fukuoka General Hospital Recruiting Fukuoka, Japan, 810-0001 Contact: Yasunori Emi, MD, PhD +81-92-771-8151 emi-y@saiseikai-hp.chuo.fukuoka.jp Less <<
NCT03347292	Carcinoma, Hepatocellular	Phase 1	Recruiting	February 17, 2021	United States, California ... More >> USC Norris Hospital and Clinics Recruiting Los Angeles, California, United States, 90033 United States, Florida H. Lee Moffitt Cancer Center & Research Institute Recruiting Tampa, Florida, United States, 33612 United States, New York Mount Sinai Medical Center Recruiting New York, New York, United States, 10029 United States, Washington Seattle Cancer Care Alliance Recruiting Seattle, Washington, United States, 98109-1023 Germany Universitätsklinikum Köln Not yet recruiting Köln, Nordrhein-Westfalen, Germany, 50937 Universitätsmedizin der Johannes Gutenberg Universität Mainz Not yet recruiting Mainz, Rheinland-Pfalz, Germany, 55131 Less <<
NCT01187615	Small Cell Lung Carcinoma	Phase 1	Terminated	-	United States, Connecticut ... More >> New Haven, Connecticut, United States, 06519 United States, Nevada Las Vegas, Nevada, United States, 89135-3011 United States, New York New York, New York, United States, 10065 United States, North Carolina Chapel Hill, North Carolina, United States, 27599 Less <<
NCT02106858	-		Recruiting	May 7, 2019	Korea, Republic of ... More >> Recruiting Multiple Locations, Korea, Republic of Less <<
NCT02042144	-		Completed	-	Argentina ... More >> Multiple Locations, Argentina Austria Multiple Locations, Austria Czechia Multiple Locations, Czechia Denmark Multiple Locations, Denmark France Multiple Locations, France Italy Multiple Locations, Italy Luxembourg Multiple Locations, Luxembourg Mexico Multiple Locations, Mexico Netherlands Multiple Locations, Netherlands Singapore Multiple Locations, Singapore Spain Multiple Locations, Spain Switzerland Multiple Locations, Switzerland Taiwan Multiple Locations, Taiwan Less <<
NCT03386825	-		Completed	-	Belgium ... More >> Belgium Multiple Locations, Belgium Less <<
NCT01318265	Pharmacokinetics	Phase 1	Completed	-	United States, Massachusetts ... More >> Brighton, Massachusetts, United States, 02135 Less <<
NCT02788006	Colorectal Adenocarcinoma	Phase 2	Unknown	May 2018	France ... More >> CHU SUD - Service Oncologie Médicale Recruiting Amiens, France Contact: Bruno CHAUFFERT chauffert.bruno@chu-amiens.fr Principal Investigator: Bruno CHAUFFERT Sub-Investigator: Roxana FOURNIER Sub-Investigator: Sanaa HANNAT CH Victor Dupouy Recruiting Argenteuil, France Contact: Malika BOUDRAOUI malika_boudraoui@yahoo.fr Principal Investigator: Malika BOUDRAOUI Sub-Investigator: Radu VANICA Sub-Investigator: Arnaud BOUTANT-LAROZE Sub-Investigator: Laëticia JOLY Sub-Investigator: Julie BOISSET Sub-Investigator: Djamel GHEBRIOU Hôpital privé Les Bonnettes Recruiting Arras, France Contact: Bruno HUGUENIN drbhuguenin@orange.fr Principal Investigator: Bruno HUGUENIN Sub-Investigator: Anne-Sophie BLANC CH Recruiting Auch, France Contact: Karine SALIGNON K.Salignon@ch-auch.fr Principal Investigator: Karine SALIGNON CH Recruiting Auxerre, France Contact: Anne-Laure VILLING alvilling@ch-auxerre.fr Principal Investigator: Anne-Laure VILLING Clinique Tivoli Ducos Recruiting Bordeaux, France Contact: Nathalie BONICHON-LAMICHHANE bonichon-lamichhane@wanadoo.fr Principal Investigator: Nathalie BONICHON-LAMICHHANE Polyclinique Nord Recruiting Bordeaux, France Contact: Cédric LECAILLE lecail@hotmail.com Principal Investigator: Cédric LECAILLE Sub-Investigator: Xavier MONCOUCY Sub-Investigator: Regis MANNANT Sub-Investigator: Iris DEVAURE Sub-Investigator: Laure DUPONT KAZMA CH Dubois Recruiting Brive La Gaillarde, France Contact: Laure VAYRE laure.vayre@ch-brive.fr Principal Investigator: Laure VAYRE Centre François Bacless Recruiting Caen, France Contact: Aurélie PARZY a.parzy@baclesse.unicancer.fr Principal Investigator: Aurélie PARZY Hôpital privé Sainte Marie Recruiting Chalon sur Saone, France Contact: Adrien MELIS melisadrien@yahoo.fr Principal Investigator: Adrien MELIS Sub-Investigator: Erika VIEL Sub-Investigator: André VANOLI Sub-Investigator: Léa PERRON Centre Oncologie et Radiothérapie Recruiting Dijon, France Contact: Ariane DARUT JOUVE ariane.jouve@orange.fr Principal Investigator: Ariane DARUT JOUVE Sub-Investigator: Genevieve BOILLEAU-JOLIMOY Sub-Investigator: Marie-Christine BONE-LEPINOY Sub-Investigator: Edouard LAGNEAU CHI Recruiting Elbeuf, France Contact: Anne-Marie QUEUNIET anne-marie.queuniet@chi-elbeuf-louviers.fr Principal Investigator: Anne-Marie QUEUNIET CH Marne La Vallée Recruiting Jossigny, France Contact: Christine LE FOLL clefoll@ch-lagny77.fr Principal Investigator: Christine LE FOLL Sub-Investigator: Tamar KUTATELADZE CHD Les Oudairies Recruiting La Roche sur Yon, France Contact: Roger FAROUX roger.faroux@chd-vendee.fr Principal Investigator: Roger FAROUX Sub-Investigator: Morgane AMIL Sub-Investigator: Lucile BAUGUION Sub-Investigator: Cécile GARCEAU Sub-Investigator: Carelle KOUDOUGOU Sub-Investigator: Vincent MACE Sub-Investigator: Matthieu SCHNEE Sub-Investigator: Véronique GIRRE Sub-Investigator: Tifenn L'HARIDON Sub-Investigator: Frank PRIOU Sub-Investigator: Jean-François RAMEE Sub-Investigator: Thierry CHARLOIS Sub-Investigator: Elodie MENAGER TABOUREL Clinique du Cap d'Or Recruiting La Seyne Sur Mer, France Contact: Mounira EL DEMERY oncocco2@gmail.com Principal Investigator: Mounira EL DEMERY Caluire et Cuire - Infirmerie Protestante de Lyon Recruiting Lyon, France Contact: Johannes HARTWIG johannes.hartwig@infirmerie-protestante.com Principal Investigator: Johannes HARTWIG Sub-Investigator: David TAVAN CH Lyon Sud (HCL) - Pierre Benite Recruiting Lyon, France Contact: Claire FALANDRY claire.falandry@chu-lyon.fr Principal Investigator: Claire FALANDRY Sub-Investigator: Marion CHAUVENET Sub-Investigator: Benoît YOU Hôpital privé Jean Mermoz Recruiting Lyon, France Contact: Jérôme DESRAME jerome.desrame@orange.fr Principal Investigator: Jérôme DESRAME Sub-Investigator: Pascal ARTRU Sub-Investigator: Gérard LLEDO Hôpital Européen Recruiting Marseille, France Contact: Yves RINALDI y.rinaldi@hopital-europeen.fr; yrinaldi@wanadoo.fr Principal Investigator: Yves RINALDI Sub-Investigator: Julie GIGOUT Sub-Investigator: Cécile JULIEN CH Recruiting Meaux, France Contact: Christophe LOCHER c-locher@ch-meaux.fr Principal Investigator: Christophe LOCHER Sub-Investigator: Laurence THOMAS-MARQUES Sub-Investigator: Marc PRIETO Sub-Investigator: Hatem SALLOUM CHRU - Hôpital Saint Eloi Recruiting Montpellier, France Contact: Eric ASSENAT e-assenat@chu-montpellier.fr;e.assenat@gmail.com Principal Investigator: Eric ASSENAT Sub-Investigator: Christophe CARENCO Sub-Investigator: Thibault MAZARD Sub-Investigator: Marc YCHOU Sub-Investigator: Catherine GUILLEMARE Clinique d'Occitanie Recruiting Muret, France Contact: Jean-Marie VANTELON jmvantelon@gmail.com Principal Investigator: Jean-Marie VANTELON Hôpital Américain Recruiting Neuilly sur Seine, France Contact: Lionel VEDRINE lionelvedrine@orange.fr Principal Investigator: Lionel VEDRINE Sub-Investigator: Hanah LAMALLEM Sub-Investigator: Marc BOLLET Sub-Investigator: Alain TOLEDANO CHR - Service HGE Recruiting Orléans, France Contact: Barbara DAUVOIS barbara.dauvois@chr-orleans.fr Principal Investigator: Barbara DAUVOIS Sub-Investigator: Jean-Paul LAGASSE Sub-Investigator: Sofia HERRMANN Sub-Investigator: Belinda TCHOUNJEU Saint Joseph Recruiting Paris, France Contact: Nabil BABA HAMED nbaba-hamed@hpsj.fr Principal Investigator: Nabil BABA HAMED Sub-Investigator: Robert SVERDLIN Sub-Investigator: Francesco SAVINELLI Sub-Investigator: Michel GATINEAU Sub-Investigator: Lionel STAUDACHER Sub-Investigator: Eric RAYMOND CH Recruiting Perpignan, France Contact: Faiza KHEMISSA AKOUZ faiza.khemissa@ch-perpignan.fr Principal Investigator: Faiza KHEMISSA AKOUZ Hôpital Haut Leveque Recruiting Pessac, France Contact: Eric TERREBONNE eric.terrebonne@chu-bordeaux.fr Principal Investigator: Eric TERREBONNE Sub-Investigator: Pierre GROUSSEAU Sub-Investigator: Denis SMITH Centre Cario - HPCA Recruiting Plérin, France Contact: Pierre Luc ETIENNE pl.etienne@cario-sante.fr ; pl.etienne@wanadoo.fr Principal Investigator: Pierre Luc ETIENNE Sub-Investigator: Dominique BESSON Sub-Investigator: ANNE-CLAIRE HARDY-BESSARD CH Annecy Genevois Recruiting Pringy, France Contact: Emmanuel MAILLARD emaillard@ch-annecygenevois.fr Principal Investigator: Emmanuel MAILLARD Sub-Investigator: Mathieu BACONNIER Sub-Investigator: Aude MONTCHAUD Sub-Investigator: Laëtitia STEFANI Sub-Investigator: Oana POP CHU Recruiting Saint-Etienne, France Contact: Jean-Marc PHELIP j.marc.phelip@chu-st-etienne.fr Principal Investigator: Jean-Marc PHELIP Sub-Investigator: Nadia BOUARIOUA Sub-Investigator: Léa CLAVEL CHP Recruiting Saint-Grégoire, France Contact: Laurent MIGLIANICO lmiglianico@cpa-sante.com Principal Investigator: Laurent MIGLIANICO Sub-Investigator: Anne MERCIER-BLAS Sub-Investigator: Jerome CHAMOIS Sub-Investigator: Romuald LE SCODAN Centre Paul Strauss Recruiting Strasbourg, France Contact: Meher BEN ABDELGHANI mbenabdelghani@strasbourg.unicancer.fr Principal Investigator: Meher BEN ABDELGHANI Sub-Investigator: Pascal PIEDBOIS Sub-Investigator: Christian BOREL Sub-Investigator: Christine BELLETIER CHI Les Hôpitaux de Léman Recruiting Thonon Les Bains, France Contact: Ahmed BEDJAOUI a-bedjaoui@ch-hopitauxduleman.fr Principal Investigator: Ahmed BEDJAOUI Sub-Investigator: Maria DIAZ-GHANEM Hôpital privé Recruiting Villeneuve D'Ascq, France Contact: Olivier ROMANO romanoolivier@yahoo.fr Principal Investigator: Olivier ROMANO Sub-Investigator: Nathalie LEMOINE Less <<
NCT02386397	Digestive Cancer	Phase 1 Phase 2	Recruiting	April 2019	France ... More >> Centre Val d'Aurelle Recruiting Montpellier, France, 34298 Principal Investigator: Eric ASSENAT, MD Less <<
NCT02368886	Colon Adenocarcinoma ... More >> Rectal Adenocarcinoma Stage III Colorectal Cancer AJCC v7 Stage IIIA Colorectal Cancer AJCC v7 Stage IIIB Colorectal Cancer AJCC v7 Stage IIIC Colorectal Cancer AJCC v7 Stage IV Colorectal Cancer AJCC v7 Stage IVA Colorectal Cancer AJCC v7 Stage IVB Colorectal Cancer AJCC v7 Less <<	Phase 2	Active, not recruiting	June 22, 2019	-
NCT01298570	-		Active, not recruiting	-	-
NCT03564938	Colorectal Neoplasms	Phase 4	Recruiting	October 19, 2020	India ... More >> HCG-City Cancer Centre Not yet recruiting Vijayawada, Andhra Pradesh, India, 520004 BLK Super Speciality Hospital Not yet recruiting New Delhi, Delhi, India, 11005 Sir Ganga Ram Hospital Not yet recruiting New-Delhi, Delhi, India, 110060 The Gujarat Cancer & Research Institute Not yet recruiting Ahmedabad, Gujarat, India, 380016 Manipal Hospital Not yet recruiting Bangalore, Karnataka, India, 560017 Healthcare Global Enterprises Ltd Not yet recruiting Bangalore, Karnataka, India, 560027 Tata Memorial Hospital Recruiting Mumbai, Maharashtra, India, 400012 Fortis Hospital Not yet recruiting West-Mumbai, Maharashtra, India, 400078 Health Point Hospital Not yet recruiting Kolkata, West Bengal, India, 700025 Indraprastha Apollo Hospital Not yet recruiting New Delhi, India Less <<
NCT01265979	-		Completed	-	Belgium ... More >> Radiology Department Leuven, Belgium, 3000 Less <<
NCT01298570	Colorectal Cancer Metastatic	Phase 2	Active, not recruiting	February 2019	United States, Colorado ... More >> Rocky Mountain Cancer Centers Denver, Colorado, United States, 80218 United States, Florida Mount Sinai Medical Center-Miami Miami, Florida, United States, 33140 Moffitt Cancer Center Tampa, Florida, United States, 33612 United States, Georgia Emory University Atlanta, Georgia, United States, 30322 Georgia Cancer Specialists Atlanta, Georgia, United States, 30341 United States, Indiana Indiana University Simon Cancer Center Indianapolis, Indiana, United States, 46202 United States, Kentucky University of Louisville James Brown Cancer Center Louisville, Kentucky, United States, 40202 United States, New York North Shore Long Island Jewish Health System Manhasset, New York, United States, 11030 New York University Langone Medical Center New York, New York, United States, 10016 United States, North Carolina Seby B. Jones Cancer Center Boone, North Carolina, United States, 28607 University of North Carolina Chapel Hill, North Carolina, United States, 27599 Carolinas HealthCare System Charlotte, North Carolina, United States, 28262 Southeast Medical Oncology Center Goldsboro, North Carolina, United States, 27534 The Moses Cone Regional Cancer Center Greensboro, North Carolina, United States, 27403 Leo W. Jenkins Cancer Center at ECU Medical School Greenville, North Carolina, United States, 27834 First Health of the Carolinas, Moore Regional Hospital Pinehurst, North Carolina, United States, 28374 Rex Cancer Center at Rex Hospital Raleigh, North Carolina, United States, 27607 Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 United States, Ohio University of Cincinnati Cincinnati, Ohio, United States, 45267 Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43221 United States, Virginia University of Virginia Charlottesville, Virginia, United States, 22903 Portsmouth Naval Medical Center Portsmouth, Virginia, United States, 23708 United States, Washington Multicare Regional Cancer Center Tacoma, Washington, United States, 98405 Ireland Ireland Cooperative Clinical Research Group Dublin, Ireland Less <<
NCT01896856	Previously Treated Metastatic ... More >>Colorectal Cancer Less <<	Phase 2	Recruiting	September 2019	United States, California ... More >> USC / Norris Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90033 Contact: Anthony El-Khoueiry, MD 323-865-3967 elkhouei@med.usc.edu United States, Maryland Sidney Kimmel Comprehensive Cancer Center Recruiting Baltimore, Maryland, United States, 21231 Contact: Ellen Lilly-Foreman, RN 443-287-4961 lillyel@jhmi.edu Contact: Tearra Miles tlawre18@jhmi.edu Principal Investigator: Nilo Azad, MD United States, New York Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Derek Alexander 646-888-1381 alexandd@mskcc.org Principal Investigator: Andrea Cercek, MD Netherlands VU Medisch Centrum Recruiting Amsterdam, Netherlands, 1081 HV Contact: Henk Verheul, MD h.verheul@vumc.nl Contact: Elske Gootjes, MD e.gootjes@vumc.nl Less <<
NCT02835924	Metastatic Colorectal Cancer	PHASE2	COMPLETED	2025-09-19	Spanish Cooperative Group for ... More >>the Treatment of Digestive Tumors, Madrid, 28007, Spain Less <<
NCT03081494	Metastatic Colorectal Cancer	Phase 1	Recruiting	February 28, 2019	Australia, New South Wales ... More >> Novartis Investigative Site Active, not recruiting St Leonards, New South Wales, Australia, 2065 Australia, Western Australia Novartis Investigative Site Active, not recruiting Murdoch, Western Australia, Australia, 6150 Canada, Quebec Novartis Investigative Site Completed Montreal, Quebec, Canada, H3T 1E2 France Novartis Investigative Site Completed Toulouse Cedex 9, France, 31059 Israel Novartis Investigative Site Recruiting Tel Aviv, Israel, 64239 Italy Novartis Investigative Site Withdrawn Milano, MI, Italy, 20162 Novartis Investigative Site Withdrawn Rozzano, MI, Italy, 20089 Japan Novartis Investigative Site Completed Kashiwa, Chiba, Japan, 277-8577 Korea, Republic of Novartis Investigative Site Active, not recruiting Seoul, Korea, Korea, Republic of, 05505 Netherlands Novartis Investigative Site Recruiting Leiden, Netherlands, 2333 ZA Singapore Novartis Investigative Site Completed Singapore, Singapore, 169610 Spain Novartis Investigative Site Completed Barcelona, Catalunya, Spain, 08035 Novartis Investigative Site Terminated Madrid, Spain, 28040 Novartis Investigative Site Completed Madrid, Spain, 28041 Less <<
NCT01959269	-		Completed	-	Germany ... More >> Multiple Locations, Germany Less <<
NCT01786538	Metastatic Colorectal Cancer	Phase 3	Withdrawn	May 2017	Korea, Republic of ... More >> Asan Medical Center Seoul, Songpa-gu, Korea, Republic of, 138736 Less <<
NCT02656524	-		Completed	-	Hungary ... More >> Budapest, Hungary Less <<
NCT03644511	-		Not yet recruiting	December 31, 2021	Germany ... More >> Many Locations Not yet recruiting Multiple Locations, Germany Less <<
NCT02241720	Upper GI Cancer	Phase 2	Terminated(Low Accrual)	-	United States, Utah ... More >> Huntsman Cancer Institute Salt Lake City, Utah, United States, 84112 Less <<
NCT02584465	Ovarian Carcinoma	Phase 2	Recruiting	May 2022	France ... More >> ICO Paul Papin Active, not recruiting Angers, France, 49100 Institut Sainte-Catherine Active, not recruiting Avignon, France, 84918 Hôpital Jean Minjoz Active, not recruiting Besancon, France, 25030 Institut Bergonié Recruiting Bordeaux, France, 33076 Contact: Anne FLOQUET, MD 5 56 33 33 33 ext 0033 a.floquet@bordeaux.unicancer.fr Polyclinique Bordeaux Nord Active, not recruiting Bordeaux, France, 33300 Centre François Baclesse Enrolling by invitation Caen, France, 14000 Centre Hospitalier de Cholet Active, not recruiting Cholet, France, 49300 Centre Jean Perrin Enrolling by invitation Clermont-ferrand, France, 63000 Centre Oscar Lambret Active, not recruiting Lille, France, 59020 Centre Hospitalier Universitaire Dupuytren Enrolling by invitation Limoges, France, 87042 Centre Léon Bérard Recruiting Lyon, France, 69373 Contact: Olivier TREDAN, MD 4 78 78 59 16 ext 0033 olivier.tredan@lyon.unicancer.fr Institut Paoli Calmettes Recruiting Marseille, France, 13009 Contact: Magali PROVANSAL, MD 4 91 22 37 40 ext 0033 provansalm@ipc.unicancer.fr Hôpital de Mont-de-Marsan Active, not recruiting Mont de Marsan, France, 40024 Centre Azuréen de Cancérologie Recruiting Mougins, France, 06250 Contact: Rémy LARGILLIER 4 92 92 37 37 ext 0033 r.largillier@cac-mougins.fr ORACLE - Centre d'Oncologie de Gentilly Active, not recruiting Nancy, France, 54100 Centre Catherine de Sienne Recruiting Nantes, France, 44202 Contact: Alain LORTHOLARY, MD 2 28 27 21 71 ext 0033 lortholary.alain@catherinedesienne.fr Centre Hospitalier Régional d'Orléans Active, not recruiting Orléans, France, 45067 Institut Mutualiste Montsouris Recruiting Paris, France, 75014 Contact: Chrostophe LOUVET, MD 1 56 61 60 35 ext 0033 christophe.louvet@imm.fr Clinique Francheville Active, not recruiting Perigueux, France, 24004 Centre Hospitalier Lyon Sud Active, not recruiting Pierre-Benite, France, 69495 Centre CARIO - HPCA Recruiting Plerin SUR MER, France, 22190 Contact: Anne-Claire HARDY-BESSARD, MD 2 96 75 22 16 ext 0033 ac.hardy@clin-armoricaine.fr Centre Hospitalier Annecy Genevois Active, not recruiting Pringy, France, 74374 Institut Jean Godinot Recruiting Reims, France, 51056 Contact: Aude-Marie SAVOYE, MD 26 50 43 97 ext +33(0)4 aude-marie.savoye@reims.unicancer.fr ICO Centre René Gauducheau Active, not recruiting Saint-herblain, France, 44805 Centre de Radiothérapie - Clinique Sainte-Anne Active, not recruiting Strasbourg, France, 67000 Centre Paul Strauss Active, not recruiting Strasbourg, France, 67065 Centre Hospitalier Universitaire Bretonneau Active, not recruiting Tours, France, 37044 Less <<
NCT02389244	Ewing Sarcomas ... More >> Chondrosarcomas Osteosarcomas Chondroma Less <<	Phase 2	Recruiting	March 2021	France ... More >> Hopital Jean Monjoz Not yet recruiting Besancon, France, 25030 Principal Investigator: Elsa KALBACHER, MD Institut Bergonie Recruiting Bordeaux, France, 33076 Principal Investigator: Antoine ITALIANO, MD Centre Francois Baclesse Recruiting Caen, France, 14176 Principal Investigator: Corinne DELCAMBRE, MD Centre Georges Francois Leclerc Recruiting Dijon, France, 21079 Principal Investigator: Nicolas ISAMBERT, MD Centre Oscar Lambret Recruiting Lille, France, 59020 Principal Investigator: Nicolas PENEL, MD Centre Léon Berard Recruiting Lyon, France, 69373 Principal Investigator: Jean Yves BLAY, MD PhD Institut Paoli Calmettes Recruiting Marseille, France, 13273 Principal Investigator: François BERTUCCI, MD PhD La Timone University Hospital Recruiting Marseille, France, 13385 Principal Investigator: Florence DUFFAUD, MD PhD ICM Val d'Aurelle Recruiting Montpellier, France, 34298 Principal Investigator: Didier CUPISSOL, MD Centre Antoine Lacassagne Recruiting Nice, France, 06189 Principal Investigator: Antoine THYSS, MD PhD Hôpital Cochin Recruiting Paris, France, 75014 Principal Investigator: Pascaline BOUDOU-ROUQUETTE, MD Institut Curie Recruiting Paris, France Principal Investigator: Sophie PIPERNO-NEUMANN, MD Centre Eugene Marquis Recruiting Rennes, France, 35042 Principal Investigator: Christophe PERRIN, MD Institut de cancerologie de l'ouest site Rene Gauducheau Recruiting Saint Herblain, France, 44805 Principal Investigator: Emmanuelle BOMPAS, MD Institut de Cancérologie Lucien Neuwirth (ICLN) Recruiting Saint Priest en Jarez, France, 42270 Principal Investigator: Olivier COLLARS, MD Institut Claudius Regaud Recruiting Toulouse, France, 31052 Principal Investigator: Christine CHEVREAU, MD CHU Bretonneau Recruiting Tours, France, 37000 Principal Investigator: Helene VEGAS, MD Institut de cancerologie de lorraine alexis Vautrin Recruiting Vandoeuvre les Nancy, France, 54519 Principal Investigator: Maria RIOS, MD Gustave Roussy Recruiting Villejuif, France, 94800 Principal Investigator: Olivier MIR, MD Less <<
NCT02234180	-		Terminated	-	-
NCT02234180	Adenocarcinoma of the Gastroes... More >>ophageal Junction Stage IIB Esophageal Adenocarcinoma Stage IIIA Esophageal Adenocarcinoma Stage IIIB Esophageal Adenocarcinoma Stage IIIC Esophageal Adenocarcinoma Less <<	Phase 2	Terminated	-	United States, Illinois ... More >> Carle Cancer Center Urbana, Illinois, United States, 61801 United States, Kansas Cancer Center of Kansas - Wichita Wichita, Kansas, United States, 67214 United States, Louisiana Ochsner Medical Center Jefferson New Orleans, Louisiana, United States, 70121 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Nebraska Missouri Valley Cancer Consortium Omaha, Nebraska, United States, 68106 United States, New Hampshire Dartmouth Hitchcock Medical Center Lebanon, New Hampshire, United States, 03756 United States, New York Memorial Sloan-Kettering Cancer Center New York, New York, United States, 10065 United States, North Carolina Comprehensive Cancer Center of Wake Forest University Winston-Salem, North Carolina, United States, 27157 United States, Ohio Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 Toledo Clinic Cancer Centers-Toledo Toledo, Ohio, United States, 43623 Less <<
NCT01339104	Neoplasms	Phase 1	Completed	-	United States, Colorado ... More >> Aurora, Colorado, United States, 80010 United States, Michigan Ann Arbor, Michigan, United States, 48109 United States, Missouri St. Louis, Missouri, United States, 63110 United States, Oklahoma Oklahoma City, Oklahoma, United States, 73104 United States, Tennessee Nashville, Tennessee, United States, 37203 United States, Washington Seattle, Washington, United States, 98109 Less <<
NCT01774344	Carcinoma, Hepatocellular	Phase 3	Active, not recruiting	February 28, 2019	-
NCT02241720	-		Terminated(Low Accrual)	-	-
NCT01913639	Esophageal Cancer ... More >> Gastric Cancer Less <<	Phase 2	Active, not recruiting	July 2019	United States, New Jersey ... More >> Memoral Sloan Kettering Cancer Center Basking Ridge, New Jersey, United States United States, New York Memorial Sloan Kettering Cancer Center @ Suffolk Commack, New York, United States, 11725 Memorial Sloan Kettering Cancer Center New York, New York, United States, 10065 Memorial Sloan Kettering at Mercy Medical Center Rockville Centre, New York, United States Memoral Sloan Kettering Cancer Center@Phelps Memorial Hospital Sleepy Hollow, New York, United States Less <<
NCT03305913	Pretreated Metastatic Colorect... More >>al Cancer Less <<	Phase 1	Recruiting	June 30, 2019	Germany ... More >> Universitätsmedizin Mainz, I.Medizinische Klinik und Poliklinik Recruiting Mainz, Germany, 55131 Contact: Markus Möhler, Prof. Dr. Less <<
NCT01774344	-		Active, not recruiting	-	-
NCT02910843	Rectal Cancer	Phase 1	Recruiting	December 2022	Switzerland ... More >> St. Claraspital Basel Recruiting Basel, Switzerland, 4016 Contact: Dieter Köberle, MD +41 61 685 85 85 dieter.koeberle@claraspital.ch Principal Investigator: Dieter Köberle, MD Universitätsspital Basel Recruiting Basel, Switzerland, 4031 Contact: Viviane Hess, Prof +41 61 265 50 74 viviane.hess@usb.ch Principal Investigator: Viviane Hess, Prof Inselspital Bern Recruiting Bern, Switzerland, 3010 Contact: Martin D. Berger, MD +41 31 632 41 14 martin.berger@insel.ch Principal Investigator: Martin D. Berger, MD Kantonsspital Graubünden Recruiting Chur, Switzerland, 7000 Contact: Ioannis Metaxas, MD +41 81 256 66 46 ioannis.metaxas@ksgr.ch Principal Investigator: Ioannis Metaxas, MD Kantonsspital Luzern Recruiting Luzern, Switzerland, 6000 Contact: Ralph Winterhalder, MD +41 41 205 58 75 ralph.winterhalder@ksl.ch Principal Investigator: Ralph Winterhalder, MD Kantonsspital St. Gallen Recruiting St. Gallen, Switzerland, 9007 Contact: Markus Jörger, MD +41 71 494 29 22 markus.joerger@kssg.ch Principal Investigator: Markus Jörger, MD UniversitätsSpital Zürich Recruiting Zurich, Switzerland, 8091 Contact: Bernhard Pestalozzi, Prof +41 (0)44 255 34 40 bernhard.pestalozzi@usz.ch Principal Investigator: Bernhard Pestalozzi, Prof Less <<
NCT02347852	-		Completed	-	Austria ... More >> Klinikum Kreuzschwestern Wels GmbH Multiple Locations, Austria, 4600 Less <<
NCT03099486	Colorectal Cancer	Phase 2	Recruiting	October 22, 2020	United States, Pennsylvania ... More >> Fox Chase Cancer Center Recruiting Philadelphia, Pennsylvania, United States, 19111 Contact: Wafik El-Deiry, MD 215-214-1515 Less <<
NCT01973868	Neoplasms	Phase 1	Completed	-	United States, California ... More >> University of Southern California Los Angeles, California, United States, 90033 United States, Colorado University of Colorado Hospital Aurora, Colorado, United States, 80045 United States, Missouri Washington University School of Medicine Saint Louis, Missouri, United States, 63110 United States, Pennsylvania University of Pittsburgh Medical Center Health System Pittsburgh, Pennsylvania, United States, 15232 Less <<
NCT02619435	Advanced Colorectal Cancer	Phase 2	Recruiting	November 2018	Italy ... More >> AO G. Rummo Not yet recruiting Benevento, Italy Istituto Nazionale Tumori Fondazione G. Pascale Recruiting Napoli, Italy Seconda Università di Napoli Not yet recruiting Napoli, Italy AO S. Carlo Not yet recruiting Potenza, Italy Less <<
NCT02168777	-		Terminated	-	-
NCT02096354	Colorectal Neoplasms	Phase 2	Active, not recruiting	January 2019	United States, California ... More >> UCSD Moores Cancer Center La Jolla, California, United States, 92093 Stanford University Stanford, California, United States, 94305 United States, Hawaii Kaiser Permanete Honolulu, Hawaii, United States, 96819 United States, Maryland Walter Reed National Military Medical Center Bethesda, Maryland, United States, 20889 Aquilino Cancer Center, Maryland Oncology and Hematology PA Rockville, Maryland, United States, 20850 Less <<
NCT03520842	KRAS Gene Mutation ... More >> Metastatic Malignant Neoplasm in the Brain Recurrent Non-Small Cell Lung Carcinoma Stage IV Non-Small Cell Lung Cancer AJCC v7 Less <<	Phase 2	Recruiting	June 1, 2020	United States, California ... More >> Stanford University School of Medicine Recruiting Palo Alto, California, United States, 94304 Contact: Vivian Tsang 650-723-0186 tsangv@stanford.edu Principal Investigator: Sukhmani Padda Less <<
NCT02773524	Gastro-Oesophageal Cancer	Phase 3	Recruiting	December 2021	-
NCT02168777	Neoplasms	Phase 1	Terminated	-	United States, Connecticut ... More >> New Haven, Connecticut, United States, 06510 United States, Michigan Detroit, Michigan, United States, 48201 United States, Missouri Saint Louis, Missouri, United States, 63110 United States, North Carolina Chapel Hill, North Carolina, United States, 27599 United States, Texas Houston, Texas, United States, 77030 Less <<
NCT02406170	Esophageal Neoplasms ... More >> Stomach Neoplasms Neoplasm Metastasis Less <<	Phase 1 Phase 2	Recruiting	April 2019	Netherlands ... More >> Academic Medical Center, Medical Oncology Recruiting Amsterdam, Netherlands, 1100 DD Contact: H WM van Laarhoven, MD, PhD, PhD 31 20 5665955 h.vanlaarhoven@amc.uva.nl Contact: E. H. vandaalen 31 20 5668229 trialmedonc@amc.uva.nl Principal Investigator: H. WM van Laarhoven, MD, PhD, PhD Sub-Investigator: S O. van der Woude, MD Less <<
NCT02175654	Colorectal Neoplasms\|Metastati... More >>c Disease Less <<	PHASE2	TERMINATED	2025-02-16	Spanish Cooperative Group for ... More >>Digestive Tumour Therapy (TTD), Madrid, 28046, Spain Less <<
NCT02001909	Neoplasms	Phase 1	Completed	-	Germany ... More >> Berlin, Germany, 13353 Less <<
NCT02278783	Ovarian Cancer ... More >> Primary Peritoneal Cancer Fallopian Tube Cancer Less <<	Phase 2	Terminated(Slow Accrual)	-	United States, Utah ... More >> Huntsman Cancer Institute Salt Lake City, Utah, United States, 84112 Less <<
NCT02398513	Oncology	Phase 1	Completed	-	China ... More >> Shanghai, China, 200032 Less <<
NCT02199223	KRAS and NRAS Wild-type Colore... More >>ctal Cancer Less <<	Phase 1	Terminated(Slow accrual)	-	United States, Utah ... More >> Huntsman Cancer Institute Salt Lake City, Utah, United States, 84112 Less <<
NCT03465722	GIST	Phase 3	Recruiting	April 2023	-
NCT01875380	Colorectal Neoplasms\|Metastati... More >>c Disease Less <<	PHASE2	COMPLETED	2025-04-16	Spanish Cooperative Group for ... More >>Digestive Tumour Therapy (TTD), Madrid, 28046, Spain Less <<
NCT02098538	Adenoid Cystic Carcinoma	PHASE2	COMPLETED	2024-11-07	Memorial Sloan Kettering Cance... More >>r Center, Basking Ridge, New Jersey, United States\|Memorial Sloan Kettering Cancer Center @ Suffolk, Commack, New York, 11725, United States\|Memorial Sloan Kettering Cancer Center, New York, New York, 10065, United States\|Memorial Sloan Kettering at Mercy Medical Center, Rockville Centre, New York, United States\|Memorial Sloan Kettering Westchester, West Harrison, New York, 10604, United States Less <<
NCT02048722	Adult Angiosarcoma ... More >> Recurrent Adult Soft Tissue Sarcoma Stage III Adult Soft Tissue Sarcoma Stage IV Adult Soft Tissue Sarcoma Less <<	Phase 2	Recruiting	February 2020	United States, California ... More >> Sarcoma Oncology Center Recruiting Santa Monica, California, United States, 90403 Contact: Sant P. Chawla, M.D. FRACP 310-552-9999 Principal Investigator: Sant P. Chawla, M.D. FRACP United States, Florida Mayo Clinic in Florida Recruiting Jacksonville, Florida, United States, 32224-9980 Contact: Steven Attia, DO 904-953-7292 Principal Investigator: Steven Attia, DO United States, Illinois Northwestern University Recruiting Chicago, Illinois, United States, 60611 Contact: Mark Agulnik 312-695-1222 m-agulnik@northwestern.edu Principal Investigator: Mark Agulnik United States, Iowa University of Iowa Recruiting Iowa City, Iowa, United States, 52246 Contact: Mohammed M. Milhem 319-356-2324 mohammed-milhem@uiowa.edu Principal Investigator: Mohammed M. Milhem United States, Minnesota University of Minnesota Medical Center-Fairview Not yet recruiting Minneapolis, Minnesota, United States, 55455 Contact: Keith M. Skubitz 612-625-5109 skubi001@umn.edu Principal Investigator: Keith M. Skubitz Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 Contact: Clinical Trials Referral Office 855-776-0015 Principal Investigator: Scott H. Okuno, MD United States, Missouri Washington University-St. Louis Recruiting Saint Louis, Missouri, United States, 63110 Contact: Brian A. Van Tine, MD, PhD 314-747-8475 Principal Investigator: Brian A. Van Tine Less <<
NCT02287727	Rectal Adenocarcinoma ... More >> Stage IIA Rectal Cancer Stage IIB Rectal Cancer Stage IIC Rectal Cancer Stage IIIA Rectal Cancer Stage IIIB Rectal Cancer Less <<	Phase 2	Withdrawn	-	United States, New York ... More >> Roswell Park Cancer Institute Buffalo, New York, United States, 14263 University of Rochester Medical Center - Wilmont Cancer Institute Rocherster, New York, United States, 14642 United States, Ohio Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 Less <<
NCT02278783	-		Terminated(Slow Accrual)	-	-
NCT02195011	Colorectal Neoplasms	Phase 2	Completed	-	United States, Florida ... More >> Florida Cancer Specialists - North Saint Petersburg, Florida, United States, 33705 United States, Missouri Research Medical Center Kansas City, Missouri, United States, 64132 United States, Tennessee Tennessee Oncology PLLC Nashville, Tennessee, United States, 37203 Less <<
NCT02195011	-		Completed	-	-
NCT02080260	Pancreatic Cancer	Phase 2	Completed	-	United States, North Carolina ... More >> Levine Cancer Institute-Albemarle Albemarle, North Carolina, United States, 28001 Levine Cancer Institute-South Tryon Charlotte, North Carolina, United States, 28203 Levine Cancer Institute Charlotte, North Carolina, United States, 28204 Levine Cancer Institute - Pineville Charlotte, North Carolina, United States, 28210 Levine Cancer Institute - Southpark Charlotte, North Carolina, United States, 28211 Levine Cancer Institute - Mallard Creek Charlotte, North Carolina, United States, 28262 Levine Cancer Institute - University Charlotte, North Carolina, United States, 28262 Levine Cancer Institute - Ballantyne Charlotte, North Carolina, United States, 28277 Levine Cancer Institute - Concord Concord, North Carolina, United States, 28025 Levine Cancer Institute-Monroe Monroe, North Carolina, United States, 28112 Levine Cancer Institute - Cleveland Shelby, North Carolina, United States, 28150 United States, South Carolina Low Country Hematology Oncology Charleston, South Carolina, United States, 29406 Less <<
NCT03698253	Colorectal Cancer	Not Applicable	Completed	-	Taiwan ... More >> Chung-Ho Memorial Hospital, Kaohsiung Medical University: Kaohsiung, Taiwan, 807 Less <<
NCT02383433	Metastatic Pancreatic Adenocar... More >>cinoma Less <<	Phase 2	Active, not recruiting	September 1, 2019	United States, Ohio ... More >> Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center Cleveland, Ohio, United States, 44195 Less <<
NCT01068769	-		Active, not recruiting	-	-
NCT01068769	Gastrointestinal Stromal Tumor	Phase 2	Active, not recruiting	December 2018	United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 United States, Oregon Oregon Health Sciences University Portland, Oregon, United States, 97239 United States, Pennsylvania Fox Chase Cancer Center Philadelphia, Pennsylvania, United States, 19111 Less <<
NCT02501551	Melanoma	Phase 2	Recruiting	June 2019	Korea, Republic of ... More >> Severance Hospital, Yonsei University Health System Recruiting Seoul, Korea, Republic of, 120-752 Contact: Sang Joon Shin Less <<
NCT03289273	-		Recruiting	October 1, 2022	-
NCT02638766	Gastrointestinal Stromal Tumor... More >>s Less <<	Phase 2	Recruiting	November 2020	Italy ... More >> Policlinico San Orsola Malpighi Not yet recruiting Bologna, Italy Principal Investigator: Guido Biasco A. O. Careggi Not yet recruiting Firenze, Italy Principal Investigator: Silvia Gasperoni Fondazione IRCCS Istituto Dei Tumori di Milano Not yet recruiting Milan, Italy Principal Investigator: Paolo G. Casalli Istituto Clinico Humanitas Milano Not yet recruiting Milan, Italy Principal Investigator: Armando Santoro Istituto Nazionale Tumori IRCSS "Fondazione G. Pascale" Not yet recruiting Naples, Italy Principal Investigator: Gaetano Apice A. O. Universitaria Policlinico Paolo Giaccone Not yet recruiting Palermo, Italy Principal Investigator: Giuseppe Badalamenti Policlinico Universitario Campus Bio-Medico Not yet recruiting Roma, Italy Principal Investigator: Bruno Vincenzi Istituto di Candiolo - IRCSS Not yet recruiting Torino, Italy Principal Investigator: Giovanni Grignani Spain Hospital Universitario de Canarias Recruiting La Laguna, Santa Cruz de Tenerife, Spain, 38320 Principal Investigator: Claudia Valverde, MD Hospital de Cruces Not yet recruiting Barakaldo, Spain, 48902 Principal Investigator: Natalia Fuente, MD Hospital Universitario Vall d´hebron Recruiting Barcelona, Spain, 08035 Principal Investigator: Claudia Valverde, MD Hospital de la Santa Creu i Sant Pau Recruiting Barcelona, Spain, 08041 Principal Investigator: A. Lopez Pousa, MD Hospital Universitario Gregorio Marañon Not yet recruiting Madrid, Spain, 28009 Principal Investigator: Rosa Alvarez, MD Hospital Universitario La Paz Recruiting Madrid, Spain, 28046 Principal Investigator: Virginia Martinez Marín, MD Hospital Universitario Virgen del Rocío Recruiting Sevilla, Spain, 41013 Principal Investigator: Javier Martín-broto, MD Hospital Universitario Virgen de la Macarena Recruiting Sevilla, Spain, 41071 Principal Investigator: David Vicente Baz, MD Instituto Valenciano de Oncología Not yet recruiting Valencia, Spain, 46009 Principal Investigator: Andres Poveda, MD Hospital Universitario Miguel Servet Not yet recruiting Zaragoza, Spain, 50009 Principal Investigator: Javier Martinez Trufero, MD Less <<
NCT01843400	-		Completed	-	Japan ... More >> Multiple Locations, Japan Less <<
NCT03657641	Colorectal Cancer ... More >> Colorectal Cancer Metastatic Less <<	Phase 1 Phase 2	Not yet recruiting	February 25, 2022	United States, California ... More >> USC / Norris Comprehensive Cancer Center Not yet recruiting Los Angeles, California, United States, 90033 Contact: Xiomara Menendez, RN 323-409-4368 Xiomara.Menendez@med.usc.edu Principal Investigator: Afsaneh Barzi, MD Hoag Memorial Hospital Not yet recruiting Newport Beach, California, United States, 92663 Contact: Alicia L. Bogardus, MA Alicia.bogardus@hoag.org Principal Investigator: Diana L. Hanna, MD United States, Florida Moffitt Cancer Center Not yet recruiting Tampa, Florida, United States, 33612 Contact: Richard D. Kim, MD Richard.Kim@moffitt.org Principal Investigator: Richard D. Kim, MD Less <<
NCT02164240	Gastrointestinal Stromal Tumor	Phase 1	Active, not recruiting	May 2020	United States, Massachusetts ... More >> Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 Less <<
NCT02926222	Glioblastoma Multiforme	Phase 2	Active, not recruiting	October 2018	Italy ... More >> IRCCS "Saverio de Bellis Castellana Grotte, BA, Italy, 70013 Ospedale di Bellaria Bologna, BO, Italy Azienda Ospedaliera "G.Rummo" Benevento, BR, Italy istituto Scientifico Romagnolo per lo Studio e Cura dei Tumori Cesena, FC, Italy, 47014 Istituto Neurologico C. Besta IRCCS Milano, MI, Italy, 20133 Istituto Oncologico Veneto IRCCS, Oncologia Medica 1 Padova, PD, Italy, 35128 Ospedale Santa Chiara Pisa, PI, Italy, 56126 Azienda Ospedaliero Universitaria S. Maria della Misericordia Udine, UD, Italy, 33100 Istituto Nazionale Tumori Regina Elena Roma, Italy, 00144 Azienda Ospedaliera Universitaria Città della Salute e della Scienza Torino, Italy, 10126 Less <<
NCT01900743	Sarcoma	Phase 2	Active, not recruiting	March 31, 2019	Austria ... More >> Medizinische Universität Graz Graz, Austria, 8036 Universitätsklinik für Innere Medizin I Innsbruck, Austria, 6020 LKH Klagenfurt, Austria Krankenhaus der Barmherzigen Schwestern Linz Linz, Austria, 4010 AKH-Wien Wien, Austria, 1090 France Hôpital St Jacques Besancon, France, 25000 Institut Bergonié Bordeaux, France, 33076 Centre François Baclesse Caen, France, 14076 Centre GF Leclercq Dijon, France, 21079 Centre Oscar Lambret Lille, France, 59020 Centre Léon Bérard Lyon, France, 69373 Institut Paoli Calmettes Marseille, France, 13273 Hôpital de La Timone Marseille, France, 13354 Centre René Gauducheau Nantes, France, 44805 Centre Antoine Lacassagne Nice, France, 06189 Institut Curie Paris, France, 75005 Hôpital Saint Louis Paris, France, 75010 Hôpital Cochin Paris, France, 75014 Centre Eugène Marquis Rennes, France, 35042 Centre Henri Becquerel Rouen, France, 76038 Institut Curie - Hôpital René Huguenin Saint Cloud, France, 92210 Institut de Cancérologie Lucien Neuwirth (ICL) St Priest En Jarez, France, 42270 Institut Claudius Regaud Toulouse, France, 32052 Centre Alexis Vautrin Vandoeuvre Les Nancy, France, 54519 Institut Gustave Roussy Villejuif, France, 94800 Less <<
NCT01853046	-		Completed	-	-
NCT01853046	Neoplasms	Phase 1	Completed	-	United States, California ... More >> Los Angeles, California, United States, 90033 United States, Colorado Aurora, Colorado, United States, 80045 United States, Missouri St. Louis, Missouri, United States, 63110 United States, New Hampshire Lebanon, New Hampshire, United States, 03756 United States, New York Buffalo, New York, United States, 14263-0001 Canada, Alberta Edmonton, Alberta, Canada, T6G 1Z2 Canada, British Columbia Vancouver, British Columbia, Canada, V5Z 4E6 Canada, Ontario Hamilton, Ontario, Canada, L8V 5C2 Canada, Quebec Montreal, Quebec, Canada, H2L 4M1 Less <<
NCT02889328	Gastrointestinal Stromal Tumor... More >>s (GISTs) Less <<	PHASE2	COMPLETED	2025-01-18	Asan Medical Center, Universit... More >>y of Ulsan College of Medicine, Seoul, 138-736, Korea, Republic of Less <<
NCT02162914	Cholangiocarcinoma	Phase 2	Unknown	December 2016	Belgium ... More >> CH Jolimont Active, not recruiting Haine-Saint-Paul, Hainaut, Belgium, 7100 University Hospitals of Antwerp Not yet recruiting Antwerp, Belgium, 2650 Contact: Marc Peeters, MD, PhD +32(0)38213954 marc.peeters@uza.be Contact: Iris Verhaegen +32(0)8215681 iris.verhaegen@uza.be Principal Investigator: Marc Peeters, MD, PhD AZ St-Lucas Brugge Not yet recruiting Brugge, Belgium, 8310 Contact: Joris Arts, MD +32(0)50 36 57 11 joris.arts@stlucas.be Contact: Hilde Nevens, Mrs +32(0)50 36 57 11 hilde.nevens@stlucas.be Principal Investigator: Joris Arts, MD Erasme University Hospital Recruiting Brussels, Belgium, 1070 Contact: Anne Demols, MD, PhD +32(0)25555867 anne.demols@erasme.ulb.ac.be Principal Investigator: Anne Demols, MD, PhD Cliniques Universitaires Saint-Luc Recruiting Brussels, Belgium, 1200 Contact: Ivan Borbath, MD, PhD +32 (0)2 764 4213 ivan.borbath@uclouvain.be Contact: Antonino Ceratti, Mr +32 (0)2 764 4213 antonino.ceratti@uclouvain.be Principal Investigator: Ivan Borbath, MD, PhD Grand Hôpital de Charleroi Active, not recruiting Charleroi, Belgium, 6000 AZ St-Lucas Gent Not yet recruiting Gent, Belgium, 9000 Contact: Johan Van Ongeval, MD +32(0)9/2246111 johan.VanOngeval@AZSTLUCAS.be Contact: Koen De Graeve, Mr +32(0)9/224 62 27 koen.degraeve@azstlucas.be Principal Investigator: Johan Van Ongeval, MD UZ Gent Not yet recruiting Gent, Belgium, 9000 Contact: Stéphanie Laurent, MD, PhD 09/3322371 Contact: Roxane Van Vynckt, Mrs +32(0)9/3322378 roxane.vanvynckt@uzgent.be Principal Investigator: Stéphanie Laurent, MD, PhD CHC St-Joseph Active, not recruiting Liège, Belgium, 4000 Hôpital Ambroise Paré Not yet recruiting Mons, Belgium, 7000 Contact: Stephane Holbrechts, MD +32(0)65/39 39 39 stephane.holbrechts@hap.be Contact: Melissa Canzurlo, Mrs +32(0)65/39 39 39 melissa.canzurlo@hap.be Principal Investigator: Stephane Holbrechts, MD AZ Delta Not yet recruiting Roeselare, Belgium, 8800 Contact: Jochen Decaestecker, MD +32(0)51/237111 jdecaestecker@azdelta.be Contact: Sophie Adriaens, Mrs +32(0)51/237111 sadriaens@azdelta.be Principal Investigator: Jochen Decaestecker, MD Less <<
NCT02699073	Metastatic Colorectal Cancer	Phase 2	Recruiting	December 2018	France ... More >> CHU Jean Minjoz Recruiting Besançon, France Contact: Kim STEFANO, MD Hôpitlal Henri Mondor Recruiting Créteil, France Contact: Benoit ROUSSEAU, MD Institut Hospitalier Franco-Britannique Recruiting Levallois Perret, France Contact: Benoist CHIBAUDEL, MD CHRU Claude Huriez Not yet recruiting Lille, France Contact: Mohamed HEBBAR, MD ICM Val D'Aurelle Recruiting Montpellier, France Contact: Thibault MAZARD, MD Hôpital Pitié Salpêtrière Recruiting Paris, France Contact: Jean Baptiste BACHET, MD Hôpital Saint Antoine Recruiting Paris, France Contact: Thierry ANDRE, MD Insitut Mutualiste Montouris Recruiting Paris, France Contact: Jean Luc MOLITOR, MD Less <<
NCT02310477	-		Completed	-	France ... More >> Centre Oscar Lambret Lille, France, 59020 Less <<
NCT01853319	Colorectal Neoplasms	Phase 3	Completed	-	Turkey ... More >> Ankara, Turkey, 06100 Ankara, Turkey, 06500 Antalya, Turkey Balcali/Adana, Turkey, 01330 Bursa, Turkey Gaziantep, Turkey, 27010 Istanbul, Turkey, 34093 Istanbul, Turkey, 34899 Izmir, Turkey, 35100 Kayseri, Turkey Samsun, Turkey Less <<
NCT02023333	Metastatic Colorectal Adenocar... More >>cinoma Less <<	PHASE2	ACTIVE_NOT_RECRUITING	2025-12-25	Memorial Sloan Kettering Cance... More >>r Center at Basking Ridge, Basking Ridge, New Jersey, United States\|Downstate Medical Center, Brooklyn, New York, 11203, United States\|Memorial Sloan Kettering Cancer Center at Commack, Commack, New York, 11725, United States\|Queens Cancer Center of Queens Hospital, Jamaica, New York, 11432, United States\|Memorial Sloan Kettering Cancer Center, New York, New York, 10065, United States\|Memorial Sloan Kettering Cancer Center at Mercy Medical Center, Rockville Centre, New York, 11570, United States\|Memorial Sloan Kettering Cancer Center Sleepy Hollow, Sleepy Hollow, New York, 10591, United States Less <<
NCT02053376	Metastatic Biliary Tract Carci... More >>noma Less <<	PHASE2	COMPLETED	2018-05-14	UPMC Hillman Cancer Center, Pi... More >>ttsburgh, Pennsylvania, 15232, United States Less <<
NCT02800330	Colorectal Neoplasms ... More >> Gastrointestinal Stromal Tumors Less <<	Phase 4	Completed	-	Netherlands ... More >> Erasmus Medical Center Rotterdam, South Holland, Netherlands, 3015 CE Less <<
NCT03475953	Colorectal Cancer Not MSI-H or... More >> MMR-deficient GIST Oesophageal or Gastric Carcinoma Biliary Tract Cancer Hepatocellular Carcinoma Less <<	Phase 1 Phase 2	Recruiting	April 2021	France ... More >> Institut Bergonié Recruiting Bordeaux, France, 33076 Contact: Sophie COUSIN, MD Principal Investigator: Sophie COUSIN, MD Sub-Investigator: Antoine ITALIANO, MD, PhD Institut de Cancérologie de Montpellier Not yet recruiting Montpellier, France, 34298 Contact: Antoine ADENIS, MD, PhD IUCT Oncopôle - Institut Claudius Regaud Not yet recruiting Toulouse, France, 31059 Contact: Carlos GOMEZ-ROCA, MD Less <<
NCT02259725	Gastrinoma Gl... More >>ucagonoma Insulinoma Metastatic Gastrointestinal Carcinoid Tumor Pancreatic Polypeptide Tumor Pulmonary Carcinoid Tumor Recurrent Gastrointestinal Carcinoid Tumor Recurrent Islet Cell Carcinoma Somatostatinoma Less <<	Phase 2	Recruiting	August 16, 2020	United States, Arizona ... More >> Mayo Clinic in Arizona Not yet recruiting Scottsdale, Arizona, United States, 85259 Contact: Thorvardur R. Halfdanarson 507-538-7623 Halfdanarson.Thorvardur@mayo.edu Principal Investigator: Thorvardur R. Halfdanarson United States, California USC Norris Comprehensive Cancer Center Recruiting Los Angeles, California, United States, 90033 Contact: Dana Agafitei 323-865-0467 Raluca.Agafitei@med.usc.edu Principal Investigator: Syma Iqbal Hoag Memorial Hospital Presbyterian Recruiting Newport Beach, California, United States, 92663 Contact: Alicia Bogardus, MA 949-764-6755 Alicia.bogardus@hoag.org Principal Investigator: Diana Hanna, MD USC Norris Oncology Hematology‐Newport Beach Recruiting Newport Beach, California, United States, 92663 Contact: Kristy Massopust 949-474-5733 Kristy.Massopust@med.usc.edu Principal Investigator: Greg Angstreich, MD United States, Washington Seattle Cancer Care Alliance Not yet recruiting Seattle, Washington, United States, 98109 Contact: William P. Harris 206-688-7175 wph3@u.washington.edu Principal Investigator: William P. Harris Less <<
NCT03010722	Metastatic Colorectal Cancer		COMPLETED	2025-07-17	The Royal Marsden NHS Foundati... More >>on Trust London and Surrey, Carshalton, Surrey, SM2 5PT, United Kingdom Less <<
NCT02466009	Metastatic Colorectal Cancer	PHASE2	COMPLETED	2022-03-09	Mayo Clinic, Rochester, Minnes... More >>ota, 55901, United States\|University of Rochester, Rochester, New York, 14642, United States\|University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, 27514, United States\|Fox Chase Cancer Center, Philadelphia, Pennsylvania, 19111, United States Less <<
NCT02606097	Gastrointestinal Stromal Tumou... More >>r (GIST) Less <<	Phase 2	Unknown	-	Taiwan ... More >> Chang Gung Memorial Hospital Recruiting Taoyuan, Taiwan, 333 Contact: Chun-Nan Yeh, MD 886-3-3281200 ext 3219 yehchunnan@gmail.com Less <<
NCT01996969	Metastatic Colorectal Cancer		COMPLETED	2025-05-16	Seoul National University Hosp... More >>ital, Seoul, 110-744, Korea, Republic of Less <<
NCT03627728	Gastric Cancer	Phase 2	Recruiting	December 2021	Italy ... More >> Struttura Complessa di OncologiaIRCCS- Istituto in Tecnologie Avanzate e Modelli Assistenziali in Oncologia Arcispedale Santa Maria Nuova Recruiting Reggio Emilia, Italy, 42123 Contact: gnoni roberta, biologist +390522295181 gnoni.roberta@ausl.re.it Less <<
NCT02116894	Colorectal Cancer	Phase 1	Completed	-	United States, North Carolina ... More >> Duke Cancer Center, Duke University Medical Center Durham, North Carolina, United States, 27710 Less <<
NCT02465502	Colorectal Neoplasms	Phase 2	Completed	-	Brazil ... More >> São Paulo, Brazil, 01246000 Less <<
NCT02459119	Urothelial Cancer (Urinary Bla... More >>dder, Ureters, or Renal Pelvis Cancer) Less <<	PHASE2	COMPLETED	2025-04-20	University of Alabama at Birmi... More >>ngham, Birmingham, Alabama, 35294, United States\|Wayne State University, Detroit, Michigan, 48201-2013, United States\|Cleveland Clinic, Cleveland, Ohio, 44195, United States Less <<
NCT02095054	Advanced Cancers	Phase 1	Active, not recruiting	March 2023	United States, Texas ... More >> University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 Less <<
NCT02664077	Stage III (IIIB or IIIC) Colon... More >> Cancer Less <<	Phase 3	Active, not recruiting	October 2019	-
NCT01933958	-		Recruiting	January 30, 2021	Japan ... More >> Recruiting Multiple Locations, Japan Less <<
NCT02425683	Colorectal Neoplasms\|Adenocarc... More >>inoma of the Colon\|Adenocarcinoma of the Rectum Less <<	PHASE2	TERMINATED	2017-09-21	24 Sites, Including Dallas, TX... More >>, Ocala, FL, Denver, CO, Florida, United States Less <<
NCT02115542	Cancer of the Bile Duct	PHASE2	COMPLETED	2021-09-20	H. Lee Moffitt Cancer Center a... More >>nd Research Institute, Tampa, Florida, 33612, United States\|UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, 27514, United States\|VCU Massey Cancer Center, Richmond, Virginia, 23298, United States Less <<
NCT02581059	Colorectal Cancer ... More >> Palliative Medicine Supportive Care Less <<	Phase 2	Terminated(Funder terminated.)	-	United States, Indiana ... More >> Indiana Univeristy Melvin and Bren Simon Cancer Center Indianapolis, Indiana, United States, 46202 IU Health Central Indiana Cancer Centers Indianapolis, Indiana, United States, 46219 United States, New Jersey Altantic Health System Morristown, New Jersey, United States, 07960 United States, North Carolina Comprehensive Cancer Center at Wake Forest Baptist Winston-Salem, North Carolina, United States, 27157 United States, Pennsylvania Gettysburg Cancer Center Gettysburg, Pennsylvania, United States, 17325 Less <<
NCT02402036	Colon Cancer	PHASE2	TERMINATED	2025-11-17	Georgetown University, Washing... More >>ton, District of Columbia, 20007, United States Less <<
NCT02736305	Ovarian Neoplasms	PHASE2	COMPLETED	2019-11-18	National Cancer Centre Singapo... More >>re, Singapore, 169610, Singapore Less <<
NCT02657551	Thyroid Cancer	PHASE2	ACTIVE_NOT_RECRUITING	2025-12-24	Yale Cancer Center, New Haven,... More >> Connecticut, 06520-8028, United States\|Dana-Farber Cancer Institute, Boston, Massachusetts, 02115, United States Less <<
NCT03712943	Colorectal Cancer ... More >> Metastatic Colorectal Cancer Colon Cancer Less <<	Phase 1	Recruiting	October 2022	United States, Florida ... More >> H. Lee Moffitt Cancer Center and Research Institute Recruiting Tampa, Florida, United States, 33612 Contact: Taymeyah E Al-Toubah 813-745-6454 Taymeyah.Al-Toubah@moffitt.org Principal Investigator: Dae W Kim, MD Sub-Investigator: Richard Kim, MD Less <<
NCT02175095	Colorectal Cancer	Not Applicable	Active, not recruiting	April 2018	Korea, Republic of ... More >> Asan Medical Center Seoul, Songpa, Korea, Republic of, 138736 Less <<
NCT01929616	Advanced Chemorefractory Color... More >>ectal Adenocarcinoma Less <<	Phase 2	Active, not recruiting	May 2017	Belgium ... More >> UZA Antwerpen, Edegem, Belgium, 2650 Jules Bordet Institute Brussels, Belgium, 1000 Hopital Erasme Brussels, Belgium, 1070 Cliniques Universitaires Saint Luc Brussels, Belgium Grand Hopital de Charleroi Charleroi, Belgium, 6000 UZ Ghent Ghent, Belgium AZ groeninge Kortrijk, Belgium, 8500 Centre Hospitalier Universitaire de Liège Liège, Belgium, 4000 Clinique St Joseph Liège, Belgium, 4000 Centre hospitalier de Jolimont Lobbes, Belgium, 6540 CHU Ambroise Paré Mons, Belgium, 7000 Centre Hospitalier Régional de Namur Namur, Belgium, 5000 Clinique et Maternité Sainte Elisabeth Namur, Belgium, 5000 Clinique Saint Pierre Ottignies, Belgium, 1340 Hartziekenhuis Roeselare-Menen (HHRM) Roeselare, Belgium, 8800 AZ Turnhout Turnhout, Belgium, 2300 Cliniques Universitaires UCL de Mont-Godinne Yvoir, Belgium, 5530 Less <<
NCT03406871	Advanced and Metastatic Solid ... More >>Tumor Less <<	Phase 1 Phase 2	Recruiting	July 31, 2022	Japan ... More >> NationalCCHE Recruiting Kashiwa, Chiba, Japan, 277-8577 Contact: Kohei Shitara, Dr +81-4-7133-1111 ext 91520 kshitara@east.ncc.go.jp Contact: Shota Fukuoka, DR +81-4-7133-1111 ext 91283 shfukuok@east.ncc.go.jp Less <<
NCT01949194	Metastatic Colorectal Cancer	PHASE2	UNKNOWN	2025-12-18	The Moncton Hospital (Horizon ... More >>Health Network), Moncton, New Brunswick, E1C 6Z8, Canada\|Jewish General Hospital, Montreal, Quebec, H3T 1E2, Canada\|St-Mary's Hospital Centre, Montreal, Quebec, H3T 1M5, Canada\|McGill University Health Centre, Montréal, Quebec, H4A 3J1, Canada\|Hopital Maisonneuve-Rosemont, Montreal, H1T 2M4, Canada Less <<
NCT02466802	Solid Tumor	Phase 1	Active, not recruiting	June 30, 2020	United States, Virginia ... More >> Virginia Commonwealth University/Massey Cancer Center Richmond, Virginia, United States, 23298 Less <<
NCT02307500	Pancreas Cancer\|Ovarian Cancer... More >>\|Melanoma\|Sarcoma\|Thymoma Type B3\|Thymoma Type B2\|Thymic Carcinoma Less <<	PHASE2	COMPLETED	2025-08-20	Istituto Clinico Humanitas, Ro... More >>zzano, Milan, 20089, Italy Less <<
NCT03722108	Adenocarcinoma of the Stomach ... More >> Adenocarcinoma of the Gastroesophageal Junction Less <<	Phase 1 Phase 2	Not yet recruiting	November 2023	France ... More >> Institut du Cancer Montpellier Not yet recruiting Montpellier, France, 34298 Contact: Emmanuelle MD SAMALIN-SCALZI, PhD 33 (0)467612592 emmanuelle@samalin@icm.unicancer.fr Less <<
NCT02651415	Metastatic Colorectal Cancer	Phase 2	Active, not recruiting	August 2018	Canada, British Columbia ... More >> BC Cancer Agency - Vancouver Cancer Centre Vancouver, British Columbia, Canada, V5Z 4E6 Less <<
NCT03042689	Acute Myeloid Leukemia	PHASE1	COMPLETED	2023-02-27	Massachusetts general Hospital... More >>, Boston, Massachusetts, 02114, United States Less <<
NCT02439723	Metastatic Solid Malignancies\|... More >>Locally Advanced Solid Malignancies Less <<	PHASE1	WITHDRAWN	2025-12-17	Cross Cancer Institute, Edmont... More >>on, Alberta, T6G 1Z2, Canada Less <<
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CAS No. :	755037-03-7
Formula :	C₂₁H₁₅ClF₄N₄O₃
M.W :	482.82
SMILES Code :	O=C(NC)C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1
Synonyms :	BAY 73-4506; Fluoro-Sorafenib
MDL No. :	MFCD16038047
InChI Key :	FNHKPVJBJVTLMP-UHFFFAOYSA-N
Pubchem ID :	11167602

GHS Pictogram:
Signal Word:	Warning
Hazard Statements:	H302-H361-H373
Precautionary Statements:	P501-P260-P270-P202-P201-P264-P280-P308+P313-P301+P312+P330-P405

HCT116 cells	40 µM	48 h	Analysis of Regorafenib-induced apoptosis showed that FBW7 wild-type cells were more prone to apoptosis compared to FBW7 mutant cells.	PMC5226932
HCT116 cells	5 µM		Analysis of the effect of Regorafenib on Mcl-1 protein levels showed that Mcl-1 was significantly reduced in FBW7 wild-type cells but not in FBW7 mutant cells.	PMC5226932
Hep3B	1 μM, 2.5 μM, 5 μM, 7.5 μM, 10 μM	72 or 96 h	Regorafenib inhibited the growth of Hep3B cells in a concentration- and time-dependent manner, with an IC50 of 5 μM.	PMC4509637
PLC/PRF/5	1 μM, 2.5 μM, 5 μM, 7.5 μM, 10 μM	72 or 96 h	PLC/PRF/5 cells responded similarly to Hep3B cells.	PMC4509637
HepG2	1 μM, 2.5 μM, 5 μM, 7.5 μM, 10 μM	72 or 96 h	HepG2 cells were more sensitive to Regorafenib, with an approximate IC50 of 1 μM.	PMC4509637
RIL-175 cells	1 µM	36 h	To study the effect of Regorafenib on CXCL10 secretion by RIL-175 cells, results showed that Regorafenib significantly increased CXCL10 secretion	PMC7689089
HCA1 cells	1 µM	36 h	To study the effect of Regorafenib on CXCL10 secretion by HCA1 cells, results showed that Regorafenib increased CXCL10 secretion to a lesser extent	PMC7689089
T24R1 cells	1, 6.25, 12.5, 25, 50 µM	12, 24, 48 h	Regorafenib significantly decreased the viability of T24R1 cells and inhibited the expression of stemness and EMT markers.	PMC10743903
T24R2 cells	1, 6.25, 12.5, 25, 50 µM	12, 24, 48 h	Regorafenib significantly decreased the viability of T24R2 cells and inhibited the expression of stemness and EMT markers.	PMC10743903
SKMEL239 Parental (PAR) cells	2 μM	1 h	inhibit MAPK signaling	PMC8295204
C3 cells	2 μM	1 h	inhibit MAPK signaling	PMC8295204
PC9 cells	2 μM	1 h	inhibit MAPK signaling	PMC8295204

Mice	Acute myeloid leukemia (AML) model	Oral	5 mg/kg	Once daily for 1 month	To evaluate the therapeutic potential of Regorafenib in the AML model, results showed that AML cells in the periphery and spleen were sensitive to treatment, while those in the bone marrow were protected.	PMC5639594
Nude mice	HCT116 xenograft model	Oral	30 mg/kg	10 consecutive days	Evaluation of the antitumor effects of Regorafenib in vivo showed that FBW7 wild-type tumors were more sensitive to Regorafenib, while Mcl-1 degradation was blocked and apoptosis was reduced in FBW7 knockout tumors.	PMC5226932
Mice	HCC model with liver damage	Oral	5, 10, 20 mg/kg	Once daily for 5 days	To study the effect of Regorafenib combined with PD1 blockade on vascular structure and function, antitumor immunity, tumor growth, and survival in HCC mouse models, results showed that 10 mg/kg Regorafenib combined with PD1 blockade significantly improved survival	PMC7689089
Nude mice	T24R1 and T24R2 xenograft tumor model	Intraperitoneal injection	20 mg/kg	20 consecutive days	Regorafenib significantly inhibited the growth of T24R1 and T24R2 xenograft tumors, reduced tumor proliferation and angiogenesis, and promoted tumor cell apoptosis.	PMC10743903
nude mice	BRAF(V600E) CRC tumor models	oral	30 mg/kg	once daily for 40 or 60 days	suppress tumor growth	PMC8295204
Mice	HT-29 and HCT116 human colorectal cancer xenograft models	Oral	30 mg/kg	Once daily for 7 days	To investigate the mechanisms of tumor revascularization after regorafenib withdrawal	PMC8138700

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CAS No.: 755037-03-7

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CAS No.: 755037-03-7

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Preparing Stock Solutions		1mg	5mg	10mg
Preparing Stock Solutions	1 mM 5 mM 10 mM	2.07mL 0.41mL 0.21mL	10.36mL 2.07mL 1.04mL	20.71mL 4.14mL 2.07mL
Dissolving Methods	Animal experiment Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn: in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Protocol 1 Protocol 2

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed