Alternatived Products of [ 7743-29-5 ]
Product Details of [ 7743-29-5 ]
CAS No. : | 7743-29-5 |
MDL No. : | MFCD14525728 |
Formula : |
C29H25BrNO2P
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
530.39
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 7743-29-5 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 7743-29-5 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 7743-29-5 ]
- 1
-
[ 4363-94-4 ]
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[ 7743-29-5 ]
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2-[(Z)-4-(6-Methoxy-quinolin-4-yl)-but-3-enyl]-isoindole-1,3-dione
[ No CAS ]
- 2
-
[ 103854-62-2 ]
-
[ 7743-29-5 ]
-
2-[(Z)-4-(8-Methoxy-quinolin-4-yl)-but-3-enyl]-isoindole-1,3-dione
[ No CAS ]
- 3
-
[ 886498-07-3 ]
-
[ 7743-29-5 ]
-
C19H13BrF3NO3
[ No CAS ]
-
C19H13BrF3NO3
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
|
With potassium carbonate;18-crown-6 ether; In toluene;Reflux; Heating; Inert atmosphere; |
Synthesis of 2a and 2b:A mixture of phosphonium salt 12 (5.24 g, 9.88 mmol), la (or lb) (2.65 g, 9.88 mmol), K2CO3 (1.36 g, 9.88 mmol), and 18-crown-6 (catalytic amount) in toluene (50 mL) was heated at reflux under argon overnight. Upon completion, the mixture was cooled to rt and water was added. The aqueous layer was extracted with ethyl acetate (3 x 75 mL) and the combined organics were dried over Na2S04 and then concentrated. The residue was purified by silica gel chromatography (2: 1 heptane/ethyl acetate). Compound 2a was isolated cleanly as mixture of E and Z isomers (3.78 g, 87% yield). |