Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 79887-14-2 | MDL No. : | MFCD00173880 |
Formula : | C10H10O | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | FRGNOZUOTHMJSC-UHFFFAOYSA-N |
M.W : | 146.19 | Pubchem ID : | 2775124 |
Synonyms : |
|
Num. heavy atoms : | 11 |
Num. arom. heavy atoms : | 6 |
Fraction Csp3 : | 0.2 |
Num. rotatable bonds : | 2 |
Num. H-bond acceptors : | 1.0 |
Num. H-bond donors : | 0.0 |
Molar Refractivity : | 45.68 |
TPSA : | 9.23 Ų |
GI absorption : | High |
BBB permeant : | Yes |
P-gp substrate : | No |
CYP1A2 inhibitor : | Yes |
CYP2C19 inhibitor : | No |
CYP2C9 inhibitor : | No |
CYP2D6 inhibitor : | No |
CYP3A4 inhibitor : | No |
Log Kp (skin permeation) : | -5.25 cm/s |
Log Po/w (iLOGP) : | 2.56 |
Log Po/w (XLOGP3) : | 2.73 |
Log Po/w (WLOGP) : | 2.15 |
Log Po/w (MLOGP) : | 2.67 |
Log Po/w (SILICOS-IT) : | 2.8 |
Consensus Log Po/w : | 2.58 |
Lipinski : | 0.0 |
Ghose : | None |
Veber : | 0.0 |
Egan : | 0.0 |
Muegge : | 2.0 |
Bioavailability Score : | 0.55 |
Log S (ESOL) : | -2.74 |
Solubility : | 0.267 mg/ml ; 0.00183 mol/l |
Class : | Soluble |
Log S (Ali) : | -2.58 |
Solubility : | 0.386 mg/ml ; 0.00264 mol/l |
Class : | Soluble |
Log S (SILICOS-IT) : | -2.99 |
Solubility : | 0.15 mg/ml ; 0.00102 mol/l |
Class : | Soluble |
PAINS : | 0.0 alert |
Brenk : | 1.0 alert |
Leadlikeness : | 1.0 |
Synthetic accessibility : | 1.5 |
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
EXAMPLE 15 Preparation of 1-(4-ethoxyphenyl)-4-(trans-4-propylcyclohexyl)-3E-buten-1-yne (a compound of the formula (I) wherein A=1,4-phenylene, C=trans-1,4-cyclohexylene, n=0, m=1, l=0, R=propyl, X=H, Y=ethoxy and Z=H) The captioned compound (0.4 g) was obtained from 1-(4-ethoxyphenyl)-4-(4-propylcyclohexyl)-1-butyn-3-ol (2.5 g), prepared from <strong>[79887-14-2]4-ethoxyphenylacetylene</strong> (1.5 g) and 2-(4-propylcyclohexyl)acetaldehyde (1.7 g) in the same manner as in Example 1. CN 79.8-80.3 C. NI 135.8-136.1 C. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
EXAMPLE 16 Preparation of 1-(4-ethoxyphenyl)-4-(trans-4-pentylcyclohexyl)-3E-buten-1-yne (a compound of the formula (I) wherein A=1,4-phenylene, C=trans-1,4-cyclohexylene, n=0, m=1, l=0, R=pentyl, X=H, Y=ethoxy and Z=H) The captioned compound (0.4 g) was obtained from 1-(4-ethoxyphenyl)-4-(4-pentylcyclohexyl)-1-butyn-3-ol (3.1 g), prepared from <strong>[79887-14-2]4-ethoxyphenylacetylene</strong> (1.5 g) and 2-(4-pentylcyclohexyl)acetaldehyde (2.0 g), in the same manner as in Example 1. CN 68.9-70.0 C. NI 126.9-128.8 C. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
EXAMPLE 24 Preparation of 1-(4-ethoxyphenyl)-4-(trans-4-(trans-4-pentylcyclohexyl)cyclohexyl)-3E-buten-1-yne (a compound of the formula (I) wherein A=1,4-phenylene, C=trans-1,4-cyclohexylene, D=trans-1,4-cyclohexylene, n=0, m=1, l=1, R=pentyl, X=H, Y=ethoxy and Z=H) The captioned compound (0.5 g) was obtained from 1-(4-ethoxyphenyl)-4-(4-(4-pentylcyclohexyl)cyclohexyl)-1-butyn-3-ol (2.9 g), prepared from <strong>[79887-14-2]4-ethoxyphenylacetylene</strong> (1.5 g) and 2-(4-(4-pentylcyclohexyl)cyclohexyl)acetaldehyde (cis: trans=1:7) (2.9 g) in the same manner as in Example 1. NI 264.3-266.2 C. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 60℃;Inert atmosphere; | To a round bottom flask capped with septa was added <strong>[79887-14-2]1-ethoxy-4-ethynylbenzene</strong> (1.1 eq), 3,5-dichloropicolinonitrile (1 eq.), triethylamine (5 eq.), and anhydrous DMF (0.2 M). Vacuumed and nitrogen flushed for three times. CuI (0.05 eq.) and bis(triphenylphosphine)dichloro-palladium(II) (0.05 eq) were added. The septum was replaced with a refluxing condenser and the flask was heated at 60 C. overnight under nitrogen atmosphere. Upon completion of the reaction as monitored by TLC, the content of the flask was loaded onto a large silica gel column pretreated with hexanes. Flash chromatography (silica gel, hexanes:EtOAc (1:4%)) afforded the product 3-chloro-5-((4-ethoxyphenyl)ethynyl)picolinonitrile. | |
With triethylamine;bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In N,N-dimethyl-formamide; at 60℃;Inert atmosphere; | To a round bottom flask capped with septa was added l-ethoxy-4-ethynylbenzene (1 1 eq), 3,5-dichloropicolinonitrile (1 eq.), tnethylamine (5 eq.), and anhydrous DMF (0.2 M). Vacuumed and nitrogen flushed for three times. CuI (0.05 eq.) and bis(triphenylphosphine)dichloro-palladium(II) (0.05 eq) were added. The septum was replaced with a refluxing condenser and the flask was heated at 60 0C overnight under nitrogen atmosphere. Upon completion of the reaction as monitored by TLC, the content of the flask was loaded onto a large silica gel column pretreated with hexanes. Flash chromatography (silica gel, hexanes:EtOAc (1:4%)) afforded the product 3-chloro-5-((4-ethoxyphenyl)ethynyl)picolinonitrile. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
51% | With copper(l) iodide; triethylamine;bis-triphenylphosphine-palladium(II) chloride; at 20℃; for 0.25h; | Reference Example 47 methyl 4-[(4-ethoxyphenyl)ethynyl]-2-(methoxymethoxy)benzoate To a solution of methyl 2-hydroxy-4-iodobenzoate (1.00 g, 3.60 mmol) and <strong>[79887-14-2]1-ethoxy-4-ethynylbenzene</strong> (789 mg, 5.40 mmol) and copper(I) iodide (68.6 mg, 0.360 mmol) in triethylamine (9 mL) was added bis(triphenylphosphine)palladium(II) chloride (253 mg, 0.360 mmol), and the mixture was stirred under an argon stream at room temperature for 15 min. The reaction mixture was diluted with ethyl acetate, and the mixture was washed with water, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was dissolved in DMF (10 mL). Potassium carbonate (2.59 g, 18.8 mmol) and chloromethyl methyl ether (1.07 mL, 14.0 mmol) were added thereto, and the mixture was stirred at room temperature for 20 min. Water was added to the reaction mixture, and the mixture was extracted with ethyl acetate. The extract was washed twice with saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=9:1 to 1:1) to give the title compound (623 mg, yield 51%) as a yellow solid. 1H NMR (CDCl3) delta 1.43 (t, J=7.0 Hz, 3H), 3.54 (s, 3H), 3.89 (s, 3H), 4.05 (q, J = 7.0 Hz, 2H), 5.28 (s, 2H), 6.87 (d, J = 8.9 Hz, 2H), 7.17 (dd, J = 8.0, 1.4 Hz, 1H), 7.33 (d, J = 1.4 Hz, 1H), 7.47 (d, J = 8.9 Hz, 2H), 7.76 (d, J = 8.0 Hz, 1H). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With copper(l) iodide; diisopropylamine;dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In tetrahydrofuran; at 20℃; for 3h;Inert atmosphere; | To 1 .60 g (1 1 .0 mmol) <strong>[79887-14-2]4-ethoxyphenylacetylene</strong> in 40 mL THF are added 3.10 g (1 1 .0 mmol) 1 -bromo-4-iodo-benzene under argon, followed by 0.18 g (0.22 mmol) Pd(dppf)CI2 CH2CI2 as catalyst, 0.04 g (0.22 mmol) copper(l)iodide and 3.10 mL (21 .9 mmol) diisopropylamine as base. The mixture is stirred at rt for 3 h. After that time, EtOAc is added and the organic layer is washed with ammonia (5%, 2x) and water (1x). The organic layer is separated, dried over magnesium sulphate and the solvent is evaporated. The residue is purified by column chromatography (silicia gel;PE:EtOAc 9: 1 ) to yield the desired product.Ci6Hi3BrO (M = 301 .2 g/mol)ESI-MS: 309 [M+H]+ Rt (HPLC): 3.99 min (method I) | |
With diisopropylamine;copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; In tetrahydrofuran; at 20℃; for 3h;Inert atmosphere; | Example XIExample XI.11-Bromo-4-[(4-ethoxyphenyl)ethynyl]benzeneTo 1.60 g (11.0 mmol) <strong>[79887-14-2]4-ethoxyphenylacetylene</strong> in 40 mL THF are added 3.10 g (11.0 mmol) 1-bromo-4-iodo-benzene under argon, followed by 0.18 g (0.22 mmol) Pd(dppf)Cl2CH2Cl2 as catalyst, 0.04 g (0.22 mmol) copper(I)iodide and 3.10 mL (21.9 mmol) diisopropylamine as base. The mixture is stirred at rt for 3 h. After that time, EtOAc is added and the organic layer is washed with ammonia (5%, 2×) and water (1×). The organic layer is separated, dried over magnesium sulphate and the solvent is evaporated. The residue is purified by column chromatography (silicia gel; PE:EtOAc 9:1) to yield the desired product.C16H13BrO (M=301.2 g/mol)ESI-MS: 309 [M+H]+Rt (HPLC): 3.99 min (method I) |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With N-ethyl-N,N-diisopropylamine;bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; at 80℃; for 0.166667h;microwave irradiation; | Example 26; N-{2-[5-(4-Ethoxy-phenylethynyl)-pyridin-2-yl]-ethyl}-acetamide; 0.55 mL (3.91 mmol) DIPEA is added to 190 mg (0.78 mmol) N-[2-(5-bromo-pyridin-2-yl)-ethyl]-acetamide (I48.1), 3.72 mg (0.02 mmol) CuI and 13.7 mg (0.02 mmol) bis(triphenylphosphin)palladium-(II)-chloride. 171 mg (1.17 mmol) <strong>[79887-14-2]4-ethoxyphenylacetylene</strong> are added and the reaction mixture is heated for 10 min at 80 C. in a microwave oven. The mixture is diluted with EtOAc and washed with water (1×) and diluted aq. ammonia solution. The organic layer is dried with MgSO4 and the solvent is removed in vacuo. The residue is purified by HPLC (MeOH/H2O/NH3).C19H20N2O2 (M=308.4 g/mol)ESI-MS: 309 [M+H]+ Rt (HPLC): 1.97 (E) |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With SEC-BUTYLAMINE;bis-triphenylphosphine-palladium(II) chloride; In water; at 20 - 30℃; | Example 16; Example 16.1; General Route; N-(4-((4-Ethoxyphenyl)ethynyl)phenethyl)propionamide; 150 mg (1.03 mmol) <strong>[79887-14-2]1-ethoxy-4-ethynylbenzene</strong>, 327 mg (1.08 mmol) N-(4-iodophen-ethyl)propionamide (I47.2) and 36 mg (0.05 mmol) bis(triphenylphosphine)dichloro-palladium in 2.0 mL water and 1.5 mL sec-butylamine are stirred at r.t. over night and for additional 4 h at 30 C. The reaction mixture is partitioned between DCM and water. The solvent of the organic layer is evaporated in vacuo and the residue is purified by HPLC (MeOH/H2O/NH3).C21H23NO2 (M=321.4 g/mol)ESI-MS: 322 [M+H]+ Rt (HPLC): 2.16 min (method E) |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
91.55% | With copper(l) iodide; triphenylphosphine; In water; at 120℃; for 24h;Inert atmosphere; | General procedure: (0.05mmol, 9.5mg), PPh3 (0.1mmol, 26.2mg), and H2O (2.4g) were added to a 10ml round-bottomed flask. The mixture was stirred for 10min at room temperature. Compounds 4F (1mmol, 344.9mg) or 2F (1mmol, 302.9mg)and phenyl acetylene (1.2mmol) were added to this solution. The resulting mixture was stirred in oil bath, heated to 120C under nitrogen for 24h. The crude product was added to 50mL dichloromethane and then washed with water (3×30mL), and dried over anhydrous sodium sulfate. The solvent was removed under vacuum, and the residue was purified by chromatography on silica gel to give the target product |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
90.13% | With copper(l) iodide; triphenylphosphine; In water; at 120℃; for 24h;Inert atmosphere; | General procedure: (0.05mmol, 9.5mg), PPh3 (0.1mmol, 26.2mg), and H2O (2.4g) were added to a 10ml round-bottomed flask. The mixture was stirred for 10min at room temperature. Compounds 4F (1mmol, 344.9mg) or 2F (1mmol, 302.9mg)and phenyl acetylene (1.2mmol) were added to this solution. The resulting mixture was stirred in oil bath, heated to 120C under nitrogen for 24h. The crude product was added to 50mL dichloromethane and then washed with water (3×30mL), and dried over anhydrous sodium sulfate. The solvent was removed under vacuum, and the residue was purified by chromatography on silica gel to give the target product |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
89% | With copper(l) iodide; tetrabutylammonium acetate; potassium carbonate; triphenylphosphine; In water; dimethyl sulfoxide; at 100℃; for 24h;Inert atmosphere; Green chemistry; | General procedure: Vinyl halide (0.3mmol, if it is solid), CuI (0.0001 mol%, 20 muL in DMSO), PPh3 (2mol%), K2CO3 (0.6mmol), and tetra n-butylammonium acetate were added to a screw-capped test tube with 3 mL of deoxygenated water. The tube was evacuated and backfilled with argon (3 cycles). Under the argon atmosphere, the alkyne (0.4 mmol) and vinyl halide (if it is liquid) were added by syringe at room temperature. The mixture was heated to 100C and stirred for 24 h. After cooling to room temperature, the mixture was extracted three times with ethyl acetate. The organic layers were combined, dried over Na2SO4, and concentrated to yield the crude product, which was further purified by silica gel chromatography, using petroleum ether and ethyl acetate as eluent to provide the desired product. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
89% | With sodium azide; choline chloride; copper(l) chloride; In water; at 20℃; for 5h; | General procedure: A mixture of sodium azide (72 mg, 1.0 mmol), benzylbromide(171 mg, 1.0 mmol), phenylacetylene (102 mg, 1.0mmol), ChCl-CuCl derived from ChCl (3.5 mg, 0.025 mmol)and CuCl (4.9 mg, 0.025 mmol), and water (1mL) wasstirred at room temperature in a test tube. The reaction mixturewas stirred at room temperature for the lengths of timeshown in Table 2. Progress of the reaction was monitored byTLC. The reaction was extracted with CH2Cl2 (10 mL). Thecombined organic extracts were washed with water (5 mL)and dried using anhydrous MgSO4. The solvent was removedin vacuous and the crude product purified by flash chromatographyon silica gel (eluent: ethyl acetate/petroleum ether,1:10) to afford a white solid 3a (0.204 g, 87%). |
Tags: 79887-14-2 synthesis path| 79887-14-2 SDS| 79887-14-2 COA| 79887-14-2 purity| 79887-14-2 application| 79887-14-2 NMR| 79887-14-2 COA| 79887-14-2 structure
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :