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Chemical Structure| 81744-01-6 Chemical Structure| 81744-01-6

Structure of 81744-01-6

Chemical Structure| 81744-01-6

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Product Details of [ 81744-01-6 ]

CAS No. :81744-01-6
Formula : C13H9NO2Se
M.W : 290.18
SMILES Code : O=C1C2=CC=CC=C2[Se]N1C3=CC=C(O)C=C3

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Application In Synthesis of [ 81744-01-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 81744-01-6 ]

[ 81744-01-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 207399-07-3 ]
  • [ 81744-01-6 ]
  • C49H52N3O2Se(1+)*I(1-) [ No CAS ]
YieldReaction ConditionsOperation in experiment
92% (1) Take a 100ml three-necked flask, put magnets,Accurately weigh 0.5 mmol of 2- (4'-hydroxyphenyl) -1,2-benzoisoselenazole-3 (2H) -one,0.75 mmol of potassium tert-butoxide,Add another 15 ml of dry THF,Filled with nitrogen to replace and protect,And stirred under a nitrogen atmosphere at 15 C for 30 minutes to obtain a solution I. (2) Weigh 0.3 mmol of commercially available near-infrared fluorescent probe <strong>[207399-07-3]IR-780</strong> raw material (a heptachlorocyanine dye substituted with a median chlorine),Take 7.5 ml of solvent THF to dissolve to obtain solution II;Add solution II slowly to solution I,Slowly warm up to 60 ,Under nitrogen atmosphere, hold for 5h, then cool down,The solvent THF was removed under reduced pressure,A green solid was obtained and purified by silica gel column chromatography. The elution conditions were: ethyl acetate / methanol = 6/1,Collect green bands with a specific shift value (Rf value) of 0.2,0.12 g of a dark green solid was obtained with a yield of 92%.
 

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