[ CAS No. 81748-72-3 ]

Name: 81748-72-3|5-(Aminomethyl)quinolin-8-ol|97%
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Quality Control of [ 81748-72-3 ]

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Product Details of [ 81748-72-3 ]

CAS No. :	81748-72-3	MDL No. :	MFCD06740638
Formula :	C₁₀H₁₀N₂O	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	N/A
M.W :	174.20 g/mol	Pubchem ID :	-
Synonyms :

Safety of [ 81748-72-3 ]

Signal Word:	Warning	Class:
Precautionary Statements:	P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501	UN#:
Hazard Statements:	H302-H312-H332	Packing Group:
GHS Pictogram:

Application In Synthesis of [ 81748-72-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 81748-72-3 ]

[ 81748-72-3 ] Synthesis Path-Downstream 1~30

1
<i>N</i>-(8-hydroxy-[5]quinolylmethyl)-benzamide [ No CAS ]
[ 81748-72-3 ]

Yield	Reaction Conditions	Operation in experiment
	With hydrogenchloride

Reference： [1]Monti; Verona [Gazzetta Chimica Italiana, 1932, vol. 62, p. 878,882]

Yield	Reaction Conditions	Operation in experiment
	8-Hydroxy-5-acetaminomethyl-chinolin, HCl, Hydrolyse (als Dihydrochlorid);

3
[ 148-24-3 ]
[ 81748-72-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: H₂SO₄ 2: concentrated aqueous HCl
	Multi-step reaction with 3 steps 1: hydrogenchloride / water / 12 h / 20 °C 2: N,N-dimethyl-formamide / 5 h / 150 °C 3: hydrogenchloride / water / 20 °C / Reflux

Reference： [1]Monti; Verona [Gazzetta Chimica Italiana, 1932, vol. 62, p. 878,882]
[2]Karatas, Erhan; Ucan, Halil Ismet [Journal of Heterocyclic Chemistry, 2017, vol. 54, # 1, p. 692 - 698]

4
[ 81748-72-3 ]
[ 777085-55-9 ]
C₂₀H₂₄N₄O₃S [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
66%	With HBTU; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide; N,N-dimethyl-formamide at 20℃;

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

5
[ 81748-72-3 ]
[ 1094606-91-3 ]
[ 1094606-82-2 ]

Yield	Reaction Conditions	Operation in experiment
49%	With HBTU; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide; N,N-dimethyl-formamide

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

6
[ 81748-72-3 ]
Fmoc-Glu(O-t-Bu)-NHS [ No CAS ]
C₃₄H₃₅N₃O₆ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

7
C₄₀H₃₆BN₈O₄^(1-)*Li⁽¹⁺⁾ [ No CAS ]
[ 81748-72-3 ]

Yield	Reaction Conditions	Operation in experiment
	With water In methanol

Reference： [1]Location in patent: body text Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

8
[ 10136-57-9 ]
[ 81748-72-3 ]

Yield	Reaction Conditions	Operation in experiment
70%	Stage #1: 5-(chloromethyl)quinolin-8-ol With hexamethylenetetramine In dimethyl sulfoxide at 20℃; Stage #2: With hydrogenchloride In water at 20℃; for 48h;
	Stage #1: 5-(chloromethyl)quinolin-8-ol With potassium phtalimide In N,N-dimethyl-formamide at 150℃; for 5h; Stage #2: With hydrogenchloride In water at 150℃; for 9h;
	Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 5 h / 150 °C 2: hydrogenchloride / water / 20 °C / Reflux

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]
[2]Location in patent: scheme or table Madonna, Sébastien; Béclin, Christophe; Laras, Younes; Moret, Vincent; Marcowycz, Aline; Lamoral-Theys, Delphine; Dubois, Jacques; Barthelemy-Requin, Magali; Lenglet, Gaëlle; Depauw, Sabine; Cresteil, Thierry; Aubert, Geneviève; Monnier, Valérie; Kiss, Robert; David-Cordonnier, Marie-Hélène; Kraus, Jean-Louis [European Journal of Medicinal Chemistry, 2010, vol. 45, # 2, p. 623 - 638]
[3]Karatas, Erhan; Ucan, Halil Ismet [Journal of Heterocyclic Chemistry, 2017, vol. 54, # 1, p. 692 - 698]

9
[ 81748-72-3 ]
[ 1078-61-1 ]
[ 1094606-80-0 ]

Yield	Reaction Conditions	Operation in experiment
41%	Stage #1: 5-(aminomethyl)-8-hydroxyquinoline; dihydrocaffeic acid With HBTU; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide; N,N-dimethyl-formamide Stage #2: With trifluoroacetic acid In dimethyl sulfoxide

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

10
[ 81748-72-3 ]
[ 28920-43-6 ]
(9H-fluoren-9-yl)methyl (8-hydroxyquinolin-5-yl)methylcarbamate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
64%	With sodium hydrogencarbonate In water; N,N-dimethyl-formamide

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

11
[ 81748-72-3 ]
[ 59-30-3 ]
C₂₉H₂₇N₉O₆ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
59%	With HBTU; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide; N,N-dimethyl-formamide

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

12
[ 81748-72-3 ]
[ 84889-09-8 ]
C₄₃H₃₈N₄O₅ [ No CAS ]

Reference： [1]Tetrahedron,2008,vol. 64,p. 10986 - 10995

13
[ 81748-72-3 ]
[ 760190-09-8 ]
[ 1094606-83-3 ]

Yield	Reaction Conditions	Operation in experiment
98.6 mg	With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide

Reference： [1]Location in patent: experimental part Li, Lihua; Xu, Bing [Tetrahedron, 2008, vol. 64, # 49, p. 10986 - 10995]

14
[ 10136-57-9 ]
[ 81748-72-3 ]
[ 1215290-53-1 ]

Yield	Reaction Conditions	Operation in experiment
73%	With potassium carbonate In acetonitrile at 50℃; for 24h;

Reference： [1]Location in patent: experimental part Madonna, Sébastien; Béclin, Christophe; Laras, Younes; Moret, Vincent; Marcowycz, Aline; Lamoral-Theys, Delphine; Dubois, Jacques; Barthelemy-Requin, Magali; Lenglet, Gaëlle; Depauw, Sabine; Cresteil, Thierry; Aubert, Geneviève; Monnier, Valérie; Kiss, Robert; David-Cordonnier, Marie-Hélène; Kraus, Jean-Louis [European Journal of Medicinal Chemistry, 2010, vol. 45, # 2, p. 623 - 638]

15
[ 81748-72-3 ]
[ 100-44-7 ]
[ 1215290-49-5 ]

Yield	Reaction Conditions	Operation in experiment
75%	With potassium carbonate In acetonitrile at 50℃; for 24h;

16
[ 81748-72-3 ]
[ 874-60-2 ]
[ 1215290-52-0 ]

Yield	Reaction Conditions	Operation in experiment
75%	With potassium carbonate In acetonitrile at 50℃; for 48h;

17
[ 81748-72-3 ]
[ 292638-85-8 ]
[ 1283093-93-5 ]

Yield	Reaction Conditions	Operation in experiment
	In methanol at 20℃; for 24h;

Reference： [1]Location in patent: experimental part Zhang, Qi; Sha, Yaowu; Wang, Jin-Hui [Molecules, 2010, vol. 15, # 5, p. 2962 - 2971]

18
2-((8-hydroxyquinolin-5-yl)methyl)isoindoline-1,3-dione [ No CAS ]
[ 81748-72-3 ]

Yield	Reaction Conditions	Operation in experiment
80%	With hydrogenchloride In water at 20℃; Reflux;
75%	With hydrogenchloride for 12h; Reflux;	5 Example 5 5-(Aminomethyl)quinoline-8-ol Add 2-(((8-hydroxyquinolin-5-yl)methyl)isoindolin-1,3-dione (780 mg, 2.56 mmol) to concentrated hydrochloric acid (50 mL). Heat to reflux After 12 hours, the solution changed from turbid to clear, and the reaction was completed.After cooling to room temperature, the solid obtained after vacuum drying was dissolved in water, sodium bicarbonate solution was added to adjust the pH to neutral, and then suction filtered to obtain 334.47 mg of brown solid with a yield of 75%.

Reference： [1]Karatas, Erhan; Ucan, Halil Ismet [Journal of Heterocyclic Chemistry, 2017, vol. 54, # 1, p. 692 - 698]
[2]Current Patent Assignee: SUN YAT-SEN UNIVERSITY (CHINA) - CN111689944, 2020, A Location in patent: Paragraph 0093-0096

19
[ 81748-72-3 ]
[ 3140-75-8 ]
C₅₄H₃₉N₉O₆ [ No CAS ]

Reference： [1]Journal of Heterocyclic Chemistry,2017,vol. 54,p. 692 - 698

20
[ 81748-72-3 ]
[ 951-82-6 ]
C₂₁H₂₂N₂O₅ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethyl cyanoglyoxylate-2-oxime In water; N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;	General procedure for synthesis of 5a-5f General procedure: To a stirred solution of compound 4 (1.0mmol, 140mg) or 5-amino-8-hydroxyquinoline dihydrochloride and carboxylic acid (1.2mmol) in DMF-H2O (1:5) were added oxyma (2.0mmol, 284mg), EDCI (2.0mmol, 310mg), and NaHCO3 (6.0mmol, 636mg). After stirring at room temperature for 12h, the solution was extracted with EtOAc. The combined organic layers were washed with brine (3mL), and then dried over Na2SO4. Concentration of organic phase gave crude product which was directly used for next step without purification.

21
[ 81748-72-3 ]
[ 104-03-0 ]
C₁₈H₁₅N₃O₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethyl cyanoglyoxylate-2-oxime In water; N,N-dimethyl-formamide Inert atmosphere;	General procedure for synthesis of 5a-5f General procedure: To a stirred solution of compound 4 (1.0mmol, 140mg) or 5-amino-8-hydroxyquinoline dihydrochloride and carboxylic acid (1.2mmol) in DMF-H2O (1:5) were added oxyma (2.0mmol, 284mg), EDCI (2.0mmol, 310mg), and NaHCO3 (6.0mmol, 636mg). After stirring at room temperature for 12h, the solution was extracted with EtOAc. The combined organic layers were washed with brine (3mL), and then dried over Na2SO4. Concentration of organic phase gave crude product which was directly used for next step without purification.

22
[ 81748-72-3 ]
[ 405-50-5 ]
C₁₈H₁₅FN₂O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethyl cyanoglyoxylate-2-oxime In water; N,N-dimethyl-formamide Inert atmosphere;	General procedure for synthesis of 5a-5f General procedure: To a stirred solution of compound 4 (1.0mmol, 140mg) or 5-amino-8-hydroxyquinoline dihydrochloride and carboxylic acid (1.2mmol) in DMF-H2O (1:5) were added oxyma (2.0mmol, 284mg), EDCI (2.0mmol, 310mg), and NaHCO3 (6.0mmol, 636mg). After stirring at room temperature for 12h, the solution was extracted with EtOAc. The combined organic layers were washed with brine (3mL), and then dried over Na2SO4. Concentration of organic phase gave crude product which was directly used for next step without purification.

23
[ 81748-72-3 ]
[ 32857-62-8 ]
C₁₉H₁₅F₃N₂O₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethyl cyanoglyoxylate-2-oxime In water; N,N-dimethyl-formamide Inert atmosphere;	General procedure for synthesis of 5a-5f General procedure: To a stirred solution of compound 4 (1.0mmol, 140mg) or 5-amino-8-hydroxyquinoline dihydrochloride and carboxylic acid (1.2mmol) in DMF-H2O (1:5) were added oxyma (2.0mmol, 284mg), EDCI (2.0mmol, 310mg), and NaHCO3 (6.0mmol, 636mg). After stirring at room temperature for 12h, the solution was extracted with EtOAc. The combined organic layers were washed with brine (3mL), and then dried over Na2SO4. Concentration of organic phase gave crude product which was directly used for next step without purification.

24
[ 4053-45-6 ]
[ 81748-72-3 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: sodium azide / acetone / 20 h / Reflux; Inert atmosphere 2: palladium 10% on activated carbon; hydrogen / ethyl acetate / Reflux

25
[ 1005143-73-6 ]
[ 81748-72-3 ]

Yield	Reaction Conditions	Operation in experiment
68%	With palladium 10% on activated carbon; hydrogen In ethyl acetate Reflux;	38 Synthesis of 91 5-(aminomethyl)quinolin-8-ol (4) A suspension of azide 88 3 (2.00g, 10mol) and 10% 92 Pd/C (0.15g) in 93 ethylacetate (15mL) was hydrogenated overnight, the reaction mixture was filtered off and washed with dichloromethane-methanol (1:1). The combined filtration was evaporated under vacuum to give the oily crude which was purified with flash chromatography on silica. Compound 4 was eluted out with dichloromethane/94 methanol (15:0-10:1) (1.18g, 68%). 1H NMR (400MHz, DMSO-d6) δ 8.86 (dd, J=4.1, 1.6Hz, 1H), 8.57 (dd, J=8.6, 1.6Hz, 1H), 7.58 (dd, J=8.5, 4.1Hz, 1H), 7.44 (dd, J=7.8, 0.9Hz, 1H), 7.02 (d, J=7.8Hz, 1H), 4.10 (d, J=0.8Hz, 2H).
	With water; triphenylphosphine In tetrahydrofuran at 20℃; for 24h;

Reference： [1]Wang, Qinghui; Arnst, Kinsie E.; Xue, Yi; Lei, Zi-Ning; Ma, Dejian; Chen, Zhe-Sheng; Miller, Duane D.; Li, Wei [European Journal of Medicinal Chemistry, 2018, vol. 149, p. 211 - 224]
[2]El Faydy; Lakhrissi; Guenbour; Kaya; Bentiss; Warad; Zarrouk [Journal of Molecular Liquids, 2019, vol. 280, p. 341 - 359]

26
[ 81748-72-3 ]
N-((8-hydroxy-7-(pyrrolidin-1-ylmethyl)quinolin-5-yl)methyl)-2-(3,4,5-trimethoxyphenyl)acetamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydrogencarbonate; ethyl cyanoglyoxylate-2-oxime / N,N-dimethyl-formamide; water / 12 h / 20 °C / Inert atmosphere 2: ethanol / Reflux; Inert atmosphere

27
[ 81748-72-3 ]
N-((8-hydroxy-7-(pyrrolidin-1-ylmethyl)quinolin-5-yl)methyl)-2-(4-nitrophenyl)acetamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydrogencarbonate; ethyl cyanoglyoxylate-2-oxime / N,N-dimethyl-formamide; water / Inert atmosphere 2: ethanol / Reflux; Inert atmosphere

28
[ 81748-72-3 ]
2-(4-fluorophenyl)-N-((8-hydroxy-7-(pyrrolidin-1-ylmethyl)quinolin-5-yl)methyl)acetamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydrogencarbonate; ethyl cyanoglyoxylate-2-oxime / N,N-dimethyl-formamide; water / Inert atmosphere 2: ethanol / Reflux; Inert atmosphere

29
[ 81748-72-3 ]
1-(4-bromobenzyl)-3-((8-hydroxy-7-(pyrrolidin-1-ylmethyl)quinolin-5-yl)methyl)urea [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: trimethylamine / dichloromethane / 5 h / 20 °C / Inert atmosphere 2: ethanol / Reflux; Inert atmosphere

30
[ 81748-72-3 ]
1-bromo-4-(isocyanatomethyl)benzene [ No CAS ]
1-(4-bromobenzyl)-3-((8-hydroxyquinolin-5-yl)methyl)urea [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With trimethylamine In dichloromethane at 20℃; for 5h; Inert atmosphere;	39 Synthesis of 1-(4-bromobenzyl)-3-((8-hydroxyquinolin-5-yl)methyl)urea (7) To a stirred solution of compound 91 4 (1.0mmol, 140mg) and 96 4-bromobenzyl isocyanate (1.0mmol, 212mg) in anhydrous 97 dichloromethane (5mL) were added catalytic amount of 98 trimethylamine (0.1mmol, 10.1mg). After stirring at room temperature for 5h, solvent was removed under reduced pressure to give crude 99 product which was directly used for next step without purification.

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[ 81748-72-3 ]

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Ghs Precautionary Statements

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Code	Phrase
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P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 81748-72-3 ]

Quality Control of [ 81748-72-3 ]

Related Doc. of [ 81748-72-3 ]

Product Details of [ 81748-72-3 ]

Safety of [ 81748-72-3 ]

Application In Synthesis of [ 81748-72-3 ]

[ 81748-72-3 ] Synthesis Path-Downstream 1~30

Related Functional Groups of [ 81748-72-3 ]

Amines

Alcohols

Related Parent Nucleus of [ 81748-72-3 ]

Quinolines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 81748-72-3 ]

Related Parent Nucleus of
[ 81748-72-3 ]