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Chemical Structure| 820232-35-7 Chemical Structure| 820232-35-7

Structure of 820232-35-7

Chemical Structure| 820232-35-7

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Product Details of [ 820232-35-7 ]

CAS No. :820232-35-7
Formula : C6H16N2O6
M.W : 305.37
SMILES Code : O=C(C1CCC(NC(OCC2=CC=CC=C2)=O)CC1)OCC

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Application In Synthesis of [ 820232-35-7 ]

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  • Downstream synthetic route of [ 820232-35-7 ]

[ 820232-35-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 51498-33-0 ]
  • [ 501-53-1 ]
  • [ 820232-35-7 ]
YieldReaction ConditionsOperation in experiment
98.5% With sodium carbonate; In water; toluene; at 10℃; for 0.5h; To the residue of <strong>[51498-33-0]ethyl 4-aminocyclohexanecarboxylate</strong> (Net 33 g, 0.2 mol) obtained in (1) above is dissolved in toluene (165 mL) and water (165 mL), and thereto is added sodium carbonate (31.8 g, 0.3 mol). Benzyloxycarbonyl chloride (34.1 g, 0.2 mol) is added dropwise to the mixture at 10C or below over 30 minutes, and thereto is added water to dissolve the resulting salts, whereby the solution is partitioned. The aqueous layer is re-extracted with ethyl acetate. The organic layers are combined, dried over magnesium sulfate, and concentrated to give ethyl 4-benzyloxycarbonylaminocyclohexanecarboxylate (60.17 g, yield: 98.5%) as oil. IR : nu = 3346, 1710 cm-1 MS: m/z = 306 [(M+1)+] .
 

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