Home Cart Sign in  
Chemical Structure| 82414-44-6 Chemical Structure| 82414-44-6

Structure of 82414-44-6

Chemical Structure| 82414-44-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 82414-44-6 ]

CAS No. :82414-44-6
Formula : C6H6BrNO
M.W : 188.02
SMILES Code : OC1=CC=CN=C1CBr
MDL No. :MFCD00296919

Safety of [ 82414-44-6 ]

Application In Synthesis of [ 82414-44-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 82414-44-6 ]

[ 82414-44-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 14173-30-9 ]
  • [ 144-55-8 ]
  • [ 82414-44-6 ]
YieldReaction ConditionsOperation in experiment
With hydrogen bromide; acetic acid; In dichloromethane; water; Production Example 6-1: 2-Bromomethyl-3-hydroxypyridine To 25% acetic acid solution of hydrogen bromide (12.8g, 39.6mmol), was added <strong>[14173-30-9]3-hydroxy-2-hydroxymethylpyridine hydrochloride</strong> (5.0g, 54.7mmol). The mixture was reacted at 110C for 1 hour. Furthermore, was added 25% acetic acid solution of hydrogen bromide (4.90g, 15.1mmol) dropwise, and the mixture was reacted for 2 hours. After cooling, the reaction mixture was poured into 50mL of water, and the pH of the mixture was adjusted to 8 by adding saturated aqueous sodium hydrogencarbonate solution. After extraction with 50mL of dichloromethane for four times, the dichloromethane layers were concentrated. The crude product after the concentration was purified by silica gel column chromatography, thereby to yield 1.36g of the target compound. 1H-NMR (CDCl3, 300MHz): δ 5.31(2H, s, CH2Br), 7.20-7.32(2H, m, Py), 8.18-8.21(1H, m, Py), 8.55(1H, bs, OH)
 

Historical Records

Technical Information

Categories