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Chemical Structure| 828911-01-9 Chemical Structure| 828911-01-9

Structure of 828911-01-9

Chemical Structure| 828911-01-9

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Product Details of [ 828911-01-9 ]

CAS No. :828911-01-9
Formula : C13H19N3O
M.W : 233.31
SMILES Code : O=C(N)CN1CCN(CC2=CC=CC=C2)CC1
MDL No. :MFCD06050367

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Application In Synthesis of [ 828911-01-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 828911-01-9 ]

[ 828911-01-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 50-00-0 ]
  • [ 1544-75-8 ]
  • [ 828911-01-9 ]
  • N-benzyl-2-{4-[(5-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl]piperazin-1-yl}acetamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
72.1% In ethanol; at 20℃; for 15h; Obtained through a method the N- acetyl benzylamine piperazine (II) intermediate (19. 6mmol), an alcoholic solution of formaldehyde (16. 3mmol), 5- fluoro-1,3-dihydro-benzimidazol-2-one (16. 3mmol) into 30ml of absolute ethanol, at room temperature for 15h. The reaction was concentrated under reduced pressure to give a crude oil. The crude product was purified by silica gel column chromatography to obtain the free base of N- benzyl-2- {4 - [(5-fluoro-2-oxo-2,3-dihydro-benzo -111- [(1] imidazol-1 yl) methyl] piperazin-1-yl} acetamide (V_19), 4.67g, yield 72.1%.
  • 2
  • [ 1544-75-8 ]
  • [ 828911-01-9 ]
  • N-benzyl-2-{4-[(5-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl]piperazin-1-yl}acetamide hydrochloride [ No CAS ]
 

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