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Chemical Structure| 83461-40-9 Chemical Structure| 83461-40-9

Structure of 83461-40-9

Chemical Structure| 83461-40-9

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Product Details of [ 83461-40-9 ]

CAS No. :83461-40-9
Formula : C7H14O5S
M.W : 210.25
SMILES Code : CS(=O)(OC[C@@H]1OC(C)(C)OC1)=O

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Application In Synthesis of [ 83461-40-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 83461-40-9 ]

[ 83461-40-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6665-98-1 ]
  • [ 83461-40-9 ]
  • (S)-2-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)-6-nitrophenol [ No CAS ]
YieldReaction ConditionsOperation in experiment
To a solution of <strong>[6665-98-1]3-nitrobenzene-1,2-diol</strong> (5-la) (0.10 g, 0.65 mmol) in DMSO (1.5 mL) was added NaOH(52 g, 1.3 mmol) at 25C. The mixture was stirred at 25C for 15 mm. Then (R)-(2,2-dimethyl-1,3-dioxolan-4-yl)methyl methanesulfonate (5-lb) was added to the mixture at 25C and stirred at 80C for 12 h. The mixture was poured into ice water (20 mL) at 0C. The mixture was extracted by EtOAc, washed with brine (15 mL), dried over Na2SO4 and concentrated to give the crude product of (S)-2-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)- 6-nitrophenol (5-lc), which was used for next step directly.
 

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