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Chemical Structure| 83781-95-7 Chemical Structure| 83781-95-7

Structure of 83781-95-7

Chemical Structure| 83781-95-7

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Product Details of [ 83781-95-7 ]

CAS No. :83781-95-7
Formula : C8H8BrClO
M.W : 235.51
SMILES Code : COC1C=CC=C(Cl)C=1CBr
MDL No. :MFCD18393578
InChI Key :UBHMKGCZRSUSPG-UHFFFAOYSA-N
Pubchem ID :22327443

Safety of [ 83781-95-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P301+P330+P331-P302+P352-P304+P340-P305+P351+P338-P310
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 83781-95-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 83781-95-7 ]

[ 83781-95-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7746-27-2 ]
  • [ 83781-95-7 ]
  • 6-bromo-1-(2-chloro-6-methoxybenzyl)-3-methyl-1H-indazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
218 mg With potassium carbonate; In N,N-dimethyl-formamide; at 1 - 40℃; for 20h; (2) Synthesis of 6-bromo-1-(2-chloro-6-methoxybenzyl)-3-methyl-1H-indazole [28-2] (hereinafter referred to as a compound [28-2]) The titled compound (218 mg) as a yellow white 131 solid was prepared from <strong>[7746-27-2]6-bromo-3-methyl-1H-indazole</strong>, which was obtained by the method described in the document (JP 2009-528363 W) (164 mg), and the compound [28-1] (237 mg), according to the method of the process (1) in Example 1. 1H-NMR (400 MHz, CDCl3) delta: 7.65 (1H, t, J = 0.7 Hz), 7.44 (1H, d, J = 8.5 Hz), 7.22 (1H, t, J = 8.8 Hz), 7.17-7.15 (1H, m), 7.04 (1H, d, J = 8.1 Hz), 6.81 (1H, d, J = 8.3 Hz), 5.60 (2H, s), 3.81 (3H, s), 2.50 (3H, s).
 

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