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Chemical Structure| 84400-99-7 Chemical Structure| 84400-99-7

Structure of 84400-99-7

Chemical Structure| 84400-99-7

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Product Details of [ 84400-99-7 ]

CAS No. :84400-99-7
Formula : C7H4ClNO
M.W : 153.57
SMILES Code : ClC1=NC=CC2=C1OC=C2
MDL No. :MFCD09834947
InChI Key :YJUYPLVLAHBYCM-UHFFFAOYSA-N
Pubchem ID :12826107

Safety of [ 84400-99-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H320-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 84400-99-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 84400-99-7 ]

[ 84400-99-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 26956-43-4 ]
  • [ 84400-99-7 ]
YieldReaction ConditionsOperation in experiment
51% With trichlorophosphate; for 3h;Reflux; Phosphorous oxychloride (2.5 mL, 27.31 mmol) was added to <strong>[26956-43-4]furo[3,2-c]pyridin-4(5H)-one</strong> (Example 221 B, 0.249g, 1.1843 mmol) at 0 C and the resulting mixture was stirred at reflux for 3h. Ice was then added to the mixture and this was stirred for an additional hour at RT. The mixture was extracted with dichloromethane (3x) and the combined organic extracts were dried over anhydrous sodium sulfate, filtered and concentrated. The residue was purified by flash chromatography (Isco, ethyl acetate / dichloromethane) to give the title material (0.145g, 51%) as white crystals. LC (Method A): 1.451 min. 1H NMR (DMSO-d6) delta ppm: 8.30 (d, J=6.0 Hz, 1H), 8.26 (d, J=1.2 Hz, 1H), 7.78 (d, J=6.0 Hz, 1H), 7.13 (d, J=1.2 Hz, 1H).
 

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