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[ CAS No. 84547-84-2 ]

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Chemical Structure| 84547-84-2
Chemical Structure| 84547-84-2
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Product Details of [ 84547-84-2 ]

CAS No. :84547-84-2 MDL No. :MFCD00463982
Formula : C5H5BrN2O2 Boiling Point : 347.4°C at 760 mmHg
Linear Structure Formula :- InChI Key :-
M.W :205.01 g/mol Pubchem ID :673686
Synonyms :

Safety of [ 84547-84-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 84547-84-2 ]

  • Upstream synthesis route of [ 84547-84-2 ]
  • Downstream synthetic route of [ 84547-84-2 ]

[ 84547-84-2 ] Synthesis Path-Upstream   1~6

  • 1
  • [ 15803-02-8 ]
  • [ 124-38-9 ]
  • [ 84547-84-2 ]
YieldReaction ConditionsOperation in experiment
77.3 g With n-butyllithium; diisopropylamine In tetrahydrofuran; acetone at -78 - 0℃; for 1 h; Inert atmosphere tHF (anhydrous) 600 ml was added to a 2 L reaction flask.Diisopropylamine 65.4g,Argon replacement protection,Dry ice acetone was cooled to -78 °C. Add 2.5M n-butyl lithium 258ml,The temperature is raised at 0 ° C for 0.5 h, and the temperature is lowered to -78 ° C.80.0 g of 1-methyl-4-bromopyrazole was added dropwise, and the reaction was maintained at -78 ° C for 1 h.Pass dry carbon dioxide gas until the reaction is complete.TLC showed the reaction was complete, and 1N HCl was added dropwise to adjust pH = 2-3.A large amount of white solid precipitated. After cooling at 0 ° C for 3 h, filter.Drying at 40 ° C for 16 h gave a white solid compound 22 (77.3 g).
Reference: [1] Patent: CN108264520, 2018, A, . Location in patent: Paragraph 0261; 0262; 0263; 0264; 0265
  • 2
  • [ 5775-86-0 ]
  • [ 84547-84-2 ]
Reference: [1] J. Gen. Chem. USSR (Engl. Transl.), 1982, vol. 52, # 11, p. 2291 - 2296[2] Zhurnal Obshchei Khimii, 1982, vol. 52, # 11, p. 2592 - 2598
  • 3
  • [ 16034-46-1 ]
  • [ 84547-84-2 ]
Reference: [1] J. Gen. Chem. USSR (Engl. Transl.), 1982, vol. 52, # 11, p. 2291 - 2296[2] Zhurnal Obshchei Khimii, 1982, vol. 52, # 11, p. 2592 - 2598
  • 4
  • [ 13808-64-5 ]
  • [ 84547-84-2 ]
Reference: [1] Patent: WO2005/66147, 2005, A1, . Location in patent: Page/Page column 183
  • 5
  • [ 694-31-5 ]
  • [ 84547-84-2 ]
Reference: [1] J. Gen. Chem. USSR (Engl. Transl.), 1982, vol. 52, # 11, p. 2291 - 2296[2] Zhurnal Obshchei Khimii, 1982, vol. 52, # 11, p. 2592 - 2598
  • 6
  • [ 15803-02-8 ]
  • [ 591-51-5 ]
  • [ 84547-84-2 ]
Reference: [1] Justus Liebigs Annalen der Chemie, 1959, vol. 625, p. 55,60
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