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Chemical Structure| 851607-30-2 Chemical Structure| 851607-30-2

Structure of 851607-30-2

Chemical Structure| 851607-30-2

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Product Details of [ 851607-30-2 ]

CAS No. :851607-30-2
Formula : C7H7BrClNO
M.W : 236.49
SMILES Code : CC1=C(Br)C(OC)=NC=C1Cl
MDL No. :MFCD17014980

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Application In Synthesis of [ 851607-30-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 851607-30-2 ]

[ 851607-30-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 133627-45-9 ]
  • [ 851607-30-2 ]
  • 2
  • [ 717843-51-1 ]
  • [ 851607-30-2 ]
YieldReaction ConditionsOperation in experiment
100 mg With N-chloro-succinimide; In N,N-dimethyl-formamide; at 80.0℃; for 3.0h; (3) Synthesis of 3-bromo-5-chloro-2-methoxy-4-methylpyridine <strong>[717843-51-1]3-bromo-2-methoxy-4-methylpyridine</strong> (100 mg) was added to DMF (575 muL). NCS (72.5 mg) was added to the solution, and the mixture was stirred at 80 C. for three hours. The reaction mixture was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (ethyl acetate/n-heptane, 5% to 30%) to give the title compound (100 mg). 1H-NMR (400 MHz, CDCl3) delta (ppm): 2.51 (s, 3H), 3.98 (s, 3H), 8.02 (s, 1H).
 

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