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Chemical Structure| 85196-50-5 Chemical Structure| 85196-50-5

Structure of 85196-50-5

Chemical Structure| 85196-50-5

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Product Details of [ 85196-50-5 ]

CAS No. :85196-50-5
Formula : C8H10Cl2N4
M.W : 233.10
SMILES Code : ClC1=NC(NC2CCCC2)=NC(Cl)=N1

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Application In Synthesis of [ 85196-50-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 85196-50-5 ]

[ 85196-50-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 85196-50-5 ]
  • [ 52023-68-4 ]
  • [ 733039-00-4 ]
YieldReaction ConditionsOperation in experiment
In chloroform; at -10 - 20℃; for 21h; To a stirring solution OF CYCLOPENTYL- (4, 6-DICHLORO- [1, 3,5] triazin-2-yl) - amine (Compound A') (0.105g, 0. 451MMOL) in chloroform (5 mL) at-10 C was added a solution of <strong>[52023-68-4]6-morpholin-4-yl-pyridin-3-ylamine</strong> (0. 081g, 0.451 mmol) in chloroform (3 mL) over 20 minutes. The reaction was allowed to stir at-10 C for 1 hour. The reaction was allowed to warm to ambient temperature and stirred overnight. After stirring for 20 hours, the reaction mixture was diluted with dichloromethane and partitioned with water. The organic phase was washed twice with water and then collected, dried over NASSO., filtered and concentrated under reduced pressure to yield 6-CHLORO-N-CYCLOPENTYL-N'-(6-MORPHOLIN-4-YL-PYRIDIN-3- YL)- [1, 3,5] triazine-2, 4-diamine (Compound E) as a purple foam (0. 103G, 33%). MS 376.1 ; MP 218-219.
 

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