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Chemical Structure| 856452-73-8 Chemical Structure| 856452-73-8

Structure of 856452-73-8

Chemical Structure| 856452-73-8

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Product Details of [ 856452-73-8 ]

CAS No. :856452-73-8
Formula : C8H5ClN4O2
M.W : 224.60
SMILES Code : O=[N+](C1=CC=C(N2N=CN=C2)C(Cl)=C1)[O-]
MDL No. :MFCD18622135

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Application In Synthesis of [ 856452-73-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 856452-73-8 ]

[ 856452-73-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 288-88-0 ]
  • [ 2106-50-5 ]
  • [ 856452-73-8 ]
YieldReaction ConditionsOperation in experiment
49A: 1-(2-Chloro-4-nitro-phenyl)-1H-[1,2,4]triazole 1.7 g of 1,2,4 triazole was dissolved in 70 ml of DMF and 1 g of NaH (60% in oil)was added. The mixture was stirred for 30 mn at RT and 1 equivalent <strong>[2106-50-5]2-chloro-4-fluoro-nitrobenzene</strong> was added. The reaction mixture was stirred at RT for 1 day and water was added. The reaction mixture was extracted with dichloromethane, the dichloromethane phase was washed three times with water and evaporated. The residue was triturated in isopropyl ether to give 1.5 g of a yellow powder used as such in the next step. 1H NMR (DMSO-d6): 9.15 (1H,s), 8.62 (1H,d), 8.46(1H,m), 8.35(1H, s), 7.95 (1H,d)
 

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