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[ CAS No. 857784-97-5 ] {[proInfo.proName]}

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Chemical Structure| 857784-97-5
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Product Details of [ 857784-97-5 ]

CAS No. :857784-97-5 MDL No. :MFCD26516270
Formula : C12H7IO Boiling Point : -
Linear Structure Formula :- InChI Key :UPOAJQCHRDVQEZ-UHFFFAOYSA-N
M.W : 294.09 Pubchem ID :11680890
Synonyms :

Safety of [ 857784-97-5 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338 UN#:
Hazard Statements:H302-H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 857784-97-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 857784-97-5 ]

[ 857784-97-5 ] Synthesis Path-Downstream   1~32

  • 1
  • dibenzo[b,d]furan-1-yl-boronic acid [ No CAS ]
  • [ 857784-97-5 ]
YieldReaction ConditionsOperation in experiment
88% With iodine; potassium carbonate In acetonitrile at 80℃; for 9h; Inert atmosphere; Schlenk technique; Sealed tube; General procedure: Arylboronic acid 1 (0.5 mmol) and K2CO3 (1 mmol, 138.0mg) were added to a 20 mL Schlenk-tube equipped with amagnetic stir bar. The tube was evacuated twice and backfilledwith N2. MeCN (2 mL) and I2 (0.75 mmol, 191 mg)were added to the tube at r.t. under a stream of N2, and thetube was sealed and placed into a pre-heated oil bath at 80 °Cfor 8-12 h. The resulting solution was cooled to r.t. and H2O(10 mL) was added. The aq layer was extracted with EtOAc (3 × 5 mL). For products 2s and 2t, HCl (1 M) was added tothe aq solution until pH 2 before extraction. The combinedorganic phase was dried over anhydrous Na2SO4, filteredand concentrated by rotary evaporation. Purification of theresidue by column chromatography on silica gel providedthe desired product 2a-v
  • 2
  • [ 1592-95-6 ]
  • [ 857784-97-5 ]
  • C24H14BrNO [ No CAS ]
YieldReaction ConditionsOperation in experiment
74% With tris-(dibenzylideneacetone)dipalladium(0); triphenylphosphine; sodium t-butanolate In toluene at 100℃; I.4 (4) synthesis of Sub 1 (8) in round bottom flask 3-bromo-9H-carbazole (4.9g, 20mmol), 1-iododibenzo[b, d]furan (5.9g, 20mmol), Pd 2 (dba) 3 (0.9g, 1mmol), PPh 3 (0.5g, 2mmol), NaO t-Bu (5.8g, 60mmol), toluene (210 ml) added of after where the progress of the reaction to 100 °C in. When reaction is completed after ether and a water extraction of organic layer MgSO 4 to dry a silicagel column are formed after the products and recrystallization 6.1g (yield: 74%)is obtained.
  • 3
  • [ 857784-97-5 ]
  • C14H8O [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0); triethylamine; copper(l) iodide / tetrahydrofuran / 16 h / 80 °C / Inert atmosphere; Sealed tube 2: potassium carbonate; methanol / tetrahydrofuran / 2 h / 25 °C / Inert atmosphere
  • 4
  • [ 857784-97-5 ]
  • 1-(6,11-dibromo-1,4-diphenyltriphenylen-2-yl)dibenzofuran [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: tetrakis(triphenylphosphine) palladium(0); triethylamine; copper(l) iodide / tetrahydrofuran / 16 h / 80 °C / Inert atmosphere; Sealed tube 2: potassium carbonate; methanol / tetrahydrofuran / 2 h / 25 °C / Inert atmosphere 3: o-xylene / 16 h / 145 °C / Inert atmosphere; Schlenk technique
  • 5
  • [ 857784-97-5 ]
  • [ 1066-54-2 ]
  • (dibenzofuran-1-ylethynyl)trimethylsilane [ No CAS ]
YieldReaction ConditionsOperation in experiment
79% With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine In tetrahydrofuran at 80℃; for 16h; Inert atmosphere; Sealed tube;
  • 6
  • [ 857784-97-5 ]
  • C60H39N5O [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; tetrahydrofuran / 6 h / Inert atmosphere; Reflux 2.1: magnesium; iodine / tetrahydrofuran / 2 h / 80 °C 2.2: 20 °C 3.1: sodium t-butanolate; bis(tri-t-butylphosphine)palladium(0) / 5,5-dimethyl-1,3-cyclohexadiene / 4 h / Reflux
  • 7
  • [ 857784-97-5 ]
  • [ 89598-96-9 ]
  • 1-(3-bromophenyl)dibenzofuran [ No CAS ]
YieldReaction ConditionsOperation in experiment
81% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 6h; Inert atmosphere; Reflux; 3.2 Step 2) Preparation of compound 3-2 1-iododibenzo [b, d] furan (30 g, 102 mmol) and(3-bromophenyl) boronic acid (21.5 g, 107 mmol) was added to a solution ofWas dispersed in 250 mL of tetrahydrofuran,Potassium carbonate (28.2 g, 204 mmol) was added to a solution ofDissolved in 80 mL of water and added to the mixture.After nitrogen charging, tetrakis (triphenylphosphine) palladium (1.18 g, 1 mol%) was added to the suspension. Under nitrogen,The mixture was refluxed and stirred for 6 hours. When the reaction was completed, the reaction mixture was cooled to room temperature, the water layer was separated, and the organic layer was concentrated under reduced pressure.Ethanol and ethyl acetate were added to the concentrated compound and slurry was prepared to give Compound 3-2 (26.7 g, yield 81%).
  • 8
  • [ 50548-40-8 ]
  • [ 857784-97-5 ]
YieldReaction ConditionsOperation in experiment
44% Stage #1: 1-aminodibenzofuran With hydrogenchloride; sodium nitrite at -10 - -5℃; for 0.5h; Stage #2: With potassium iodide at 0 - 25℃; for 8h; 1.S3; 2.S3 The product 1-aminodibenzofuran obtained in the step S2 was placed in a 100 mL round bottom flask.Then add 29.9mL of 4mol/L hydrochloric acid to make the system strong acid, and cool down to -10 °C.Add sodium nitrite solution (2.26g, 0.033mol), and control the temperature to -5 °C.After stirring for 30 min, add KI solution (9 g, 0.055 mol), and control temperature is less than 0 °C.Then, the reaction was carried out at 25 ° C for 8 h, and after completion of the reaction, the solid was filtered, and the solid was dissolved with dimethyl ether (40 mL), and the insoluble solid was filtered, and the organic phase of the filtrate was washed twice with aqueous sodium thiosulfate solution.Wash once, concentrate the organic phase to 10 mL, add petroleum ether (4 mL) and filterGet the crude,Add petroleum ether (4mL) to the crude product to dissolve and crystallize.White solid product1-iododibenzofuran4.0g,The yield of the product was 44%.The purity is 99%.
  • 9
  • [ 99-65-0 ]
  • [ 857784-97-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: potassium <i>tert</i>-butylate; copper(l) iodide; pyridine / Dimethyl ether / 1 h / Inert atmosphere; Large scale 1.2: 7 h / 10 - 100 °C / Inert atmosphere; Large scale 2.1: iron; ammonium chloride / ethanol; water / 3 h / 50 °C 3.1: hydrogenchloride; sodium nitrite / 0.5 h / -10 - -5 °C 3.2: 8 h / 0 - 25 °C
  • 10
  • [ 533-58-4 ]
  • [ 857784-97-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: potassium <i>tert</i>-butylate; copper(l) iodide; pyridine / Dimethyl ether / 1 h / Inert atmosphere; Large scale 1.2: 7 h / 10 - 100 °C / Inert atmosphere; Large scale 2.1: iron; ammonium chloride / ethanol; water / 3 h / 50 °C 3.1: hydrogenchloride; sodium nitrite / 0.5 h / -10 - -5 °C 3.2: 8 h / 0 - 25 °C
  • 11
  • [ 857784-97-5 ]
  • C12H6BrIO [ No CAS ]
YieldReaction ConditionsOperation in experiment
35% With bromine In chloroform at -40℃; for 0.5h; Inert atmosphere; 7.1 (1) Synthesis of Intermediate 7-1 10 g (34.02 mmol) of 1-iodo dibenzofuran and 2.7 g (17.01 mmol) of bromine were placed into 140 mL of chloroform under nitrogen atmosphere, and then the solution was stirred for 30 minutes at -40° C. After reaction was completed, sodium bisulfate aqueous solution was added into the solution to separate an aqueous layer from an organic layer. The organic layer was placed into anhydrous magnesium sulfate and then the organic solution was stirred again. The organic solution was filtered with a silica pad, concentrated under reduced pressure and then purified by column chromatography to give 4.4 g (yield: 35%) of Intermediate 7-1.
  • 12
  • [ 857784-97-5 ]
  • C24H13BrO2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: bromine / chloroform / 0.5 h / -40 °C / Inert atmosphere 2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / tetrahydrofuran; water / 12 h / 80 °C
  • 13
  • [ 857784-97-5 ]
  • C36H21NO2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: bromine / chloroform / 0.5 h / -40 °C / Inert atmosphere 2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / tetrahydrofuran; water / 12 h / 80 °C 3: sodium t-butanolate; bis(tri-t-butylphosphine)palladium(0) / toluene / 12 h / 110 °C
  • 14
  • [ 857784-97-5 ]
  • [ 5467-74-3 ]
  • 1-(4-bromophenyl)dibenzo[b,d]furan [ No CAS ]
YieldReaction ConditionsOperation in experiment
85% With tetrakis-(triphenylphosphine)-palladium; tetrabutylammonium bromide; potassium carbonate In ethanol; lithium hydroxide monohydrate; toluene at 105 - 110℃; for 12h; Inert atmosphere; Synthesis of intermediate i1: Combine 1-iododibenzofuran (20.9 g; 71.0 mmol), p-bromophenylboronic acid (15.0 g; 74.6 mmol), palladium tetrakistriphenylphosphine (1.6 g; 1.4 mmol), potassium carbonate (19.6 g; 142.1 mmol) ), tetrabutylammonium bromide (4.6 g; 14.2 mmol), toluene (160 mL), water (40 mL), and ethanol (40 mL) were added to the round-bottomed flask, and the reaction was stirred at 105-110 °C for 12 hours under nitrogen protection; Drop to room temperature, the reaction solution is washed with water and then liquid-separated, the organic phase is dried with anhydrous magnesium sulfate, and the solvent is removed under reduced pressure to obtain a crude product; The crude product was purified by silica gel column chromatography with dichloromethane/n-heptane as eluent to give white solid compound intermediate i1 (19.5 g; 85%)
  • 15
  • [ 857784-97-5 ]
  • [ 2891838-07-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux
  • 16
  • [ 857784-97-5 ]
  • [ 2891838-08-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux 3.1: triphenylphosphine / 1,2-dichloro-benzene / 21 h / Inert atmosphere; Reflux
  • 17
  • [ 857784-97-5 ]
  • [ 2891838-09-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux 3.1: triphenylphosphine / 1,2-dichloro-benzene / 21 h / Inert atmosphere; Reflux 4.1: tri tert-butylphosphoniumtetrafluoroborate; sodium t-butanolate; palladium diacetate / toluene / 5 h / Inert atmosphere; Reflux
  • 18
  • [ 857784-97-5 ]
  • [ 2891833-04-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 5 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux 3.1: triphenylphosphine / 1,2-dichloro-benzene / 21 h / Inert atmosphere; Reflux 4.1: tri tert-butylphosphoniumtetrafluoroborate; sodium t-butanolate; palladium diacetate / toluene / 5 h / Inert atmosphere; Reflux 5.1: sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 7 h / Inert atmosphere; Reflux
  • 19
  • [ 857784-97-5 ]
  • [ 2891838-65-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux
  • 20
  • [ 857784-97-5 ]
  • [ 2891838-66-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux 3.1: triphenylphosphine / 1,2-dichloro-benzene / 21 h / Inert atmosphere; Reflux
  • 21
  • [ 857784-97-5 ]
  • [ 2891838-67-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux 3.1: triphenylphosphine / 1,2-dichloro-benzene / 21 h / Inert atmosphere; Reflux 4.1: tri tert-butylphosphoniumtetrafluoroborate; sodium t-butanolate; palladium diacetate / toluene / 5 h / Inert atmosphere; Reflux
  • 22
  • [ 857784-97-5 ]
  • [ 2891836-44-3 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 5 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 5 h / 20 °C / Inert atmosphere 1.3: 2 h / 120 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / toluene; water; ethanol / 3 h / Inert atmosphere; Reflux 3.1: triphenylphosphine / 1,2-dichloro-benzene / 21 h / Inert atmosphere; Reflux 4.1: tri tert-butylphosphoniumtetrafluoroborate; sodium t-butanolate; palladium diacetate / toluene / 5 h / Inert atmosphere; Reflux 5.1: sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 7 h / Inert atmosphere; Reflux
  • 23
  • [ 857784-97-5 ]
  • [ 2142-63-4 ]
  • [ 2891837-99-1 ]
YieldReaction ConditionsOperation in experiment
77 % Stage #1: 1-iododibenzofuran With n-butyllithium In tetrahydrofuran; hexane at -78℃; Inert atmosphere; Stage #2: 1-(3-Bromophenyl)ethanone In tetrahydrofuran; hexane at 20℃; Inert atmosphere; Stage #3: With hydrogenchloride; acetic acid In water at 120℃; Inert atmosphere; 2 Synthesis Example 2: Synthesis of Intermediates c-24, c-26, c-42, c-51, c-90, c-114, c-252, c-262, c-302, c-332 General procedure: Under the protection of argon, add 315mL of anhydrous tetrahydrofuran solution dissolved in a-24 (56.76g, 193.00mmol) into the reaction flask, stir at -78°C,Then, 122 mL of 1.58 M n-butyl lithium in hexane was added dropwise,After stirring for 3 hours,Add 383 mL of b-24 (31.85 g, 160.00 mmol) anhydrous tetrahydrofuran solution dropwise into the reaction flask, and continue to stir for 2 hours.and stirred at room temperature for 3 hours. After the reaction was over, add 1N aqueous hydrochloric acid solution to the reaction solution and stir for 1 hour, add distilled water to the reaction solution, collect the organic phase to concentrate by distillation under reduced pressure, add glacial acetic acid (225mL) and hydrochloric acid (11mL) to the mixture obtained, and Heated and stirred at 120°C for 2 hours. After the reaction, the reaction solution was placed in an ice-water bath to precipitate a solid product, filtered, washed with methanol and dried to obtain intermediate c-24 (43.02 g, yield 77%). HPLC purity≧99.68%,
  • 24
  • [ 857784-97-5 ]
  • [ 2891817-18-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 2 h / -78 - 20 °C / Inert atmosphere 2.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; toluene; ethanol / 12 h / Inert atmosphere; Reflux 3.1: palladium diacetate; 3-nitropyridine; 1,3-dimethyl-2-imidazolidinone; tert-Butyl perbenzoate / benzene / 90 °C 4.1: sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 5 h / Inert atmosphere; Reflux
  • 25
  • [ 857784-97-5 ]
  • [ 2891821-92-2 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 2 h / -78 - 20 °C / Inert atmosphere 2.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; toluene; ethanol / 12 h / Inert atmosphere; Reflux
  • 26
  • [ 857784-97-5 ]
  • [ 2891821-93-3 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / -78 °C / Inert atmosphere 1.2: 2 h / -78 - 20 °C / Inert atmosphere 2.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; toluene; ethanol / 12 h / Inert atmosphere; Reflux 3.1: palladium diacetate; 3-nitropyridine; 1,3-dimethyl-2-imidazolidinone; tert-Butyl perbenzoate / benzene / 90 °C
  • 27
  • [ 1016-77-9 ]
  • [ 857784-97-5 ]
  • [ 2101234-40-4 ]
YieldReaction ConditionsOperation in experiment
63 % Stage #1: 1-iododibenzofuran With n-butyllithium In tetrahydrofuran; hexane at -78℃; Inert atmosphere; Stage #2: 3-bromobenzophenone In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere; Under the protection of nitrogen, 200 mL of d-8 (36.76 g, 125.00 mmol) in anhydrous tetrahydrofuran solution was added to the reaction flask, stirred at -78 ° C, and then 58 mL of 1.58 M n-butyllithium was added dropwise After stirring and reacting for 3 hours, 250 mL of e-8 (31.33 g, 120.00 mmol) in anhydrous tetrahydrofuran solution was added dropwise into the reaction flask, stirring was continued for 2 hours, and stirred at room temperature for 3 hours. After the reaction was over, add 1M aqueous hydrochloric acid solution to the reaction solution and stir for 1 hour, add distilled water to the reaction solution, collect the organic phase to concentrate by distillation under reduced pressure, add glacial acetic acid (150mL) and hydrochloric acid (8mL) to the mixture obtained, and The reaction was stirred at 120°C for 3 hours. After the reaction, the reaction solution was placed in an ice-water bath to precipitate a solid product, which was filtered, washed with methanol and dried to obtain intermediate I-8 (31.09 g, yield 63%). HPLC purity≧99.68%,
  • 28
  • [ 857784-97-5 ]
  • [ 606-21-3 ]
  • [ 2927513-82-2 ]
YieldReaction ConditionsOperation in experiment
32 % With copper at 120℃; Schlenk technique; Inert atmosphere;
  • 29
  • [ 857784-97-5 ]
  • [ 2927513-83-3 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: copper / 120 °C / Schlenk technique; Inert atmosphere 2: platinum(IV) oxide; hydrogen / 1,4-dioxane; ethanol / 20 °C
  • 30
  • [ 857784-97-5 ]
  • [ 2928472-67-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1: copper / 120 °C / Schlenk technique; Inert atmosphere 2: platinum(IV) oxide; hydrogen / 1,4-dioxane; ethanol / 20 °C 3: palladium diacetate; tricyclohexylphosphine; potassium hydroxide / toluene / 110 °C / Schlenk technique; Inert atmosphere 4: 4-chloro-benzenesulfonic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere
  • 31
  • [ 857784-97-5 ]
  • [ 2927513-57-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: copper / 120 °C / Schlenk technique; Inert atmosphere 2: platinum(IV) oxide; hydrogen / 1,4-dioxane; ethanol / 20 °C 3: palladium diacetate; tricyclohexylphosphine; potassium hydroxide / toluene / 110 °C / Schlenk technique; Inert atmosphere
  • 32
  • [ 857784-97-5 ]
  • [ 2928472-67-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1: copper / 120 °C / Schlenk technique; Inert atmosphere 2: platinum(IV) oxide; hydrogen / 1,4-dioxane; ethanol / 20 °C 3: palladium diacetate; tricyclohexylphosphine; potassium hydroxide / toluene / 110 °C / Schlenk technique; Inert atmosphere 4: 4-chloro-benzenesulfonic acid; C37H40NO4PSe / dichloromethane; tert-butyl methyl ether / 18 h / -80 °C / Inert atmosphere
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