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Chemical Structure| 860002-66-0 Chemical Structure| 860002-66-0

Structure of 860002-66-0

Chemical Structure| 860002-66-0

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Product Details of [ 860002-66-0 ]

CAS No. :860002-66-0
Formula : C15H12IN3
M.W : 361.18
SMILES Code : IC1=C(C2=CC=CC=C2)N=NN1CC3=CC=CC=C3

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Application In Synthesis of [ 860002-66-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 860002-66-0 ]

[ 860002-66-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 860002-66-0 ]
  • [ 214360-70-0 ]
  • C19H15N3S [ No CAS ]
YieldReaction ConditionsOperation in experiment
68% With bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; In neat (no solvent); at 110℃; for 24h;Green chemistry; General procedure: A screw cap vial equipped with a magnetic stirring bar was charged with the corresponding 4- or 5-halo-1,2,3-triazole (0.5 mmol, 1.0 equiv.), ArBPin (0.525 mmol, 1.05 equiv.), Pd(OAc)2 (0.005 mmol, 0.01 equiv.), SPhos (0.01 mmol, 0.02 equiv.), and powdered 85% KOH (0.85 mmol, 1.7 equiv.). All the components were thoroughly mixed together. The vialwas placed into a preheated oil bath (110 C). After 24 h, the reaction mixture was cooled and treated with CH2Cl2-H2O (1 : 1) mixture, theorganic phase was separated and the solvent was evaporated in vacuo. Thepure product was isolated by silica gel chromatography using hexane-EtOAc (10 :1) mixture as eluent.
 

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