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Chemical Structure| 862159-27-1 Chemical Structure| 862159-27-1

Structure of 862159-27-1

Chemical Structure| 862159-27-1

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Product Details of [ 862159-27-1 ]

CAS No. :862159-27-1
Formula : C15H16B2O5
M.W : 297.91
SMILES Code : CC1(C)C2=C(OC3=C1C=CC=C3B(O)O)C(B(O)O)=CC=C2

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Application In Synthesis of [ 862159-27-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 862159-27-1 ]

[ 862159-27-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 862159-27-1 ]
  • [ 33172-56-4 ]
  • C23H21BO5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; water; at 80℃; for 12h;Schlenk technique; Inert atmosphere; Under the protection of nitrogen, <strong>[33172-56-4]5-bromo-2-hydroxy-3-methylbenzaldehyde</strong>(1.02g, 4.7mmol), [5-(dihydroxyboranyl)-9,9-dimethyl-9H-xanthen-4-yl]boronic acid 1 (1.5g, 4.7mmol),Potassium carbonate (1.62g, 11.75mmol) and tetrakis (triphenylphosphine) palladium (271mg, 0.235mmol) were added to the Schlenk bottle,Add redistilled THF (80 mL) and N2 bubbled H2O (30 mL),Heated to 80 C for 12 hours. Cool to room temperature,The organic solvent was removed by rotary evaporation, followed by extraction with dichloromethane,It was washed with water and saturated saline, separated, and dried over anhydrous sodium sulfate. After the filtrate was spin-dried, the crude product was separated and purified with a silica gel column. The developing solvent was petroleum ether / ethyl acetate (20: 1, v / v) to obtain product 2a as a white solid (1.30 g, 70%).
 

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