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Chemical Structure| 867164-87-2 Chemical Structure| 867164-87-2

Structure of 867164-87-2

Chemical Structure| 867164-87-2

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Product Details of [ 867164-87-2 ]

CAS No. :867164-87-2
Formula : C14H9ClN2
M.W : 240.69
SMILES Code : ClC1=CC2=NC(C3=CC=CC=C3)=NC=C2C=C1
MDL No. :MFCD27922427

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Application In Synthesis of [ 867164-87-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 867164-87-2 ]

[ 867164-87-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 37585-16-3 ]
  • [ 100-46-9 ]
  • [ 867164-87-2 ]
  • 2
  • [ 37585-16-3 ]
  • [ 100-47-0 ]
  • [ 867164-87-2 ]
YieldReaction ConditionsOperation in experiment
65% With C39H32Cl2N5PRu; potassium tert-butylate; In tert-Amyl alcohol; at 130℃; for 2h;Sealed tube; General procedure: To an oven-dried 15 mL sealed tube were added 2-aminophenylmethanol 1 (0.425 mmol), benzonitrile 2(0.25 mmol), Ru cat. b (1.94 mg, 1 mol%), and KOtBu (14.02 mg, 0.5equiv) intamyl alcohol (1 mL) under an air atmosphere. The sealedtube was capped and heated at 130C for 2 h. The reaction mixturewas cooled down to room temperature and directly concentratedunder vacuum. The crude mixture was puried by preparative thin-layer-chromatography (petroleum ether/ethyl acetate 20/1) togive the desired product 3 or 4.
 

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