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Chemical Structure| 867291-46-1 Chemical Structure| 867291-46-1

Structure of 867291-46-1

Chemical Structure| 867291-46-1

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Product Details of [ 867291-46-1 ]

CAS No. :867291-46-1
Formula : C15H23N3
M.W : 245.37
SMILES Code : NC1=CC=C(N2CCC(N3CCCC3)CC2)C=C1

Safety of [ 867291-46-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 867291-46-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 867291-46-1 ]

[ 867291-46-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 867291-46-1 ]
  • [ 17823-69-7 ]
  • [ 1456732-94-7 ]
YieldReaction ConditionsOperation in experiment
Dissolved 0.500 g <strong>[17823-69-7]2-cyano-3,3-bis(methylthio)acrylamide</strong> in 15 mL EtOH and added l-(4-aminophenyl)-4-(l-pyrrolidinyl)piperidine (1.0 eq.) . Stirred reaction at 75 C until starting amide was absent by HPLC. Once complete (18 hrs), reaction was brought to room temperature and filtered to obtain a light yellow powder as product. Product was allowed to dry under vacuum for 1 hr. Product was then suspended in 10 mL EtOH and hydrazine hydrate (1 eq.) was added dropwise. Reaction was heated at 75 C until intermediate was absent (HPLC). Once intermediate was absent (18 hrs), reaction was brought to room temperature and filtered to obtain 5 -amino-3 -((4-(4-(pyrrolidin-l- yl)piperidin-l-yl)phenyl)amino)-lH-pyrazole-4-carboxamide as a yellow powder. Product was allowed to dry under vacuum for 1 hr. 5 -amino-3 -((4-(4-(pyrrolidin- 1 -y l)piperidin- 1 -yl)phenyl)amino)- 1 H-pyrazole-4-carboxamide
 

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