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Chemical Structure| 871723-37-4 Chemical Structure| 871723-37-4

Structure of 871723-37-4

Chemical Structure| 871723-37-4

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Product Details of [ 871723-37-4 ]

CAS No. :871723-37-4
Formula : C8H6ClNO
M.W : 167.59
SMILES Code : ClC1=C2CNC(=O)C2=CC=C1
MDL No. :MFCD09701291
InChI Key :UCZAYZNTAWBJRF-UHFFFAOYSA-N
Pubchem ID :53404273

Safety of [ 871723-37-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 871723-37-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 871723-37-4 ]

[ 871723-37-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 188187-03-3 ]
  • [ 871723-37-4 ]
YieldReaction ConditionsOperation in experiment
92% With ammonia; In methanol; at 20℃; for 7h;Heating / reflux; Compound 1193 (6.31 g, 0.0239 mol) was dissolved in 7 N NH3 in MeOH (50 mL) and stirred at room temperature for 3 h then heated at reflux for 4 h. The reaction mixture was cooled to room temperature and concentrated. The residue was suspended in CH2Cl2 (150 mL), and the solid was removed by filtration and washed with CH2Cl2. The filtrate was concentrated, and the crude product was purified by silica gel flash chromatography (eluant: 5% MeOH-CH2CI2 to 10% MeOH-CH2Cl2) to give 3.68 g (92%) of the product 1196 as a white solid. MS for M+1: 168.
 

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Technical Information

• Acyl Group Substitution • Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Chan-Lam Coupling Reaction • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

Categories

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