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Chemical Structure| 874-20-4 Chemical Structure| 874-20-4

Structure of 874-20-4

Chemical Structure| 874-20-4

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Product Details of [ 874-20-4 ]

CAS No. :874-20-4
Formula : C5H6ClN3O
M.W : 159.57
SMILES Code : O=C1N(C)C(N)=NC(Cl)=C1
MDL No. :MFCD20697747

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Application In Synthesis of [ 874-20-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 874-20-4 ]

[ 874-20-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1194-21-4 ]
  • [ 74-88-4 ]
  • [ 874-20-4 ]
YieldReaction ConditionsOperation in experiment
To a suspension OF 2-AMINO-6-CHLOROPYRIMIDIN-4 (3H)-ONE (5.37 g) in ethanol (300 mL) was added NAOH (S) (1.94 g) and heated (Tb= 60 °C). After 30 MIN., iodomethane (3.0 mL) was added and the reaction heated to reflux. After 2h, additional NAOH (S) (2.36 g) and iodomethane (1.5 mL) were added. After 7 h, the reaction was concentrated. The residue was diluted with water and neutralized with acetic acid. The resulting solid was collected by filtration yielding 2.43 g white solid after drying on high vacuum.
 

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