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Chemical Structure| 87491-79-0 Chemical Structure| 87491-79-0

Structure of 87491-79-0

Chemical Structure| 87491-79-0

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Product Details of [ 87491-79-0 ]

CAS No. :87491-79-0
Formula : C11H9ClO2S
M.W : 240.71
SMILES Code : O=S(C1=C2C=CC=CC2=CC=C1)(CCl)=O
MDL No. :MFCD11100779

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Application In Synthesis of [ 87491-79-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 87491-79-0 ]

[ 87491-79-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 16155-03-6 ]
  • [ 87491-79-0 ]
  • [ 1199795-12-4 ]
YieldReaction ConditionsOperation in experiment
87% With potassium tert-butylate; In tetrahydrofuran; at -78 - 20℃; To a stirred mixture of <strong>[16155-03-6]1-methyl-4-(4-nitrophenyl)piperazine</strong> (4.00 g, 18.1 mmol) and 1-(chloromethylsulfonyl)naphthalene (4.35 g, 18.1 mmol) in THF (40 mL) at -78 C. was slowly added KOtBu (1 M in THF, 40 mL). The stirred mixture was allowed to warm to room temperature for 2 hours, quenched with water, and concentrated. The residue was taken into water and extracted with EtOAc. The organic layer was dried over Na2SO4, and concentrated in vacuo to provide the title compound (6.70 g, 87%), characterized by NMR and mass spectral analyses. MS (ES+) m/e 426 (MH+).
 

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