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Chemical Structure| 885519-58-4 Chemical Structure| 885519-58-4

Structure of 885519-58-4

Chemical Structure| 885519-58-4

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Product Details of [ 885519-58-4 ]

CAS No. :885519-58-4
Formula : C7H4Cl2N2
M.W : 187.03
SMILES Code : ClC1=CC(Cl)=C2C=NNC2=C1
MDL No. :MFCD07781384
InChI Key :KTTXUMXAFXKIMN-UHFFFAOYSA-N
Pubchem ID :24728132

Safety of [ 885519-58-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 885519-58-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 885519-58-4 ]

[ 885519-58-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 24473-00-5 ]
  • [ 885519-58-4 ]
YieldReaction ConditionsOperation in experiment
38% With hydrazine; In 1,4-dioxane; at 160.0℃; for 0.5h;Microwave irradiation; Sealed tube; In a microwave vial 2,4,6-trichlorobenzaldehyde (4.0 g, 19.1 mmol) was dissolved in 1 ,4- dioxane (8 mL) and hydrazine (7.2 mL, 229 mmol) was added. The vial was sealed and heated under microwave irradiation at 160C for 30 min. The reaction was quenched with water and extracted with EtO Ac. The organic layer was washed with brine then dried over MgS04 and concentrated. The residue was purified by silica gel chromatography with 50% to 100%EtO Ac/heptane to provide 1.38 g (38%) of 4,6-dichloro-lH-indazole as a white solid. 1H NMR(CDCls, 300 MHz): ? (ppm) 8.14 (s, 1H), 7.44 (s, 1H), 7.20 (d, J=1.5 Hz, 15H).
  • 2
  • [ 108-70-3 ]
  • [ 885519-58-4 ]
 

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[ 885519-58-4 ]

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