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Chemical Structure| 887365-58-4 Chemical Structure| 887365-58-4

Structure of 887365-58-4

Chemical Structure| 887365-58-4

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Product Details of [ 887365-58-4 ]

CAS No. :887365-58-4
Formula : C8H9N5
M.W : 175.19
SMILES Code : NC1=NNC(N)=C1C2=NC=CC=C2
MDL No. :MFCD20724351

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Application In Synthesis of [ 887365-58-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 887365-58-4 ]

[ 887365-58-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 887365-58-4 ]
  • [ 80370-42-9 ]
  • 2-amino-3-pyridin-2-yl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
61% acetic acid; at 180℃; for 0.25h;Microwave irradiation; Example 8 [0286] 2-Amino-3-pyridm-2-yl-pyrazolo[1,5-a]pyrimidine-6-carboxyIic acid ethyl ester IV-1A mixture of 4-(pyridin-2-yl)-lH-pyrazole-3,5-diamine (0.10 g, 0.57 mmol), <strong>[80370-42-9](ethoxycarbonyl)malondialdehyde</strong> ( 0.084 g, 0.57 mmol) and 2 drops acetic acid in 1- propanol (3 mL) was heated in the microwave for 15 min at 180°C with stirring. The reaction was cooled down to room temperature and filtered, washing with ethanol and vacuum dried at 60°C for 3 days to provide the title compound as a brown solid (0.098 g, 61 percent yield). MS (ES+) 284. deltaEta (500 Mhz, DMSO-d6) 1.35 (3Eta, t), 4.36 (2H, q), 7.19 (1H, m), 7.36 (2H, s), 7.87 (1H, dt), 8.58 (2H, m), 8.82 (1H, d), 9.18 (1H, d)
 

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