Home Cart Sign in  
Chemical Structure| 888484-99-9 Chemical Structure| 888484-99-9

Structure of 888484-99-9

Chemical Structure| 888484-99-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 888484-99-9 ]

CAS No. :888484-99-9
Formula : C4H2Br2N2O
M.W : 253.88
SMILES Code : O=CC1=C(Br)NN=C1Br
MDL No. :MFCD14706480

Safety of [ 888484-99-9 ]

Application In Synthesis of [ 888484-99-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 888484-99-9 ]

[ 888484-99-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 888484-99-9 ]
  • [ 1700-31-8 ]
  • 1-(3-(benzyloxy)benzyl)-3,5-dibromo-1H-pyrazole-4-carbaldehyde [ No CAS ]
YieldReaction ConditionsOperation in experiment
57% With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20℃; for 12h; To a mixture of 3,5-dibromo-1H-pyrazole-4-carbaldehyde (21) (25.0 g, 99.3 mmol, 80percent purity) in DMF (200 mL) was added K2CO3 (32.7 g, 237 mmol) and 1-(benzyloxy)-3- (bromomethyl)benzene (22) (22.9 g, 82.6 mmol) at 0 °C, and then it was stirred at 16?20 °C for 12 h. Then the mixture was diluted with water and the mixture was extracted with EtOAc. The combined organic layers were washed with water, dried over Na2SO4 and concentrated under reduced pressure. The residue was purified by column chromatography on silica gel (eluted with EtOAc in petroleum ether) to give 1-(3-(benzyloxy)benzyl)-3,5-dibromo-1H-pyrazole-4-carbaldehyde (23) (19.8 g, 44.2 mmol, 57percent) as an off-white solid. 1H NMR (400 MHz, CDCl3) delta 5.05 (s, 2H), 5.33 (s, 2H), 6.80?6.90 (m, 2H), 6.94 (dd, J = 8.0, 1.6 Hz, 1H), 7.24?7.45 (m, 6H), 9.76 (s, 1H).
 

Historical Records