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[ CAS No. 88938-12-9 ]

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Chemical Structure| 88938-12-9
Chemical Structure| 88938-12-9
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CAS No. :88938-12-9 MDL No. :MFCD04038046
Formula : C27H22O2 Boiling Point : 533.40°C at 760 mmHg
Linear Structure Formula :- InChI Key :-
M.W :378.46 g/mol Pubchem ID :-
Synonyms :

Safety of [ 88938-12-9 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 88938-12-9 ]

  • Downstream synthetic route of [ 88938-12-9 ]

[ 88938-12-9 ] Synthesis Path-Downstream   1~15

  • 1
  • [ 88938-12-9 ]
  • [ 943722-36-9 ]
  • [ 383-29-9 ]
  • polymer; monomer(s): bis(4-fluorophenyl)sulfone; 9,9-bis(4-hydroxy-3-methylphenyl)fluorene; propyl-carbamic acid 3,5,3\,,5\-tetramethyl-4\-propylcarbamoyloxy-biphenyl-4-yl ester [ No CAS ]
  • 2
  • [ 88938-12-9 ]
  • [ 383-29-9 ]
  • polymer; monomer(s): bis(4-fluorophenyl)sulfone; 9,9-bis(4-hydroxy-3-methylphenyl)fluorene [ No CAS ]
  • 3
  • [ 75-21-8 ]
  • [ 88938-12-9 ]
  • [ 156326-34-0 ]
  • C33H34O5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
1: 99.2 %Chromat. 2: 0.8 %Chromat. In 2-methoxy-ethanol at 100℃; for 10h; 12; 13 EXAMPLE 12 [0155] Reaction of adding EO to biscresol fluorene (BCF) as a multivalent phenol was carried out in the similar manner as in Example 1 except for the following. Specifically, into an autoclave, charged was 100 g of BCF, with addition of 200 g of ethyleneglycol monomethyl ether (δ=11.4), and 10.0 g of anion exchange resin A (Cl-type dried material), and the autoclave was sealably closed. Next, 29.1 g of EO was added to the mixture, and the mixture was aged in the autoclave at 100° C. for 10 hours. After the aging, the anion exchange resin A was separated from the reaction solution by filtration. [0156] The composition of the reaction solution was analyzed according to LC. The LC analyzing conditions were the same as in Example 3 except for the use of 0.1% by mass of the mixed solution of phosphoric acid and methanol (35:65 in volume ratio). A result of LC analysis on the composition of the reaction solution reveals that all the raw material BCF was converted (inversion rate is 100%), and the content of BCF-2EO adduct was 96.3%, and the content of BCF-3EO adduct was 3.4%, respectively. No BCF-LEO adduct was detected. BCF-1EO adduct is ether obtained by reaction of either one of two hydroxyl groups in BCF with one EO molecule. BCF-2EO adduct is ether obtained by reaction of both of two hydroxyl groups in BCF with two EO molecules. BCF-3EO adduct is ether in which one of two hydroxyl groups in BCF is reacted with one EO molecule, whereas the other one of the two hydroxyl groups in BCF is reacted with two EO molecules. [0157] EXAMPLE 13; Crystallization-purification of the reaction solution obtained in Example 12 was carried out. Into a separable flask equipped with a stirrer, a cooling device, and a thermometer, charged was a solution for crystallization, which is the reaction solution obtained in Example 12. The flask was heated in an oil bath at 95° C. Next, the solution was cooled from 95° C. to 40° C. at a cooling rate of 5° C./hour while stirring the solution at 200 rpm. As a result of stirring, the solution was turned into a slurry having fluidity in its entirety. Then, the slurry was retained at 40° C. for 1 hour. Thus, crystallization was terminated. The slurry was subjected to filtration, and the filtrate was washed with 40 g of ethylene glycol monomethyl ether at normal temperature. Then, the filtrate was depressurized and dried at 60° C., thereby yielding the purified product. As is the case of Example 12, a result of LC analysis on the composition of the purified product reveals that the content of BCF-2EO adduct was 99.2%, the content of BCF-3EO adduct was 0.8%, respectively, and the yield of BCF-2EO adduct was 60%.
  • 4
  • fluorenone [ No CAS ]
  • [ 95-48-7 ]
  • [ 88938-12-9 ]
YieldReaction ConditionsOperation in experiment
89% With hydrogenchloride; 3-mercaptopropionic acid In water at 25 - 35℃; for 17h; 1 Example 1 In a 2 L glass vessel equipped with a stirrer, a cooler and a thermometer were charged fluorenone (75g) having a purity of 99% by weight, o-cresol (270g), β-mercaptopropionic acid (8.5g), and 36% by weight of hydrochloric acid aqueous solution (27g). The mixture was subjected to a reaction with stirring under an atmosphere of an inert gas at 25°C for 6 hours, followed by at 35°C for 11 hours. The analysis of the reaction product by HPLC showed that the remaining amount of fluorenone was not more than 0.1% by weight. After toluene (300g) and water (80g) were added to the resultant reaction solution, an aqueous solution containing sodium hydroxide (32% by weight) was added to the mixture for neutralization to approximately pH 7, then the resulting water layer was removed. The organic layer was heated to 80°C, and washed with water (80g) three times. After collecting toluene (300g) by distillation under a reduced pressure, a mixture (500 ml) containing toluene and acetone at a mixing ratio (weight ratio) [toluene/acetone] of 1/4 was added to the organic layer, and stirred at 70°C for one hour. Then, the resultant mixture was cooled to 10°C for crystallization to give an object product, 9,9-bis(4-hydroxy-3-methylphenyl)fluorene (140g, yield 89%). The purity of thus obtained fluorene derivative was 99.6% by weight. Moreover, the b value was 1.3 (colorless and transparency). The fluorene derivative can be therefore used as a raw material of polymer without further crystallization operation.
76% With hydrogenchloride; 3-mercaptopropionic acid at 50℃; for 4h; 1 Comparative Example 1 In a 2 L glass vessel equipped with a stirrer, a cooler, a thermometer and a tube for supplying hydrogen chloride gas were charged fluorenone (75g) having a purity of 99% by weight, o-cresol (160g), and ?-mercaptopropionic acid (2g), and fluorenone was completely dissolved in the mixture with stirring and heating at 50C under an atmosphere of an inert gas. A hydrogen chloride gas was passed through the mixture at a feed rate of 200 ml/minute, and initiated the reaction. The reaction was continued for 4 hours with maintaining the reaction temperature of 50C. After complication of the reaction, a nitrogen gas was passed through the reaction mixture at a feed rate of 5 L/minute for 30 minutes to drive out the remaining hydrogen chloride gas in the vessel. After toluene (300g) and water (80g) were added to thus obtained reaction solution, an aqueous solution containing sodium hydroxide of 32% by weight was added to the mixture for neutralization to approximately pH 7, then the water layer was removed. The organic layer was heated to 80C, and washed with water (80g) three times. After collecting toluene (300g) by distillation under a reduced pressure, a mixture (500 ml) containing toluene and acetone at a mixing ratio [toluene/acetone] of 1/4 (weight ratio) was added to the organic layer, and stirred at 70C for one hour. Thereafter, the resultant mixture was cooled to 10C for crystallization to give an object product, 9,9-bis(4-hydroxy-3-methylphenyl)fluorene (120g, yield 76%). The purity of the resulting fluorene derivative was 95.2% by weight. Moreover, the b value was 12.5 (light yellow), and it was necessary to operate crystallization further 3 times under the same conditions in order to obtain the fluorene derivative having the b value of not more than 3 which was required to use as a raw material for a polymer.
  • 5
  • [ 486-25-9 ]
  • [ 95-48-7 ]
  • [ 107-96-0 ]
  • [ 88938-12-9 ]
YieldReaction ConditionsOperation in experiment
In water; toluene E.5 Preparation of 9,9-Bis(4-hydroxy-3-methylphenyl)fluorene EXAMPLE E-5 Preparation of 9,9-Bis(4-hydroxy-3-methylphenyl)fluorene The following procedure is employed to prepare 9,9-bis(4-hydroxy-3-methylphenyl)fluorene, which may be represented by the following structure: STR4 To a stirred mixture of fluorenone (18 g; 0.1 mole), o-cresol (57.5 g, 0.53 mole), and sulfated zirconium oxyhydroxide catalyst E-1 (15 g) is added 0.3 ml of 3-mercaptopropionic acid. The mixture is stirred and heated at 85° C. for 3 hr. Analysis by gas chromatography gives the results set forth in Table I. It is seen that the sulfated zirconium oxyhydroxide catalyst is capable of catalyzing the condensation of fluorene with cresol, the cresol conversion being greater than 95 percent and the selectivity for 9,9-bis(4-hydroxy-3-methylphenyl)fluorene being 98 mole percent. The reaction mixture is cooled, and 100 ml each of toluene and water are added. The catalyst is filtered off. The filtrate is concentrated on a rotary evaporator to remove an o-cresol/water azeotropic mixture. Water, 100 ml, is added to the residue, and the o-cresol/water azeotrope is distilled off a second time. The addition of water and distillation are repeated two more times, and then the residue is dissolved in 100 ml of boiling toluene. On cooling, 9,9-bis(4-hydroxy-3-methylphenyl)fluorene crystallizes as white crystals which are separated by filtration and washed with hexane (29.9 g; mp 214°-217° C.; 79 mole percent isolated yield). Concentration of the filtrate provided a second crop of product (3.0 g) for a total isolated yield of 87 mole percent; GC purity is greater than 99 percent.
  • 6
  • [ 486-25-9 ]
  • [ 95-48-7 ]
  • [ 88938-12-9 ]
YieldReaction ConditionsOperation in experiment
92% With 3-mercaptopropionic acid In chlorobenzene at 140℃; for 6h; 1; 2; 9; 11.2 Example 9: 288g of 9-fluorenone, 600g of o-methylphenol, 200g of activated clay catalyst, 16g of 3-mercaptopropionic acid, 2500g of chlorobenzene were sequentially added to a 5KL three port equipped with a stirrer, thermometer and water separator (with condenser) In the flask, the mixture was stirred, heated to reflux (140 ° C) and separated by water, and reacted for 6 hours. After the reaction, the mixture was filtered while hot, and the residue was recovered at 120 ° C for the next reaction. The filtrate was cooled to 10 ° C and then incubated for 1 hour. A crude gray product was obtained, which was recovered and used in the next reaction of the product; the crude product was recrystallized from toluene-methanol to give a white solid, 9,9-bis(3-methyl-4-hydroxyphenyl)indole product, 556.4 g. The yield was 92%, and the melting point was 218.6 to 220.2 ° C, and the HPLC purity was 99.5%.
84.3% With hydrogenchloride In water; toluene at 50℃; for 2h; 3 Example 3 A reaction was carried out by feeding 23 g of fluorenone, 1.3 g of dodecyl mercaptan, and 161.0 g of 2-methyl phenol into a 500 ml glass reactor vessel equipped with a stirrer, a condenser and a thermometer, (b) dropping 13.0 g of 35% hydrochloric acid to a mixture, and (c) stirring the mixture at 50° C. for 2 hours. The amount of remaining fluorenone was determined by HPLC, and found to be 0.1% or less. To an obtained reaction mixture liquid, 18.5 g of 29% sodium hydroxide aqueous solution was added, and thereafter 94.0 g of 2-methyl phenol was distilled away from an organic phase by concentration under reduced pressure. To an obtained concentrated liquid, 161 g of toluene and 23 g of water were added, and the mixture liquid was stirred at 80° C. Thereafter, an aqueous phase was separated and removed, and a target substance partitioned in the organic phase was recovered. The organic phase was further washed twice with 23 g of water, and cooled to 10° C. Then, precipitated crystals were subjected to filtration and drying to obtain 37.9 g of 9,9-bis(4-hydroxy-3-methylphenyl)fluorene (yield: 84.3%, LC purity: 99.3%). Obtained 9,9-bis(4-hydroxy-3-methylphenyl)fluorene was dissolved by heat at 230° C. for 2 hours. The 9,9-bis(4-hydroxy-3-methylphenyl)fluorene thus dissolved had a hue of 1 in Gardner. The total amount of toluene used in the production was 4.2 parts by weight relative to 1 part by weight of the 9,9-bis(4-hydroxy-3-methylphenyl)fluorene.
39 g With hydrogenchloride; 1-dodecylthiol at 40 - 45℃; for 4h; Inert atmosphere; 1 Synthesis Example 1 Synthesis of A- 19 gand 1.0 g of water were put into 1 L of a three-neck flask including a thermometer, a stirring blade, a dropping funnel, and a reflux cooling pipe, nitrogen substitution was performed in a system, and then, hydrogen chloride gas was blown into the system until the system was saturated at 40° C. A mixed liquid of 35.5 g of o-cresol and 23.7 g of 9-fluorenone was gradually dropped while maintaining the temperature in the system to be 40° C. to 45° C. Afier the dropping ended, a reaction was further performed at 45° C. for 4 hours. After the reaction ended, 28 g of an aqueous solution of sodium hydroxide of 12% was added, neutralization was performed, 50 g of acetone was added, and crystals were dissolved. After that, cooling was performed to a room temperature, and the educed crystals were filtered.10257] The obtained crude crystals were dissolved in alarge amount of acetone and were recrystallized, and thus, atarget compound A-i 9 was obtained (39 g, white crystals).
85.6 %Chromat. With methanol; sulfuric acid; 1-dodecylthiol In toluene at 50℃; for 2.5h; Inert atmosphere; 27 Example 27 In a full-jacket type 1 L, separable flask equipped with a thermometer, a stirrer, and 100 mL, 26 g (0.8 mol) of methanol was added under a nitrogen atmosphere, and then 58.5 g (0.5 mol) of 90% by weight sulfuric acid was slowly added thereto to provide a solution in which monomethyl sulfate was produced. Thereafter, 60 g of toluene, 197.0 g (1.8 mol) of ortho-cresol, and 5.5 g (0.03 mol) of dodecanethiol were added thereto, followed by setting the temperature in the separable flask to 50° C. Subsequently, 136 g (0.8 mol) of fluorenone was placed therein, and slowly fed dropwise to the separable flask for 30 minutes. Thereafter, the reaction was allowed to proceed at 50° C. for 2 hours. After completion of the reaction, 100.0 g of ethyl acetate and 100.0 g of demineralized water were fed, and the resulting mixture was mixed. Thereafter, the mixture was left to stand, and the aqueous phase in the lower layer, was extracted. Thereafter, saturated sodium hydrogen carbonate solution was added to the obtained organic phase to allow neutralization, followed by confirming that the pH of the aqueous phase in the lower layer, became not less than 9. After extraction of the aqueous phase in the lower layer, demineralized water was added to the obtained organic phase, and the resulting mixture was stirred for 10 minutes. Thereafter, the mixture was left to stand, and the aqueous phase was extracted. Part of the obtained organic phase was removed and subjected to measurement by high-performance liquid chromatography. As a result, production of 9,9-bis(4-hydroxy-3-methylphenyl) fluorene was found. Its production rate was 85.6% by area.

  • 7
  • [ 88938-12-9 ]
  • C37H34O8 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: water; ethanol / 2 h / 80 °C 2: 6 h / 80 °C
  • 8
  • [ 88938-12-9 ]
  • C31H30O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: water; ethanol / 2 h / 80 °C 2: 6 h / 80 °C 3: potassium carbonate / 2 h / 60 °C
  • 9
  • [ 88938-12-9 ]
  • [ 50-00-0 ]
  • [ 124-40-3 ]
  • C33H36N2O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
95% In ethanol; water at 80℃; for 2h; C-1A Synthesis of Compound (C-1A) A mixture of 18.8 g of 9,9-bis(4-hydroxy-3-methylphenyl)fluorene (manufactured by Wako Pure Chemical Industries, Ltd.), 19.8 g of a 50% aqueous dimethylamine solution, 6.6 g of paraformaldehyde, and 10 mL of ethanol was stirred at 80° C. for 2 hours. After ethanol was distilled off, 50 mL of ethyl acetate and 50 mL of water were added to the mixture to carry out liquid separation. The organic layer was washed twice with 50 mL of water. The resulting organic layer was dried over magnesium sulfate, dried and then filtered. The solvent in the filtrate was distilled off to give 23.4 g (yield: 95%) of (C-1A) as a crude product.
  • 10
  • [ 88938-12-9 ]
  • [ 1204-28-0 ]
  • C45H26O10 [ No CAS ]
YieldReaction ConditionsOperation in experiment
96.2% With pyridine; In toluene; acetonitrile; at 4 - 84℃; for 5.5h;Inert atmosphere; A thermometer, a dropping funnel, a stirrer, a 1L four-necked flask equipped with a reflux condenser was charged with 130.20 g (344.0 mmol) of 9,9-bis(4-hydroxy-3-methylphenyl)fluorenone, 166.60 g (791.2 mmol) of trimellitic anhydride chloride (hereinafter sometimes referred to as TAC) 260.28 g of acetonitrile was charged, under a nitrogen atmosphere, after stirring, cooled to 4 C. After cooling, Further, 62.63 g (791.8 mmol) of pyridine was added dropwise at 4 C. to 10 C. over 2 hours. After completion of the dropwise addition, 260.28 g of toluene was charged, after that, The temperature was raised to reflux, refluxed (internal temperature 82 to 84 C.) And the mixture was stirred for 3.5 hours. After completion of stirring, The reaction solution was measured by HPLC, The residual ratio of the raw material 9,9-bis (4-hydroxy-3-methylphenyl) fluorenone was 0.0% The formation rate of the monoester (ester formed by the reaction of 1 mole of 9,9-bis (4-hydroxy-3-methylphenyl) fluorenone and 1 mole of trimellitic anhydride) was 0.3% The formation rate of the objective tetracarboxylic acid dianhydride represented by the above formula (5) was 97.8%. After the reaction, the reaction solution was cooled to 26 C and the precipitated crystals were separated by filtration at the same temperature. After filtration, crystals was further washed four times with 260.28 g of acetonitrile, and the obtained crystals were dried under vacuum at 90 C. and dried to obtain 240.38 g of a tetracarboxylic acid dianhydride crystal represented by the above formula (5) (yield 96.2%).
  • 11
  • [ 88938-12-9 ]
  • [ 822-48-0 ]
  • 9,9-bis[4-(3-methyl-3-oxetanyl)methoxy-3-methylphenyl]fluorene [ No CAS ]
YieldReaction ConditionsOperation in experiment
95.7% With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60 - 100℃; for 13h; 2 Comparative Example 2 BCF (28.4 g, 75 mmol) was dissolved in DMF (168 g), then potassium carbonate (26.3 g, 190 mmol), KI (1.28 g, 7.7 mmol) was added and stirred at 60 ° C. To this solution, 3-chloromethyl-3-methyloxetane (24.87 g, 206 mmol) was added dropwise at 60 ° C. After completion of the dropwise addition, the mixture was heated to 80 ° C. and reacted for 5 hours, and further heated to 100 ° C. And allowed to react for 8 hours. After completion of the reaction, 525 mL of water was added, and extraction with 112 g of ethyl acetate was performed three times. Furthermore, washing with 100 g of water was carried out six times, and the obtained organic phase (ethyl acetate phase) was concentrated under reduced pressure to obtain 39.2 g (yield: 95.7%) of a compound in the form of pale orange crystals.
  • 12
  • [ 96-49-1 ]
  • [ 88938-12-9 ]
  • [ 156326-34-0 ]
YieldReaction ConditionsOperation in experiment
89.5% With potassium carbonate In toluene at 115℃; for 16h; 1 Example 1 Agitator, nitrogen injection pipe, and a temperature gauge glass reactor equipped with a cooling tube, 9,9-bis (4-hydroxy-3-methylphenyl) fluorene 60g, ethylenecarbonate 32.0g, potassium carbonate 3.0g and toluene 30g is applied, by heating and stirring time 16 115 °C 9,9-bis (4-hydroxy-3-methylphenyl) fluorene contg. bis hydroxyethyl ether 82.4% of a reaction product is obtained. The reaction product of toluene 420g, 12.0% by weight aqueous sodium hydroxide 120g, tetrabutylammonium bromide 0.9g is added, with stirring preipitated 85 °C 1 placed after separating an organic solvent phase, 5.3% by weight of the organic solvent, adding hydrochloric 120g, 15 minutes at 85 °C placed preipitated stirring, separated by an organic solvent phase, to remove a water layer containing hydrochloric acid. Water is added to the organic solvent phase 90g, 15 minutes at 85 °C placed preipitated stirring, organic solvent phase is separated from the liquid portion. The same operation is repeated twice more 2. Thereafter, the organic solvent phase after 300g concd. than toluene, cooled to 25 °C to precipitate crystals. Furthermore, the deposited crystals is filtered, dried, 9,9-bis (4 - (2-ethoxy) - 3-methylphenyl) fluorene crystal 66.2g (yield 89.5%) is obtained. The obtained white crystals, 96.1% purity.
  • 13
  • [ 88938-12-9 ]
  • [ 814-68-6 ]
  • C33H26O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 4-methoxy-phenol; triethylamine In toluene at 25℃; for 2h; 4 Comparative Example 4: Production Example of Acrylate Compound Represented by Formula (7) In a 500 ml glass reaction vessel equipped with a stirrer, a cooler and a thermometer, 60.00 g (0.16 mol) of 9,9-bis(4-hydroxy-3-methylphenyl)fluorene, 0.22 g (0.0017 mol) of p-methoxyphenol, 35.29 g (0.35 mol) of triethylamine and toluene were added, and stirred at 25° C. Thereafter, 30.13 g (0.33 mol) of acrylic acid chloride was added, and the mixture was reacted for 2 hours while the above temperature was maintained. After the reaction, the reaction liquid was subjected to HPLC analysis, and the result showed that an acrylate compound represented by the formula (7) was produced in an amount of 89.6%. The obtained reaction liquid was neutralized by adding 5% sodium bicarbonate aqueous solution thereto, then washed with water twice, and concentrated under reduced pressure to obtain 61.7 g of an acrylate compound represented by the formula (7) (yield: 80.0% and HPLC purity: 93.0%). Table 3 shows the measurement results of the refractive index, Abbe number, melting point or glass transition temperature (Tg), and solubility in the diluent for the obtained acrylate compound represented by the formula (7).
  • 14
  • [ 88938-12-9 ]
  • [ 15852-73-0 ]
  • 9,9-bis[4-(3-(hydroxymethyl)phenyloxy)-3-methylphenyl]fluorene [ No CAS ]
YieldReaction ConditionsOperation in experiment
31.1% With 1,3-dimethyl-2-imidazolidinone; 8-quinolinol; potassium carbonate; copper(l) chloride at 140℃; for 72h; Inert atmosphere; 1 Example 1 In a 4-necked 2 L flask, under nitrogen stream, BCF167 g (0.44 mol),198 g (1.06 mol) of m-bromobenzyl alcohol,N,N′-dimethyl-2-imidazolidinone (DMI) 334 g, potassium carbonate 91.5 g (0.66 mol), copper(I) chloride 3.5 g (35.4 mmol)And 8-quinolinol 5.1 g(35.1 mmol) was charged,The reaction was carried out at 140°C for 72 hours.After cooling the reaction solution to room temperature,600 g of toluene,The liquid was extracted and separated with 300 g of ion-exchanged water. The organic layer was washed twice with 150 g of 1N hydrochloric acid to decompose insoluble matter (decomposed at pH 2-3), and washed twice with 100 g of ion-exchanged water.After that, neutralization treatment is performed twice with 150 g of a 2% by mass aqueous sodium hydroxide solution,The pH of the aqueous layer was adjusted to 7 by washing with 200 g of ion-exchanged water 10 times.By concentrating the organic layer under reduced pressure,329 g of a brown viscous liquid was obtained. The brown viscous liquid was dissolved at 50° C. with 450 g of toluene, seed crystals were added (added) and recrystallized overnight in a freezer, and the precipitate was washed with 50 g of toluene three times and collected.The same recrystallization operation is performed 5 times to collect the precipitate, and the precipitate is dried under reduced pressure at 60 to 80° C. to obtain the target compound represented by the following formula (2-1):9,9-bis[4-(3-(hydroxymethyl)phenyloxy)-3-methylphenyl]fluorene81.0 g (31.1% yield, 96.4 area% HPLC purity) were obtained in the form of light brown crystals.The measurement results of 1H-NMR are shown below.
  • 15
  • [ 88938-12-9 ]
  • [ 15852-73-0 ]
  • 9,9-bis[4-(3-(acryloyloxymethyl)phenyloxy)-3-methylphenyl]fluorene [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 1,3-dimethyl-2-imidazolidinone; copper(l) chloride; potassium carbonate; 8-quinolinol / 72 h / 140 °C / Inert atmosphere 2: 2-methoxy-phenol; p-toluenesulfonic acid monohydrate / toluene / 4 h / 60 - 115 °C / Dean-Stark; Inert atmosphere
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