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Chemical Structure| 89-79-2 Chemical Structure| 89-79-2
Chemical Structure| 89-79-2

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(-)-Isopulegol is a compound directly obtained from citronella oil through solid-supported acid catalys is and solvent-free microwave-assisted cyclization, showing high activity in reactions with carbonyl compounds and is used in antiviral activity studies.

Synonyms: l-Isopulegol; AI3-02176; Isopulegol

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Product Details of (-)-Isopulegol

CAS No. :89-79-2
Formula : C10H18O
M.W : 154.25
SMILES Code : O[C@H]1[C@H](C(C)=C)CC[C@@H](C)C1
Synonyms :
l-Isopulegol; AI3-02176; Isopulegol
MDL No. :MFCD00134655
InChI Key :ZYTMANIQRDEHIO-KXUCPTDWSA-N
Pubchem ID :170833

Safety of (-)-Isopulegol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P301+P312+P330-P302+P352-P305+P351+P338

Application In Synthesis of (-)-Isopulegol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 89-79-2 ]

[ 89-79-2 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 64-18-6 ]
  • [ 2385-77-5 ]
  • [ 42822-86-6 ]
  • [ 89-79-2 ]
  • 4
  • [ 2385-77-5 ]
  • [ 7664-93-9 ]
  • [ 42822-86-6 ]
  • [ 89-79-2 ]
  • 6
  • [ 106-23-0 ]
  • 2-[2,6-dimethyl-5-heptenyl]-4,4,8-trimethylhexahydro-1,3-benzodioxine [ No CAS ]
  • [ 42822-86-6 ]
  • [ 89-79-2 ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid;cetyltrimethylammonim bromide; In water; at 35℃; for 5.0h; A method for carrying out this invention is as indicated below. The actual detail of the processing will be known to those skilled in the art:1. A solution of hexadecyltrimethylammonium bromide (0.05%) in 5% sulphuric was charged into a reactor and vigorously stirred. Citronellal in an amount equivalent to 33.32.% of the total charge was fed into the reactor over a five hour period with the temperature being maintained at or below 350C. Stirring was continued for a further three hours.2. The stirring was stopped and the two phases were allowed to separate. The lower aqueous acid solution was run off to be used in further batches. The temperature should be maintained above 30C for ease of separation. <n="15"/>3. The organic layer was washed with a solution of mild alkali such as sodium carbonate or sodium bicarbonate to remove residual acid until an aliquot shaken with water showed a pH of 5.0 - 8.0. The product was filtered through a lOOmuM filter to remove residual water and any suspended solids.4. The resultant product is a clear or slightly opaque almost colourless, moderately viscous liquid with a slight pleasant floral odour quite unlike that of the starting material.Analysis of the product of the above process shows a typical composition: PMD-citronellal acetal 5-12%Isopulegole 7-14%/?alphara-menthane-3,8-diol remainder
  • 7
  • [ 106-23-0 ]
  • p-menthane-3,8-diol citronellal acetal [ No CAS ]
  • [ 42822-86-6 ]
  • [ 89-79-2 ]
  • 8
  • [ 106-23-0 ]
  • 2-[2,6-dimethyl-5-heptenyl]-4,4,8-trimethylhexahydro-1,3-benzodioxine [ No CAS ]
  • [ 42822-86-6 ]
  • [ 89-79-2 ]
  • [ 89-79-2 ]
  • [ 89-79-2 ]
  • [ 89-79-2 ]
 

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