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Chemical Structure| 89929-27-1 Chemical Structure| 89929-27-1

Structure of 89929-27-1

Chemical Structure| 89929-27-1

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Product Details of [ 89929-27-1 ]

CAS No. :89929-27-1
Formula : C17H23NO3
M.W : 289.37
SMILES Code : O=C(C(CC(C)C)C1)CC2N1CCC3=C2C=C(O)C(O)=C3
MDL No. :MFCD29918466
InChI Key :HKXSWCIZVQFEQQ-UHFFFAOYSA-N
Pubchem ID :59272827

Safety of [ 89929-27-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 89929-27-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 89929-27-1 ]

[ 89929-27-1 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 67-56-1 ]
  • [ 89929-27-1 ]
  • [ 718635-93-9 ]
YieldReaction ConditionsOperation in experiment
262.3 g With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 25 - 30℃; To a rnixture of tetrahydrofuran (2000 rnl), dihydroxy benzoquinoline cornpound (III) (250 g), rnethanol (276.8 g) and triphenylphosphine (679.9 g) was added a solution of diisopropylazodicraboxylate (DIAD) (524.1 g) in tetrahydrofuran (500 rnl) at 25-3OC. The reaction rnass was stirred for 3-6 hours at 25-30. The reaction rnass was concentrated under vacuurn. A rnixture of water (2500 rnl) and toluene (7500 rnl) was added to the concentrated rnass and the rnixture was stirred. The aqueous layer was separated and the organic layer was washed with 5percent aqueous sodi urn hydrogen sulphate solution (2500 rnl, 3 ti rnes). The aqueous layers were collected together and the pH was adjusted to 9-11 using aqueous arnrnonia solution (750 rnl). Dichlorornethane (2500 rnl) was added to it and the organic layer was separated and concentrated under vacuurn. Water (1250 rnl) was added to the concentrated rnass and the rnass was stirred for at 25- 3OC for 2 hours. The solid was filtered, washed with water and dried under vacuurn. Y i el d: 262.3g.
References: [1] Patent: WO2017/182916, 2017, A1, . Location in patent: Page/Page column 9.
 

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Technical Information

• Appel Reaction • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Chugaev Reaction • Clemmensen Reduction • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Corey-Kim Oxidation • Dess-Martin Oxidation • Fischer Indole Synthesis • Grignard Reaction • Henry Nitroaldol Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Jones Oxidation • Lawesson's Reagent • Leuckart-Wallach Reaction • Martin's Sulfurane Dehydrating Reagent • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Mitsunobu Reaction • Moffatt Oxidation • Oxidation of Alcohols by DMSO • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Alcohols • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Alcohols • Reactions of Aldehydes and Ketones • Reactions of Amines • Reactions with Organometallic Reagents • Reformatsky Reaction • Ritter Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Sharpless Olefin Synthesis • Specialized Acylation Reagents-Ketenes • Stobbe Condensation • Swern Oxidation • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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