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Chemical Structure| 142978-18-5 Chemical Structure| 142978-18-5
Chemical Structure| 142978-18-5

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Synonyms: CCVJ

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Product Details of 9-(2-Carboxy-2-cyanovinyl)julolidine

CAS No. :142978-18-5
Formula : C16H16N2O2
M.W : 268.31
SMILES Code : N#C/C(C(O)=O)=C\C1=CC2=C3C(CCCN3CCC2)=C1
Synonyms :
CCVJ
MDL No. :MFCD00274408
InChI Key :JXENNHTVELFRHV-NTEUORMPSA-N
Pubchem ID :5353485

Safety of 9-(2-Carboxy-2-cyanovinyl)julolidine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of 9-(2-Carboxy-2-cyanovinyl)julolidine

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 142978-18-5 ]

[ 142978-18-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 33985-71-6 ]
  • [ 372-09-8 ]
  • [ 142978-18-5 ]
YieldReaction ConditionsOperation in experiment
27% With triethylamine; In tetrahydrofuran; at 55℃;Inert atmosphere; Example 6a Synthesis of Julodine-Based Fluorescent Molecular Rotor (CCVJ) (0333) (0334) Julolidine-carboxaldehyde (0.5 g, 2.48 mmol, 1.0 eq.) and cyanoacetic acid (0.3170 g, 3.73 mmol, 1.5 eq.) was weighed into a 25 mL round-bottom flask flushed with argon. Triethylamine (0.69 mL, 4.97 mmol, 2.0 eq.) was then added to the reaction mixture after solvating in anhydrous THF. The reaction mixture was then heated to 55 C. overnight, then evaporated to dryness and purified via column chromatography to reddish-brown solids (0.18 g, 27%). (0335) 1H NMR (DMSO, 400 MHz) delta1.87 (m, 3H), 2.67 (t, J=6.3 Hz, 1H), 3.31 (t, J=5.9 Hz, 1H), 7.48 (s, 2H), 7.84 (s, 2H). 13C NMR (100 MHz, DMSO) delta 165.1, 152.8, 147.1, 130.7, 120.4, 119.5, 118.5, 117.5, 104.5, 49.4, 27.0, 20.6.
 

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