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Chemical Structure| 90055-47-3 Chemical Structure| 90055-47-3

Structure of 90055-47-3

Chemical Structure| 90055-47-3

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Product Details of [ 90055-47-3 ]

CAS No. :90055-47-3
Formula : C9H8Cl2O2
M.W : 219.06
SMILES Code : C1=C(C(Cl)C(OC)=O)C(=CC=C1)Cl
MDL No. :MFCD08061395
Boiling Point : No data available
InChI Key :BUGNHCGQRDZRSQ-UHFFFAOYSA-N
Pubchem ID :10998506

Safety of [ 90055-47-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 90055-47-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 90055-47-3 ]

[ 90055-47-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10421-85-9 ]
  • [ 90055-47-3 ]
YieldReaction ConditionsOperation in experiment
45% With phosphorus pentachloride; In methanol; a Methyl 1-chloro-(2-chlorophenyl)acetate 93.3 g (0.5 mol) of pure <strong>[10421-85-9]2-chloromandelic acid</strong> are mixed with 208 g (1 mol) of phosphorus pentachloride and are heated progressively. The reaction begins at 60 C. and the temperature rises to 100 C. Heating is continued for 2 h between 120 and 130 C. When the evolution of hydrogen chloride gas has ceased, the mixture is returned to room temperature, is distilled on the water pump and is then taken up with 200 ml of methanol. The mixture is refluxed for 2 h. The reaction mixture is concentrated by means of a rotary evaporator and is taken up with methylene chloride and water. After phase separation and drying over anhydrous magnesium sulphate, the methylene chloride is stripped off by means of a rotary evaporator, and this yields 121 g of crude ester which is distilled between 80 and 90 C. at a pressure of 0.15 mm Hg (19.95 Pa). In this way 54.8 g of methyl 1-chloro(2-chlorophenyl)acetate are obtained, assayed at 90% by HPLC (high pressure liquid chromatography). Yield: 45%.
 

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