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Chemical Structure| 900799-69-1 Chemical Structure| 900799-69-1

Structure of 900799-69-1

Chemical Structure| 900799-69-1

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Product Details of [ 900799-69-1 ]

CAS No. :900799-69-1
Formula : C15H13NO5
M.W : 287.27
SMILES Code : O=C(O)C1=CC(O)=CC(NC(OCC2=CC=CC=C2)=O)=C1
MDL No. :MFCD09817564

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Application In Synthesis of [ 900799-69-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 900799-69-1 ]

[ 900799-69-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 76045-71-1 ]
  • [ 501-53-1 ]
  • [ 900799-69-1 ]
YieldReaction ConditionsOperation in experiment
85% <strong>[76045-71-1]3-Amino-5-hydroxy-benzoic acid</strong> (50 g, 323 mmol, 1 eq) is suspended in a mixture of THF (150 ml) and aqueous Na2CO3 (300 ml). Benzyl chloroformate (55.7 ml, 323 mmol, 1 eq) is added to the reaction mixture, and the reaction is stirred for 20 h at room temperature. The mixture is diluted with Et2O and 4N HCl solution. The organic layer is separated, dried over sodium sulfate, filtered and concentrated to give the product (80 g, 85%).HPLC (Nucleosil C18HD, 4×70 mm, 3 mum, 20-100% AcCN (6 min), 100% AcCN (1.5 min)) retention time=3.63 min1H-NMR (400 MHz, d6-DMSO): 9.80 (s, 1H), 7.60 (s, 1H), 7.47-7.32 (m, 5H), 7.24 (s, 1H), 7.00 (s, 1H), 5.20 (s, 2H).
 

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