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Chemical Structure| 905564-60-5 Chemical Structure| 905564-60-5

Structure of 905564-60-5

Chemical Structure| 905564-60-5

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Product Details of [ 905564-60-5 ]

CAS No. :905564-60-5
Formula : C16H18BNO2
M.W : 267.13
SMILES Code : CCCCN1C2=C(C3=C1C=CC=C3)C=C(B(O)O)C=C2
MDL No. :MFCD30292895

Safety of [ 905564-60-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 905564-60-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 905564-60-5 ]

[ 905564-60-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 905564-60-5 ]
  • [ 4805-22-5 ]
  • [ 1443044-24-3 ]
YieldReaction ConditionsOperation in experiment
61% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; water; at 60℃; for 24h;Schlenk technique; Inert atmosphere; Compound 3(2.00g, 6.17mmol), 5,5′-dibromo-2,2′-bithiophene (4.85g, 14.97mmol), and (PPh3)4Pd(0) (0.87g, 0.75mmol) were added to a 100mL Schlenk flask and subjected to three vacuum/nitrogen refill cycles. THF (60mL) and a nitrogen degassed aqueous solution of 2M K2CO3(25mL) were added and stirred for 10min under nitrogen. The mixture was heated at 60C for 24h and monitored via thin layer chromatography for reaction completion. THF was removed using a rotovap and the product was extracted with dichloromethane, successively washed with water, and dried over MgSO4. Removal of the solvent afforded the crude product. The crude product was subjected to a silica gel column using a hexane/dichloromethane mixture (8:1 by volume) as eluent. A yellow solid ofcompound 5was isolated in 61% yield (2.13g).1H NMR (CDCl3)δ(ppm): 0.86-0.89 (t, 3H, -CH3), 1.27-1.32 (q, 2H, -CH2-), 1.74-1.77 (t, 2H, -CH2-), 4.39-4.41 (t, 2H, -N-CH2-), 7.17-8.47 (11H, Ph-H and Th-H).
 

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