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Chemical Structure| 916210-02-1 Chemical Structure| 916210-02-1

Structure of 916210-02-1

Chemical Structure| 916210-02-1

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Product Details of [ 916210-02-1 ]

CAS No. :916210-02-1
Formula : C7H3F3N2
M.W : 172.11
SMILES Code : N#CC1=CC=NC(C(F)(F)F)=C1
MDL No. :MFCD11848100
InChI Key :MLFFNKLBERSEPF-UHFFFAOYSA-N
Pubchem ID :53403825

Safety of [ 916210-02-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 916210-02-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 916210-02-1 ]

[ 916210-02-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 10386-27-3 ]
  • [ 129946-88-9 ]
  • [ 916210-02-1 ]
YieldReaction ConditionsOperation in experiment
93% With copper; In N,N-dimethyl-formamide; at 0 - 80℃; for 4h;Inert atmosphere; Under the protection of N2,To a 100 ml three-necked flask was added <strong>[10386-27-3]2-bromo-4-cyanopyridine</strong> (1.83 g, 0.01 mol).25 ml of DMF, Cu powder (1.92 g, 0.03 mol), stirred, and cooled to 0-5 ° C in an ice water bath. add Umemoto reagent (8.76g, 0.02mol).After stirring for 1 hour in an ice water bath,The temperature was further raised to 80 ° C and the reaction was carried out for 3 h. The reaction solution was taken for 19F NMR analysis.With OTf as internal standard, the yield is 93percent
 

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