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Chemical Structure| 916210-08-7 Chemical Structure| 916210-08-7

Structure of 916210-08-7

Chemical Structure| 916210-08-7

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Product Details of [ 916210-08-7 ]

CAS No. :916210-08-7
Formula : C10H8N2O2
M.W : 188.18
SMILES Code : N#CC1=CC=C(C(N2C)=C1)OCC2=O
MDL No. :MFCD21984796

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Application In Synthesis of [ 916210-08-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 916210-08-7 ]

[ 916210-08-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 134997-74-3 ]
  • [ 74-88-4 ]
  • [ 916210-08-7 ]
YieldReaction ConditionsOperation in experiment
52% With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20℃; for 2h; The title compound from the Preparative Example 20, Step A (549 mg) was dissolved in dry DMF (7 mL) and cooled to 0C. An excess of NaH and methyl iodide were added subsequently and the mixture was stirred for 2 h while warming to room temperature. The mixture was diluted with EtOAc, washed subsequently with IN aqueous HCl and saturated aqueous NaCl, dried (MgSO4), filtered, absorbed on silica and purified by chromatography (silica, cyclohexane/EtOAc) to afford the title compound as colorless needles (311 mg, 52%). [MH]+ = 189.
 

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