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Chemical Structure| 91873-05-1 Chemical Structure| 91873-05-1

Structure of 91873-05-1

Chemical Structure| 91873-05-1

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Product Details of [ 91873-05-1 ]

CAS No. :91873-05-1
Formula : C7H7IN2O2
M.W : 278.05
SMILES Code : O=[N+](C1=C(I)C=C(C)N=C1C)[O-]
MDL No. :MFCD27939546

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Application In Synthesis of [ 91873-05-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 91873-05-1 ]

[ 91873-05-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 15513-48-1 ]
  • [ 91873-05-1 ]
YieldReaction ConditionsOperation in experiment
90% With hydrogen iodide; In water; acetonitrile; at 70℃; for 20.0h; 4-Chloro-2,6-dimethyl-3-nitro-pyridine (1.1054 g, 5.9239 mmol), acetonitrile (4.0 mL), and aqueous hydroiodic acid (concentrated, 57percent, 4.0 mL) were combined and heated to 70 °C for 20 h. The mixture was partitioned between CH2CI2, aqueous sat'd Na2C03, and aqueous NaOH (1 M). The aqueous layer was extracted with CH2CI2. The combined organic phases were dried over Na2S04, filtered and concentrated. The residue was chromatographed on silica gel, eluting with 0- 100percent EtOAc in hexanes to yield 4-iodo-2,6-dimethyl-3-nitro-pyridine (1.48 g, 90percent). MS m/z 279. 1 [M+H]+
 

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