Alternatived Products of [ 924645-91-0 ]
Product Details of [ 924645-91-0 ]
CAS No. : | 924645-91-0 |
MDL No. : | MFCD14666483 |
Formula : |
C12H8FNO2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
217.20
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 924645-91-0 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
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Application In Synthesis of [ 924645-91-0 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 924645-91-0 ]
- 1
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[ 886444-12-8 ]
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[ 924645-91-0 ]
Yield | Reaction Conditions | Operation in experiment |
|
With potassium permanganate; In water; for 20h;Heating / reflux; |
(C) To a suspension of intermediate XXXIIb (0.44 g, 2.35 mmol) in water (25 ml) was added KMnO4 (0.82 g, 5.18 mmol) in two portions, the mixture heated at reflux for 20 h, cooled to RT. The resulting solid was filtered through celite, washed with water and EtOAc, and the two phases separated. The pH of aqueous solution was adjusted to 3, and the white precipitate that formed was isolated and dried to yield 2-(2-fluorophenyl)-pyridine-4-carboxylic acid (intermediate XXXIIc, 0.17 g, 33%). MW+1:218, MW-1:216. |