Alternatived Products of [ 925921-14-8 ]
Product Details of [ 925921-14-8 ]
CAS No. : | 925921-14-8 |
MDL No. : | MFCD19207586 |
Formula : |
C7H15NO
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
129.20
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 925921-14-8 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 925921-14-8 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 925921-14-8 ]
- 1
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[ 16636-51-4 ]
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[ 925921-14-8 ]
Yield | Reaction Conditions | Operation in experiment |
|
With borane-THF; In tetrahydrofuran; at 20℃; for 74.0h;Heating / reflux; |
Synthesis of 4; To a solution of 3 (2.0 g, 14 mmol) in THF (31 mL) was added dropwise via addition funnel 1.0 M BH3-THF (42 mL, 42 mmol). The solution was stirred at room temperature for 72 h and refluxed for 2 h. The solution was cooled, diluted with methanol (70 mL) and concentrated under reduced pressure. The residue was dissolved in methanol (70 mL) and 2 N HCI (70 mL) and refluxed for 1 h. The solution was cooled and the pH adjusted to 14 with a 6 N aqueous sodium hydroxide solution. The solution was cooled and the pH was made basic with 6 N NaOH. The mixture was extracted with methylene chloride (3 x 500 mL) and the combined organic layers were dried over sodium sulfate, filtered through diatomaceous earth, EPO <DP n="100"/>and concentrated under reduced pressure to afford 4 (1.7 g) which was used without further purification or characterization. |
- 2
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[ 53084-60-9 ]
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[ 7757-82-6 ]
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[ 925921-14-8 ]
Yield | Reaction Conditions | Operation in experiment |
200 mg |
With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 30℃; for 15h; |
LAH (107 mg, 2.8 mmol) was added portionwise to a solution of ethyl 3-aminocyclohexanecarboxylate (320 mg, 1.87 mmol) in THF (5 mL) at 0 C. and continued stirring at 25-30 C. for 15 h. The reaction mixture was quenched with aqueous saturated <strong>[7757-82-6]sodium sulphate</strong> solution, filtered the solid precipitate, washed the solid with THF; the filtrate collected was concentrated under reduced pressure to afford 200 mg of the title compound. MS (ESI): m/z 130 (M+H). |