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Chemical Structure| 92652-76-1 Chemical Structure| 92652-76-1

Structure of 92652-76-1

Chemical Structure| 92652-76-1

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Product Details of [ 92652-76-1 ]

CAS No. :92652-76-1
Formula : C15H19NO3
M.W : 261.32
SMILES Code : O=C(N1C2CC(O)CC1CC2)OCC3=CC=CC=C3
MDL No. :MFCD18883099
InChI Key :AXRYOOOSGBBQPJ-UHFFFAOYSA-N
Pubchem ID :46780768

Safety of [ 92652-76-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P233-P260-P261-P264-P270-P271-P280-P301+P312-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501

Application In Synthesis of [ 92652-76-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 92652-76-1 ]

[ 92652-76-1 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 92652-76-1 ]
  • C25H24F3N3O3 [ No CAS ]
  • 3
  • [ 92652-76-1 ]
  • C15H18INO2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 1H-imidazole; iodine; triphenylphosphine; In dichloromethane; for 0.5h; Into a 250mL round-bottomed flask were sequentially added 150mL of dichloromethane, 40mmol of compound 24, followed by 60mmol of imidazole, 52mmol of triphenylphosphine, stirred and cooled to 0, and then added 48mmol of iodine at a time, and continued to react at 0 for 30min. After that, it was transferred to room temperature and reacted overnight. After the reaction was completed, the insoluble matter was removed by suction filtration, the filter cake was washed with dichloromethane (20mL×3), the filtrate was combined, the solvent was removed under reduced pressure, 30mL of deionized water was added to the reaction residue, and Adjust the pH to 8-9 with saturated aqueous sodium carbonate solution, and extract with dichloromethane (50 mL×3). The extract is depressurized to remove the solvent, and the crude product is separated by column chromatography to obtain the target product.
 

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