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Chemical Structure| 93298-14-7 Chemical Structure| 93298-14-7

Structure of 93298-14-7

Chemical Structure| 93298-14-7

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Product Details of [ 93298-14-7 ]

CAS No. :93298-14-7
Formula : C14H12INO2
M.W : 353.16
SMILES Code : IC1=CC=C(C=C1)NC(OCC2=CC=CC=C2)=O
MDL No. :MFCD00745576
InChI Key :IXSZDTNGTXGHJS-UHFFFAOYSA-N
Pubchem ID :1245679

Safety of [ 93298-14-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H332
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P363-P501

Application In Synthesis of [ 93298-14-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93298-14-7 ]

[ 93298-14-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 93298-14-7 ]
  • [ 25015-63-8 ]
  • [ 363186-06-5 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In 1,4-dioxane; water; ethyl acetate; REFERENCE EXAMPLE 133 [4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamic acid phenylmethyl ester To a solution of (4-iodophenyl)carbamic acid phenylmethyl ester (6.50 g, 18.4 mmol) and triethylamine (7.7 mL, 55 mmol) in 1,4-dioxane (35 mL), [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II) dichloromethane complex (150 mg, 0.184 mmol) was added, and 4,4,5,5-tetramethyl-1,3,2-dioxaborolane (5.9 mL, 41 mmol) was added dropwise. The resultant mixture was stirred at 85 C for 2.5 hours under nitrogen atmosphere. The reaction mixture was cooled with ice, combined with water, and extracted twice with ethyl acetate. The combined organic layer was washed with water and brine, dried through sodium sulfate-silica gel (eluding with ethyl acetate), and concentrated under reduced pressure. The residue was subjected to a column chromatography on a silica gel (hexane/ethyl acetate, 10:1 followed by 4:1) to obtain the title compound (5.47 g, yield: 84%). An oil. 1H NMR (CDCl3) δ 1.33 (12H, s), 5.20 (2H, s), 6.76 (1H, br s), 7.25-7.52 (7H, m), 7.75 (2H, d, J = 8.4 Hz).
 

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