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Chemical Structure| 93397-90-1 Chemical Structure| 93397-90-1

Structure of 93397-90-1

Chemical Structure| 93397-90-1

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Product Details of [ 93397-90-1 ]

CAS No. :93397-90-1
Formula : C20H18N2O3
M.W : 334.37
SMILES Code : O=C1C2=CC(O)=CC=C2C3=NC4=C(C=C(N(CC)CC)C=C4)OC3=C1
MDL No. :MFCD32220293

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Application In Synthesis of [ 93397-90-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93397-90-1 ]

[ 93397-90-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 93397-90-1 ]
  • [ 83883-26-5 ]
  • C36H36N2O7 [ No CAS ]
YieldReaction ConditionsOperation in experiment
70.3% (0333) A 300 ml four-neck flask was charged with mesyl chloride (0.25 g, 0.0022 mol) and THF (4.38 g). In a nitrogen atmosphere at -30 C., a solution of TEA (0.22 g, 0.0022 mol) and 4-(6-acryloxy-hex-1-yloxy)benzoic acid (0.53 g, 0.0018 mol) in THF (4.38 g) was added dropwise to the mixture and stirred at 0 C. for 2 hours. After a solution of TEA (0.22 g, 0.0022 mol) and DMAP (0.002 g) in THF (4.38 g) was further added to the mixture, intermediate 6 (0.60 g, 0.0018 mol) obtained in step 1 was added to the mixture. The mixture was stirred at room temperature overnight. The organic layer was extracted. After the solvent was removed by distillation, the residue was separated by silica gel column chromatography (eluent: chloroform:ethyl acetate=20:1). The separated product was crystallized from methanol and dried under reduced pressure at 40 C. to give 0.77 g of the desired product, compound B-221 (70.3% yield).
 

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