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Structure of 93524-95-9

Chemical Structure| 93524-95-9

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Product Details of [ 93524-95-9 ]

CAS No. :93524-95-9
Formula : C8H7NO
M.W : 133.15
SMILES Code : OCC#CC1=CC=NC=C1
MDL No. :MFCD00168868
InChI Key :QYFHTILWEGBMKR-UHFFFAOYSA-N
Pubchem ID :12181443

Safety of [ 93524-95-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 93524-95-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 93524-95-9 ]

[ 93524-95-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 93524-95-9 ]
  • [ 7037-49-2 ]
YieldReaction ConditionsOperation in experiment
43% With palladium 10% on activated carbon; hydrogen; In acetic acid; at 20℃; under 760.051 Torr; for 6h;Inert atmosphere; General procedure: A solution of 3-(2?-pyridinyl)-2-propyn-1-ol (1a), or 3-(3?-pyridinyl)-2-propyn-1-ol (1b), or 3-(4?-pyridinyl)-2-propyn-1-ol (1c, 30 mg, 0.23 mmol, 1.0 eq) in AcOH (5.6 mL) was treated with 10percent Pd/C (1.2 g, 1.13 mmol, 5.0 eq) and hydrogenated at balloon pressure at room temperature. After stirring for 6 h at room temperature, the insoluble was separated by filtration through Celite eluting with MeOH and then washed with Et2O. The filtrate afforded 3-piperidin-2?-yl-propan-1-ol (2a) as a colorless solid (18.5 mg, 0.13 mmol, 57percent);
 

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[ 93524-95-9 ]

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