Home Cart Sign in  
Chemical Structure| 94163-98-1 Chemical Structure| 94163-98-1

Structure of 94163-98-1

Chemical Structure| 94163-98-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 94163-98-1 ]

CAS No. :94163-98-1
Formula : C18H20ClN
M.W : 285.81
SMILES Code : [H]Cl.C1(C2=CC=CC=C2)=CCN(CC3=CC=CC=C3)CC1

Safety of [ 94163-98-1 ]

Application In Synthesis of [ 94163-98-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 94163-98-1 ]

[ 94163-98-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 94163-98-1 ]
  • [ 10272-49-8 ]
YieldReaction ConditionsOperation in experiment
97% With palladium 10% on activated carbon; hydrogen; In ethanol; for 44h; General procedure: The starting material (either 1-benzyl-4-aryl-1,2,3,6-tetrahydropyridine, its hydrochloride salt; or 4-aryl-1,2,3,6-tetrahydropyridinium chloride) (1 mmol) was dissolved in the specified alcohol (10 mL) and stirred vigorously under an atmosphere of hydrogen in the presence of 10% palladium on carbon (0.1 molar equivalents). The progress of the reaction was monitored by TLC (10% methanol / chloroform with 1% ammonia) every 12 h and, if incomplete, additional palladium on carbon (0.01 molar equivalents) was added. When the starting material had been completely consumed (TLC, Rf usually 0.75-0.95 for the 1-benzyl compounds, Rf usually 0.15-0.25 for the tetrahydropyridines) and the presence of the desired product was evident (TLC, Rf usually 0.1-0.2) the reaction was worked up by filtration through Celite followed by rinsing with the alcohol used (2 × 5 mL) and removing all solvent in vacuo to give the title compound as a solid. If the final product was deemed pure enough for initial biological evaluation (>95% by HPLC), it was dried under vacuum in the presence of phosphorous pentoxide. If the final product was not sufficiently pure enough for initial testing (<95% by HPLC), it was either recrystallized or subject to preparative HPLC as described in the specific procedure below.
 

Historical Records