Home Cart Sign in  
Chemical Structure| 944896-82-6 Chemical Structure| 944896-82-6

Structure of 944896-82-6

Chemical Structure| 944896-82-6

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 944896-82-6 ]

CAS No. :944896-82-6
Formula : C6H4ClN3
M.W : 153.57
SMILES Code : ClC1=CC=NC2=NC=CN12
MDL No. :MFCD10698094
Boiling Point : No data available

Safety of [ 944896-82-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 944896-82-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 944896-82-6 ]

[ 944896-82-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1450-93-7 ]
  • [ 262293-82-3 ]
  • [ 944896-82-6 ]
YieldReaction ConditionsOperation in experiment
A. IMIDAZO[ I^-A]PYRIMIDINE-S-CARBOXYLIC ACID (ADAMANTAN-1-YLMETHYL)-AMIDE; Step 1. S-Chloro-imidazori^-alpyrimidine; In a round bottom flask, <strong>[1450-93-7]2-aminoimidazole sulfate</strong> (0.264g, 1.0 mmol) is added to ethyl 3,3- dimethoxypropionate (0.296 g, 2.0 mmol). Piperidine (5 muL) and EtOH (5 mL) are then added and the flask is heated to reflux overnight. At RT, /p-toluenesulfonic acid monohydrate (15 mg) is added and the reaction is returned to reflux for 6 h. At RT, freshly powdered K2CO3 (0.415g, 3.0 mmol) is added and the reaction is heated to reflux overnight. The reaction is then concentrated to dryness and the residue is triturated with CHCl3 (10 mL) and again concentrated to dryness. The residue is treated with POCl3 (2.0 mL, 21.5 mmol) and heated to 90 °C for 1.5 h, and then to 115 °C for 1 h. At RT, the <n="68"/>reaction is concentrated to dryness, and then dissolved in CH2Cl2 and washed with NaHCO3 (sat.) followed by brine. The organic solution is dried over Na2SO4, filtered and concentrated to dryness. The residue is purified via silica gel chromatography using EtOAc to afford the title compound. 1H NMR (400 MHz, CDCl3 with 5percent CD3OD (Wv)) delta 8.44 (dd, / = 6.8, 0.8, 1 H), 7.70 (d, J = 0.8, 1 H), 7.57 (bs, 1 H), 6.92 (dd, J = 6.8, 0.8, 1H).
 

Historical Records

Technical Information

Categories